Tricarboxylic acid

Short description: Organic carboxylic acid

A tricarboxylic acid is an organic carboxylic acid that contain three carboxyl functional groups (−COOH). A well-known example is citric acid.

## Contents

* 1 Prominent examples
* 2 Some prominent substituted tricarboxylic acids
* 3 See also
* 4 References
* 5 Literature

## Prominent examples

Common name | IUPAC name | Molecular formula | Structural formula

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citric acid | 2-hydroxypropane-1,2,3-tricarboxylic acid | C6H8O7 |
isocitric acid | 1-hydroxypropane-1,2,3-tricarboxylic acid | C6H8O7 |
aconitic acid | prop-1-ene-1,2,3-tricarboxylic acid | C6H6O6 | File:cis-aconitic acid structure.png

(cis-form and trans-form)

propane-1,2,3-tricarboxylic acid | propane-1,2,3-tricarboxylic acid | C3H5(COOH)3 |
agaric acid | 2-hydroxynonadecane-1,2,3-tricarboxylic acid | C22H40O7 | 250px
trimesic acid | benzene-1,3,5-tricarboxylic acid | C9H6O6[1] |

## Some prominent substituted tricarboxylic acids

Citric acid, is used in the citric acid cycle - also known as the tricarboxylic acid (TCA) cycle or Krebs cycle - which is fundamental to all aerobic organisms.

Nitrilotriacetic acid

Nitrilotriacetic acid (NTA) is a chelating agent for Ca2+, Co2+, Cu2+, and Fe3+.[2]

## See also

* Citric acid cycle (tricarboxylic acid cycle)
* Dicarboxylic acid
* Mellitic acid
* Nitrilotriacetic acid

## References

1. ↑ Röhrscheid, Freimund (2000). "Carboxylic Acids, Aromatic". Ullmann's Encyclopedia of Industrial Chemistry. doi:10.1002/14356007.a05_249. ISBN 978-3-527-30385-4.
2. ↑ Schmidt, Thomas; Gousetis, Charalampos; Opgenorth, Hans-Joachim (2022). "Ullmann's Encyclopedia of Industrial Chemistry". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a17_377.pub3.

## Literature

* Ryan J. Mailloux, Robin Bériault, Joseph Lemire, Ranji Singh, Daniel R. Chénier, Robert D. Hamel, Vasu D. Appanna (2007). "The Tricarboxylic Acid Cycle, an Ancient Metabolic Network with a Novel Twist.". PLOS ONE 2 (8): e690. doi:10.1371/journal.pone.0000690. PMID 17668068. Bibcode: 2007PLoSO...2..690M.

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