Phenylpiperazine

Names
Preferred IUPAC name

1-Phenylpiperazine

Identifiers

CAS Number

* 92-54-6 Y

3D model (JSmol)

* Interactive image

ChEMBL |

* ChEMBL9434 Y

ChemSpider |

* 6829 Y

PubChem CID

* 7096

UNII |

* J9225CBI7D Y

InChI

* InChI=1S/C10H14N2/c1-2-4-10(5-3-1)12-8-6-11-7-9-12/h1-5,11H,6-9H2 Y

Key: YZTJYBJCZXZGCT-UHFFFAOYSA-N Y

SMILES

* c1cc(ccc1)N2CCNCC2

Properties

Chemical formula

| C10H14N2
Molar mass | 162.23 g/mol
Appearance  | clear colourless to yellow liquid
Density | 1.028g/cm3
Melting point |  18.8 °C (65.8 °F; 291.9 K)
Boiling point |  287.2 °C (549.0 °F; 560.3 K) at 760mmHg

Solubility in water

| insoluble
Hazards
Flash point |  138.3 °C (280.9 °F; 411.4 K)

Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Y verify (what is YN ?)
Infobox references

1-Phenylpiperazine is a simple chemical compound featuring a phenyl group bound to a piperazine ring. The suffix ‘-piprazole’ is sometimes used in the names of drugs to indicate they belong to this class.[1]

1-Phenylpiperazine is toxic, its oral LD50 in rats is 210 mg/kg.[2]

## Contents

* 1 List phenylpiperazine derivatives
* 2 See also
* 3 References
* 4 External links

## List phenylpiperazine derivatives

1. Alpertine [27076-46-6]
2. BP 554 [82900-57-0]
3. Butropipazone [2354-61-2]
4. CAM89 alluded to here: WO patent 2018102233
5. Centphenaquin [98459-16-6]
6. Centpropazine [91315-34-3] [34675-77-9]
7. Clodoxopone [71923-34-7]
8. Dropropizine [17692-31-8]
9. Etoperidone
10. FAUC-299 [313972-96-2]
11. FAUC-312 [562104-72-7]
12. LASSBio-579 [591774-47-9]
13. LASSBio-581 [591774-48-0]
14. LASSBio-632
15. LASSBio-680
16. LASSBio-724
17. LASSBio-729 [66307-58-2]
18. LASSBio-730
19. McN 261 [1044-59-3]
20. Nefazodone
21. Niaprazine
22. Oxypertine
23. PD-158771 [189152-50-9]
24. PO-219
25. Trazodone
26. WIN 18,437 [4121-77-1]

## See also

* Substituted piperazine
* Serotonin antagonist and reuptake inhibitor
* Benzylpiperazine
* Diphenylpiperazine
* Diphenylmethylpiperazine
* Pyridinylpiperazine
* Pyrimidinylpiperazine

## References

1. ↑ World Health Organization (WHO) (2006). "The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances". https://www.who.int/medicines/services/inn/RevisedFinalStemBook2006.pdf.
2. ↑ "1-Phenylpiperazine". https://pubchem.ncbi.nlm.nih.gov/compound/7096#section=Toxicity&fullscreen=true.

## External links

* v
* t
* e

Piperazines

Simple piperazines
(no additional rings)|

* 1-Cyclohexylpiperazine
* Aminoethylpiperazine
* Diethylcarbamazine
* HEPPS
* Midafotel
* Piperazine
* PIPES

Phenylpiperazines|

* Acaprazine
* Antrafenine
* Aripiprazole
* Batoprazine
* Bifeprunox
* BRL-15,572
* Ciprofloxacin
* CSP-2503
* Dapiprazole
* DCPP
* DMPP
* Diphenylpiperazine
* Dropropizine
* EGIS-12,233
* Elopiprazole
* Eltoprazine
* Enpiprazole
* Ensaculin
* Etoperidone
* Flesinoxan
* Fluanisone
* Flibanserin
* Fluprazine
* Itraconazole
* Ketoconazole
* Levodropropizine
* Lorpiprazole
* mCPP
* Mefway
* MeOPP
* Mepiprazole
* Naftopidil
* Naluzotan
* Naphthylpiperazine
* Nefazodone
* Niaprazine
* Oxypertine
* Pardoprunox
* pCPP
* pFPP
* Posaconazole
* S-14,506
* S-14,671
* S-15,535
* SB-258,585
* SB-271,046
* SB-357,134
* SB-399,885
* Sonepiprazole
* TFMPP
* Tolpiprazole
* Trazodone
* Urapidil
* Vesnarinone
* Vilazodone
* Vortioxetine
* WAY-100,135
* WAY-100,635

Benzylpiperazines|

* 2C-B-BZP
* Befuraline
* Bifeprunox
* Buclizine
* BZP
* Chlorbenzoxamine
* DBZP
* Fipexide
* Imatinib
* MBZP
* MDBZP
* Meclozine
* Methoxypiperamide
* Piberaline
* Piribedil
* Sunifiram
* Trimetazidine
* Vesnarinone

Diphenylalkylpiperazines
(benzhydrylalkylpiperazines)|

* AD-1211
* Almitrine
* Amperozide
* BRL-15,572
* Buclizine
* BW373U86
* Cetirizine
* Chlorbenzoxamine
* Chlorcyclizine
* Cinnarizine
* Clocinizine
* Cyclizine
* DBL-583
* Diphenpipenol
* Diphenylmethylpiperazine
* Dotarizine
* DPI-221
* DPI-287
* DPI-3290
* GBR-12,783
* GBR-12,935
* GBR-13,069
* GBR-13,098
* GBR-13,119
* Hydroxyzine
* Lidoflazine
* Manidipine
* Meclozine
* MT-45
* Oxatomide
* SNC-80
* Vanoxerine

Pyrimidinylpiperazines|

* Buspirone
* Dasatinib
* Eptapirone
* Gepirone
* Ipsapirone
* Piribedil
* Prazitone
* Pyrimidinylpiperazine
* Revospirone
* Tandospirone
* Tirilazad
* Trimazosin
* Umespirone
* Zalospirone

Pyridinylpiperazines|

* Atevirdine
* Azaperone
* Delavirdine
* Mirtazapine
* Pyridinylpiperazine

Benzo(iso)thiazolylpiperazines|

* Lurasidone
* Perospirone
* Revospirone
* Tiospirone
* Ziprasidone

Tricyclics
(piperazine attached via side chain)|

* Amoxapine
* Clopenthixol
* Clorotepine
* Clozapine
* Cyanothepin
* Doclothepin
* Docloxythepin
* Flupentixol
* Fluphenazine
* Isofloxythepin
* Loxapine
* Meperathiepin
* Metitepine
* Octomethothepin
* Olanzapine
* Opipramol
* Oxyclothepin
* Oxyprothepin
* Peradithiepin
* Perathiepin
* Perazine
* Perphenazine
* Pirenzepine
* Prochlorperazine
* Thiethylperazine
* Thiothixene
* Trifluoperazine
* Trifluthepin
* Zuclopenthixol

Others/Uncategorized|

* 6-Nitroquipazine
* Azimilide
* Cinepazet
* Cinepazic acid
* Cinepazide
* Cyclohexylpiperazine
* EGIS-7625
* Hexocyclium
* Indinavir
* JNJ-7777120
* Lodenafil
* Mirodenafil
* PB-28
* Quipazine
* Ranolazine
* SA-4503
* Sildenafil
* Tadalafil
* Vardenafil
* VUF-6002
* WY-46824
* Zipeprol

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