Isopropyl myristate

Isopropyl myristate[1]

Names
Preferred IUPAC name

Propan-2-yl tetradecanoate

Other names

Tetradecanoic acid, 1-methylethyl ester
Myristic acid isopropyl ester

Identifiers

CAS Number

* 110-27-0 Y

3D model (JSmol)

* Interactive image

ChEMBL |

* ChEMBL207602

ChemSpider |

* 7751 Y

EC Number |

* 203-751-4

KEGG |

* D02296 Y

MeSH | C008205

PubChem CID

* 8042

RTECS number |

* XB8600000

UNII |

* 0RE8K4LNJS Y

InChI

* InChI=1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3 N

Key: AXISYYRBXTVTFY-UHFFFAOYSA-N N

* InChI=1/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3

Key: AXISYYRBXTVTFY-UHFFFAOYAN

SMILES

* CCCCCCCCCCCCCC(=O)OC(C)C

Properties

Chemical formula

| C17H34O2
Molar mass | 270.457 g·mol−1
Density | 0.85 g/cm3
Boiling point |  167 °C (333 °F; 440 K) at 9 mmHg
Hazards
NFPA 704 (fire diamond)  |

Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

N verify (what is YN ?)
Infobox references

Tracking categories (test):

* SizeSet

Isopropyl myristate (IPM) is the ester of isopropyl alcohol and myristic acid. It is a colorless and odorless liquid that is a common ingredient in pharmaceutical and cosmetic preparations.[2]

## Contents

* 1 Uses
* 2 Adverse effects
* 3 References
* 4 External links

## Uses

Isopropyl myristate is a polar emollient and is used in cosmetic and topical pharmaceutical preparations as a penetration enhancer where skin absorption is desired.[3]

It is also used as a treatment for head lice.[4] It is also in flea and tick killing products for pets.

It is used to remove bacteria from the oral cavity as the non-aqueous component of the two-phase mouthwash product "Dentyl pH".

Isopropyl myristate is also used as a solvent in perfume materials, and in the removal process of prosthetic make-up.

Hydrolysis of the ester from isopropyl myristate can liberate the acid and the alcohol. The acid is theorized to be responsible for decreasing of the pH value of formulations.[5][6]

## Adverse effects

Isopropyl myristate is frequently classified as a comedogenic compound and may worsen acne vulgaris and promote the development of open and closed comedones, especially when used in high concentrations. This effect is largely attributed to follicular hyperkeratosis, a process where the compound induces an abnormal accumulation of keratinocytes that forms a plug and causes an obstruction within a hair follicle.[3]

## References

1. ↑ "SAFETY DATA SHEET". 22 September 2009. https://www.fishersci.com/store/msds?partNumber=AC412851000&countryCode=US&language=en.
2. ↑ Allen, Loyd V. (19 August 2019). "Testosterone 2.5% in Isopropyl Myristate 5% Topical Gel". https://www.uspharmacist.com/article/testosterone-25-in-isopropyl-myristate-5-topical-gel.
3. ↑ 3.0 3.1 "Comedogenicity in cosmeceuticals: A review of clinical relevance, regulatory gaps, and future directions". JAAD Reviews 6: 78–83. December 2025. doi:10.1016/j.jdrv.2025.09.002. https://linkinghub.elsevier.com/retrieve/pii/S2950198925000881. Retrieved 20 January 2026.
4. ↑ "Anti-Lice Treatments". https://www.lice.ca/treatment/anti_lice_insecticide.html.
5. ↑ Wen, Z.; Fang, L. and He, Z. (2009). Effect of chemical enhancers on percutaneous absorption of daphnetin in isopropyl myristate vehicle across rat skin in vitro. Drug Deliv, 16: 214-223
6. ↑ Engelbrecht, T.; Demé, B.; Dobner, B. and Neubert, R. (2012). Study of the influence of the penetration enhancer isopropyl myristate on the nanostructure of stratum corneum lipid model membranes using neutron diffraction and deuterium labelling. Skin Pharmacol Physiol, 25:200-7

## External links

* Isopropyl myristate in the Consumer Product Information Database

* v
* t
* e

Cosmetics

Face|

* Anti-aging cream
* BB cream
* Botulinum toxin (Botox)
* CC cream
* Concealer
* Cotton pad
* Cleanser
* DD cream
* Facial
* Facial toning
* Foundation
* Moist toilette
* Moisturizer
* Permanent makeup
* Primer
* Powder
* Rouge
* Toner
* Veil
* Venetian ceruse

Lips|

* Lipstick
* Balm
* Gloss
* Liner
* Plumper
* Stain

Eyes|

* Blepharoplasty
* Circle contact lens
* Eyelash extensions
* Eyelid glue
* Eye liner
* Eye shadow
* Kohl
* Mascara

Hair|

* Conditioner
* Hair coloring and bleaching
* Removal
* chemical
* electric
* laser
* IPL
* plucking
* shaving
* threading
* waxing
* Shampoo
* Sindoor
* Styling products
* gel
* mousse
* pomade
* spray
* wax

Nails|

* Artificial nails
* Buffing
* Manicure
* Nail polish
* Pedicure

Body|

* Body powder
* Cold cream
* Lotion
* Peeling
* Plastic surgery
* Skin whitening
* Sunless tanning

Related topics|

* Cosmetic electrotherapy
* Cosmetic ingredients
* Cosmetics advertising
* Cosmetic packaging
* Cosmetology
* History of cosmetics
* Cosmetic industry
* Male cosmetics

Major cosmetic brands

* Ahava
* Almay
* AmorePacific
* Anastasia Beverly Hills
* Anna Sui
* Aqua Net
* Artistry
* Aveda
* Avon
* Bath & Body Works
* Benefit
* Biotherm
* Bobbi Brown
* Bonne Bell
* Brihans Natural Products
* Bumble and bumble
* Burt's Bees
* Carol's Daughter
* Clarins
* Clinique
* Coty
* ColourPop Cosmetics
* CoverGirl
* Creme 21
* Cutex
* Daigaku Honyaku Center
* Elizabeth Arden, Inc.
* Estée Lauder
* elf
* Etude House
* Fabergé
* Farmec
* Fenty Beauty
* Garnier
* Guerlain
* Hard Candy
* Helena Rubinstein
* Jeffree Star Cosmetics
* Kao Corporation
* Kevyn Aucoin
* Kiehl's
* Kylie Cosmetics
* Lancôme
* Laneige
* Laura Mercier
* Laura Mercier Cosmetics
* Lise Watier
* L'Oréal
* L'Occitane
* Love Cosmetics
* Lush
* MAC Cosmetics
* Make Up For Ever
* Mary Kay
* Max Factor
* Maybelline
* Missha
* Molton Brown
* NARS
* Natura
* Natural Wonder
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* Neal's Yard Remedies
* Neutrogena
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* NYX Cosmetics
* O Boticário
* OPI
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* Origins
* Paula Begoun
* Pond's
* Red Earth
* Revlon
* Richard Hudnut
* Rimmel
* Sephora
* Shiseido
* Shu Uemura
* SimplySiti
* Sinful Colors
* SK-II
* SkinCeuticals
* Skin Food
* Stila
* Tarte Cosmetics
* The Body Shop
* The Face Shop
* Ulta Beauty
* Ultima II
* Urban Decay
* Vaseline
* Vichy
* Victoria's Secret
* Wella
* Yves Rocher

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