Neuropeptide K

Neuropeptide K (also known as neurokinin K[1]), is a protein encoded by the TAC1 gene. It is an elongated derivative of the N-terminus of neurokinin A as the final post-translational processing product of beta-preprotachykinin.[2][3] Like neurokinin A, neuropeptide K has been localized to sensory neurons and likely plays a role in regulating sensation.[3]

While several mammalian brains are shown to express substance P and neurokinin A, they differ on expression of neurokinin A-derived peptides. In contrast with rat and cow brains, the human brain contains larger amounts of neuropeptide K.[4]

## References

1. ↑ "Site-specific effects of intracerebral injections of three neurokinins (neurokinin A, neurokinin K, and neurokinin gamma) on the expression of male rat sexual behavior". Physiol. Behav. 54 (2): 249–58. August 1993. doi:10.1016/0031-9384(93)90107-Q. PMID 7690487.
2. ↑ Takeda, Y; Krause, JE (Jan 1989). "Neuropeptide K potently stimulates salivary gland secretion and potentiates substance P-induced salivation". Proc Natl Acad Sci U S A 86 (1): 392–396. doi:10.1073/pnas.86.1.392. PMID 2463627. Bibcode: 1989PNAS...86..392T.
3. ↑ 3.0 3.1 Holzer, P. (1988-03-01). "Local effector functions of capsaicin-sensitive sensory nerve endings: Involvement of tachykinins, calcitonin gene-related peptide and other neuropeptides". Neuroscience 24 (3): 739–768. doi:10.1016/0306-4522(88)90064-4. PMID 3288903.
4. ↑ Bannon, Michael J.; Poosch, Michael S.; Haverstick, Doris M.; Anita, Mandal; Xue, Iris C. -H.; Shibata, Kazuhiko; Dragovic, Ljubisa J. (1992-01-01). "Preprotachykinin gene expression in the human basal ganglia: characterization of mRNAs and pre-mRNAs produced by alternate RNA splicing". Molecular Brain Research 12 (1–3): 225–231. doi:10.1016/0169-328X(92)90088-S. PMID 1312203.

* v
* t
* e

Peptides: neuropeptides

Hormones|

see hormones

Opioid peptides|

| Dynorphins|

* Dynorphin A
* Dynorphin A1–8
* Dynorphin B
* Big dynorphin
* Leumorphin
* α-Neoendorphin
* β-Neoendorphin

|

Endomorphins|

* Endomorphin-1
* Endomorphin-2

Endorphins|

* α-Endorphin
* β-Endorphin
* γ-Endorphin

Enkephalins|

* Met-enkephalin
* Leu-enkephalin

Others|

* Adrenorphin
* Amidorphin
* Hemorphin
* Hemorphin-4
* Nociceptin
* Opiorphin
* Spinorphin
* Valorphin

Other
neuropeptides|

| Kinins|

Bradykinins
Tachykinins: mammal

* Substance P
* Neurokinin A
* Neurokinin B

amphibian

* Kassinin
* Physalaemin

|

Neuromedins|

* B
* N
* S
* U

Orexins|

* A
* B

Other|

* Angiotensin
* Bombesin
* Calcitonin gene-related peptide
* Carnosine
* Cocaine- and amphetamine-regulated transcript
* Delta sleep-inducing peptide
* FMRFamide
* Galanin
* Galanin-like peptide
* Gastrin-releasing peptide
* Ghrelin
* Neuropeptide AF
* Neuropeptide FF
* Neuropeptide SF
* Neuropeptide VF
* Neuropeptide S
* Neuropeptide Y
* Neurophysins
* Neurotensin
* Pancreatic polypeptide
* Pituitary adenylate cyclase-activating peptide
* RVD-Hpα
* VGF

* v
* t
* e

Autacoids

Kinins|

* Kininogen (HMWK, Low-molecular-weight kininogen

Others|

* Angiotensin
* Eicosanoid
* Histamine
* Platelet-activating factor
* Serotonin

0.00

(0 votes)

Original source: https://en.wikipedia.org/wiki/Neuropeptide K. Read more

|

Retrieved from "https://handwiki.org/wiki/index.php?title=Biology:Neuropeptide_K&oldid=409592"
*[v]: View this template
*[t]: Discuss this template
*[e]: Edit this template