1-(2-Chloro-N-methylbenzimidoyl)cyclopentanol

Short description: Chemical compound

1-(2-Chloro-N-methylbenzimidoyl)cyclopentanol

Identifiers

IUPAC name

* 1-[C-(2-chlorophenyl)-N-methylcarbonimidoyl]cyclopentan-1-ol

CAS Number|

* 6740-87-0
* hydrochloride: 90717-16-1

PubChem CID|

* 13086940

ChemSpider|

* 26551984

UNII|

* HGI99H315N

Chemical and physical data
Formula| C13H16ClNO
Molar mass| 237.73 g·mol−1
3D model (JSmol)|

* Interactive image

SMILES

* CN=C(C1=CC=CC=C1Cl)C2(CCCC2)O

InChI

* InChI=1S/C13H16ClNO/c1-15-12(13(16)8-4-5-9-13)10-6-2-3-7-11(10)14/h2-3,6-7,16H,4-5,8-9H2,1H3

* Key:FJGPXUPMNZOTLX-UHFFFAOYSA-N

1-(2-Chloro-N-methylbenzimidoyl)cyclopentanol, sometimes misleadingly referred to as hydroxylimine hydrochloride, is a chemical compound which is the final intermediate in the synthesis of ketamine, an anaesthetic drug which is also subject to recreational abuse. This chemical intermediate is not active as a drug in its own right, and is legal in most countries, but is readily converted into ketamine by dissolving it in a suitable high-boiling point solvent and heating, with no other chemicals required.[1][2] This has made it subject to illicit trade as a drug precursor, and it has sometimes been seized by law enforcement agencies in significant quantities, leading to it being specifically banned as a controlled drug precursor in some jurisdictions such as Taiwan.[3][4]

## See also

* 1-Boc-4-AP
* 1,6-Dioxecane-2,7-dione
* Alprazolam triazolobenzophenone

## References

1. ↑ Stevens CL, "Aminoketones and methods for their production", US patent 3254124, issued 1966-05-31, assigned to Parke Davis & Co.
2. ↑ "Syntheses of Ketamine and Related Analogues: A Mini Review.". Synthesis 50 (21): 4201–4215. 2018. doi:10.1055/s-0037-1609935.
3. ↑ "200 kg of ketamine precursor seized at Taoyuan Airport". Taiwan News. 1 January 2009. https://www.taiwannews.com.tw/en/news/827352.
4. ↑ "Taiwan catches 2 tons of drugs hidden inside machinery from China.". Taiwan News. 31 March 2018. https://www.taiwannews.com.tw/en/news/3395120.

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*[CID]: Compound ID