List of adverse effects of lurasidone

This is a list of adverse effects of the antipsychotic drug lurasidone, sorted by frequency of occurrence.[1][2][3]

## Contents

* 1 Very common
* 2 Common
* 3 Uncommon
* 4 Rare
* 5 Unknown frequency
* 6 References

## Very common[edit | edit source]

Very common (>10% incidence) adverse effects include:

* Somnolence (dose-dependent; produces an intermediate degree of sedation compared to other atypical antipsychotics[4])
* Akathisia (dose-dependent)
* Fasting glucose increased
* Nausea
* Parkinsonism

## Common[edit | edit source]

Common (1–10% incidence) adverse effects include:

* Vomiting
* Dyspepsia
* Agitation
* Anxiety
* Dystonia
* Dizziness
* Fatigue
* Back pain
* Restlessness
* Hypersalivation
* Weight gain[5]

## Uncommon[edit | edit source]

Uncommon (0.1–1% incidence) adverse effects include:

* Orthostatic hypotension
* Syncope
* Stroke
* Seizure
* Suicidal ideation
* Elevated serum creatinine

## Rare[edit | edit source]

Rare (0.01–0.1% incidence) adverse effects include:

* Agranulocytosis
* Leukopaenia
* Neutropaenia
* Tardive dyskinesia
* Neuroleptic malignant syndrome

## Unknown frequency[edit | edit source]

Unknown frequency adverse effects include:

* Transient ischaemic attack
* Hyperprolactinaemia (seems to be a rather prominent adverse effect according to a meta-analysis[4])
* Hypothermia

## References[edit | edit source]

1. ↑ Truven Health Analytics, Inc. DrugPoint System (Internet) [cited 2013 Oct 1]. Greenwood Village, CO: Thomsen Healthcare; 2013.
2. ↑ lurasidone (Rx) - Latuda [Internet]. Medscape Reference. [cited 2013 Oct 1]. Available from: http://reference.medscape.com/drug/latuda-lurasidone-999605#4 Archived 2021-08-17 at the Wayback Machine
3. ↑ LATUDA (lurasidone hydrochloride) tablet, film coated [Bushu Pharmaceutical, LTD.] [Internet]. DailyMed. 2010 [cited 2013 Oct 1]. Available from: http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=88a244d1-eddb-499c-bee2-e1f49056e78f Archived 2021-11-25 at the Wayback Machine
4. ↑ 4.0 4.1 Leucht, S; Cipriani, A; Spineli, L; Mavridis, D; Orey, D; Richter, F; Samara, M; Barbui, C; Engel, RR; Geddes, JR; Kissling, W; Stapf, MP; Lässig, B; Salanti, G; Davis, JM (September 2013). "Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis". Lancet. 382 (9896): 951–962. doi:10.1016/S0140-6736(13)60733-3. PMID 23810019.
5. ↑ Ketter, T. A; Sarma, K; Silva, R; Kroger, H; Cucchiaro, J; Loebel, A (2016-02-26). "LURASIDONE IN THE LONG‐TERM TREATMENT OF PATIENTS WITH BIPOLAR DISORDER: A 24‐WEEK OPEN‐LABEL EXTENSION STUDY". Depression and Anxiety. 33 (5): 424–434. doi:10.1002/da.22479. PMC 5069590. PMID 26918425.