2-(Ethylamino)-1,2-diphenylethanone

Short description: Chemical compound

2-(Ethylamino)-1,2-diphenylethanone

Clinical data
ATC code|

* None

Identifiers

IUPAC name

* 2-(ethylamino)-1,2-diphenylethanone

CAS Number|

* 22312-16-9 Y

PubChem CID|

* 69702363

UNII|

* 8R3EAH84GZ

Chemical and physical data
Formula| C16H17NO
Molar mass| 239.318 g·mol−1
3D model (JSmol)|

* Interactive image

SMILES

* CCNC(C1=CC=CC=C1)C(=O)C2=CC=CC=C2

InChI

* InChI=1S/C16H17NO/c1-2-17-15(13-9-5-3-6-10-13)16(18)14-11-7-4-8-12-14/h3-12,15,17H,2H2,1H3

* Key:NHNVMSYWZNJBOO-UHFFFAOYSA-N

2-(Ethylamino)-1,2-diphenylethanone (also known as α-ethylamino-deoxybenzoin, [α-(Ethylamino)benzyl]-(phenyl)-ketone and βk-Ephenidine) is a chemical compound which was first invented in 1955,[1] researched by ICI in 1969 as an antidepressant,[2] and subsequently claimed by AstraZeneca as an inhibitor of the enzyme 11β-Hydroxysteroid dehydrogenase type 1.[3] No other pharmacological data has been disclosed, though its chemical structure closely resembles that of certain designer drug compounds such as ephenidine and N-ethylhexedrone.

## See also

* α-PCYP
* Fluorolintane
* Indapyrophenidone
* Lefetamine
* UWA-001

## References

1. ↑ "Über α-Alkylamino-ketone.". Helvetica Chimica Acta 38 (6): 1415–1420. 1955. doi:10.1002/hlca.19550380613.
2. ↑ Gilman DJ, "Desyl amines and compositions thereof. gdate = 19 February 1969", GB patent 1143263, assigned to ICI Ltd.
3. ↑ Barton P, Clarke D, Davies C, Hargreaves R, Pease J, Rankine M, "Ketones", US patent Abandoned 2005272036, published 8 December 2005, assigned to AstraZeneca AB

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*[CID]: Compound ID