Edico Genome

Edico Genome is a company based in San Diego, California that sells a product for processing DNA sequencing data.

## History

The company was founded in 2013 by Pieter van Rooyen, Robert McMillen, and Michael Ruehle, using office space at a company called EvoNexus in San Diego.[1]

Edico Genome announced $10 million in venture capital financing in July 2014, which was led by Qualcomm Ventures and included Axon Ventures and Gregory T. Lucier, the former chairman and CEO of Life Technologies.[2][3][4][5]

Following the advent of the $1000 genome,[6] enabled by Illumina’s HiSeq X Ten, the amount of data generated[7] by next-generation sequencing has increased[8] exponentially,[9] and is outpacing Moore’s Law. DRAGEN is a reconfigurable Bio-IT Processor that is integrated on a PCIe card with accompanying software sold as a platform as a service. The processor is loaded with algorithms for DNA sequencing. It supports sequencing instruments such as Illumina’s HiSeq X Ten, Thermo Fischer’s Ion Proton Sequencer and Pacific Biosciences’ PacBio RS II.

The processor reduces the time needed to analyze a whole human genome, from 24 hours to 18 minutes.[10] It also reduces associated costs as it replaces the high-end computer servers otherwise needed for genome analysis as well as the required IT infrastructure, without compromising accuracy.[11]

DRAGEN was announced in October 2014.[12] Edico Genome made its first sale[13] of DRAGEN[14] in September 2014 to Sequenom, a San Diego company focused on non-invasive prenatal testing.

In December 2014, DRAGEN got a marketing mention.[15][16]

In September, 2015, Edico Genome and the Children's Mercy Kansas City published a study showing the diagnosis of critically ill newborns in just 26 hours using DRAGEN.[17]

Edico Genome’s board of directors includes Lucier, Eric Topol, professor of genomics at The Scripps Research Institute; Charles Cantor, chief scientific officer of Sequenom; and Nils Homer, genomics informatics leader at the Broad Institute.

## References

1. ↑ "Edico Genome". http://evonexus.org/evonexus-companies/edico-genome/.
2. ↑ Philippidis, Alex (July 17, 2014). "Edico Genome Draws Greg Lucier among Investors". Genetic Engineering and Biotechnology News. http://www.genengnews.com/gen-news-highlights/edico-processor-s-clinical-potential-draws-greg-lucier-among-investors/81250114/. Retrieved 6 August 2014.
3. ↑ Primack, Dan (July 17, 2014). "Deals of the day: GE to sell home appliance unit?". Fortune. http://fortune.com/2014/07/17/deals-of-the-day-ge-home-appliance/. Retrieved 6 August 2014.
4. ↑ Bigelow, Bruce (July 17, 2014). "Edico Raises $10M to Accelerate Processing of Gene Sequencing Data". Xconomy. http://www.xconomy.com/san-diego/2014/07/17/edico-raises-10m-to-accelerate-processing-of-gene-sequencing-data/. Retrieved 6 August 2014.
5. ↑ Fikes, Brad (July 17, 2014). "Genome Chip Startup Gets $10 Million". The San Diego Union-Tribune. Archived from the original on March 6, 2016. https://web.archive.org/web/20160306020406/http://www.sandiegouniontribune.com/news/2014/jul/17/tp-genome-chip-startup-gets-10-million/.
6. ↑ Herper, Matt (January 14, 2014). "The $1,000 Genome Arrives -- For Real, This Time". Forbes. https://www.forbes.com/sites/matthewherper/2014/01/14/the-1000-genome-arrives-for-real-this-time/. Retrieved 6 August 2014.
7. ↑ Baxt, Josh (February 3, 2015). "Forget Smartphones—Genomic Data is the Next Big Deal, Says Edico Genome CEO". BioSpace. http://www.biospace.com/News/forget-smartphonesgenomic-data-is-the-next-big/363097. Retrieved 23 February 2015.
8. ↑ Parmar, Arundhati (August 14, 2014). "As Genomics Moves to Clinical Domain, Bio-IT Plays Key Role". Medical Device & Diagnostic Industry. http://www.mddionline.com/article/genomics-moves-clinical-domain-opportunities-abound-firms-81414. Retrieved 23 February 2015.
9. ↑ Bigelow, Bruce (April 17, 2014). "Edico Genome Aims at Data Processing Bottleneck in Whole Genome Sequencing". Xconomy. http://www.xconomy.com/san-diego/2014/04/17/edico-genome-aims-at-data-processing-bottleneck-in-genome-sequencing/. Retrieved 23 February 2015.
10. ↑ Pedersen, Amanda (July 18, 2014). "Edico Genome raises $10M Series A to commercialize bioinformatics chip". Medical Device Daily. http://www.medicaldevicedaily.com/servlet/com.accumedia.web.Dispatcher?next=bioWorldHeadlines_article&forceid=87009. Retrieved 6 August 2014.
11. ↑ Kling, Jim (July 17, 2014). "Edico Genome: Powering up genome analysis". Start-Up. http://www.pharmamedtechbi.com/publications/start-up/19/7/edico-genome-inc. Retrieved 6 August 2014.
12. ↑ Fikes, Bradley (October 22, 2014). "Edico starts selling high-powered genome processor". U-T San Diego. http://www.utsandiego.com/news/2014/oct/22/edico-launches-dragen-genome/. Retrieved 23 February 2015.
13. ↑ Oldach, Laurel (September 4, 2014). "Edico Genome Makes First Sale of NGS Processor". Bio-IT World. http://www.bio-itworld.com/2014/9/4/edico-genome-makes-first-sale-ngs-processor.html. Retrieved 23 February 2015.
14. ↑ "Sequenom Taps Edico's Infrastructure for NIPT Data Analysis". GenomeWeb. September 3, 2014. https://www.genomeweb.com/informatics/sequenom-taps-edicos-infrastructure-nipt-data-analysis. Retrieved 23 February 2015.
15. ↑ "San Diego biotechs dominate innovation list". http://www.sandiegouniontribune.com/news/2014/dec/01/san-diego-innovation-scientist-edico-illumina/.
16. ↑ "Top 10 Innovations 2014 | The Scientist Magazine®". http://www.the-scientist.com/?articles.view/articleNo/41486/title/Top-10-Innovations-2014/.
17. ↑ Miller, Neil A.; Farrow, Emily G.; Gibson, Margaret; Willig, Laurel K.; Twist, Greyson; Yoo, Byunggil; Marrs, Tyler; Corder, Shane et al. (2015-09-30). "A 26-hour system of highly sensitive whole genome sequencing for emergency management of genetic diseases". Genome Medicine 7 (1). doi:10.1186/s13073-015-0221-8. ISSN 1756-994X. PMID 26419432. PMC 4588251. http://genomemedicine.biomedcentral.com/articles/10.1186/s13073-015-0221-8. Retrieved March 21, 2017.

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