Acetic acid (medical use)

Short description: Medical uses of acetic acid or vinegar

Acetic acid

Chemical formula of acetic acid

Clinical data
Pronunciation| a-SEE-tik
Trade names| Acetasol, Vasotate, Domeboro Otic, others
Other names| Vinegar
AHFS/Drugs.com| Monograph
License data|

* US DailyMed: Acetic_acid

Routes of
administration| ear drops, irrigation, by mouth
ATC code|

* S02AA10 (WHO)

Legal status
Legal status|

* US: ℞-only / OTC

Identifiers

IUPAC name

* acetic acid

CAS Number|

* 64-19-7

PubChem CID|

* 176

DrugBank|

* DB03166

ChemSpider|

* 171

UNII|

* Q40Q9N063P

KEGG|

* D00010
* C00033

ChEBI|

* CHEBI:15366

ChEMBL|

* ChEMBL539

PDB ligand|

* ACY (PDBe, RCSB PDB)

Chemical and physical data
Formula| C2H4O2
Molar mass| 60.052 g·mol−1
3D model (JSmol)|

* Interactive image

SMILES

* CC(=O)O

InChI

* InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)

* Key:QTBSBXVTEAMEQO-UHFFFAOYSA-N

Acetic acid, which at low concentrations is known as vinegar, is an acid used to treat a number of conditions.

## Contents

* 1 Definition and medical uses
* 2 History and culture
* 3 References
* 4 External links

## Definition and medical uses

As an eardrop it is used to treat infections of the ear canal.[1] It may be used with an ear wick.[2] As a liquid it is used to flush the bladder in those who have a urinary catheter in an attempt to prevent infection or blockage.[3] As a gel it may be used to adjust the pH of the vagina.[4] It may also be applied to the cervix to help detect cervical cancer during screening.[5]

Side effects may include burning at the site of application.[6] Allergic reactions may rarely occur.[6] Use is not recommended in the ear in people who have a hole in the eardrum.[7] It works against both bacterial and fungal causes of external ear infections.[7]

## History and culture

Acetic acid has been used medically since the time of Ancient Egypt.[8][9] It is on the World Health Organization's List of Essential Medicines.[10] Acetic acid is more commonly used for external ear infections in the developing world than the developed.[11]

## References

1. ↑ "Acetic acid (otic) medical facts from Drugs.com". https://www.drugs.com/mtm/acetic-acid-otic.html.
2. ↑ Hamilton, Richart (2015). Tarascon Pocket Pharmacopoeia 2015 Deluxe Lab-Coat Edition. Jones & Bartlett Learning. p. 252. ISBN 9781284057560.
3. ↑ "Acetic Acid". The American Society of Health-System Pharmacists. https://www.drugs.com/monograph/acetic-acid.html.
4. ↑ "Acetic acid gel: Indications, Side Effects, Warnings - Drugs.com". https://www.drugs.com/cdi/acetic-acid-gel.html.
5. ↑ "Performance of alternative strategies for primary cervical cancer screening in sub-Saharan Africa: systematic review and meta-analysis of diagnostic test accuracy studies". BMJ 351: h3084. July 2015. doi:10.1136/bmj.h3084. PMID 26142020.
6. ↑ 6.0 6.1 "Acetic acid otic Side Effects in Detail - Drugs.com". https://www.drugs.com/sfx/acetic-acid-otic-side-effects.html.
7. ↑ 7.0 7.1 "Acetic Acid - FDA prescribing information, side effects and uses". https://www.drugs.com/pro/acetic-acid.html.
8. ↑ "Supplements: Use Often for Health" (in en). The Beginner's Guide to Natural Living: How to Cultivate a More Natural Lifestyle to Lose Weight, Prevent Degenerative Disease, Improve Your Energy and Attain Vibrant Health. EcoVision Communications. 2005. p. 107. ISBN 9780975536186. https://books.google.com/books?id=9_h08MyyjVMC&pg=PA107.
9. ↑ "Hindu Medicine. Chaldean And Persian Medicine" (in en). The History of Medicine. Routledge. 2013. p. Chapter 2. ISBN 9781136194252. https://books.google.com/books?id=Obb7AQAAQBAJ&pg=PT69.
10. ↑ World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. 2019. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
11. ↑ "Ear Pain and Cerumen Impaction" (in en). Primary Care for Emergency Physicians. Springer. 2016. p. 36. ISBN 9783319443607. https://books.google.com/books?id=1DOgDQAAQBAJ&pg=PA36.

## External links

* "Acetic acid". Drug Information Portal. U.S. National Library of Medicine. https://druginfo.nlm.nih.gov/drugportal/name/acetic acid.

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*[US]: United States
*[CID]: Compound ID