Acetophenone carboxylase

Short description: Class of enzymes

Acetophenone carboxylase

Identifiers
EC number| 6.4.1.8
Databases
IntEnz| IntEnz view
BRENDA| BRENDA entry
ExPASy| NiceZyme view
KEGG| KEGG entry
MetaCyc| metabolic pathway
PRIAM| profile
PDB structures| RCSB PDB PDBe PDBsum
| Search

PMC| articles
PubMed| articles
NCBI| proteins

Acetophenone carboxylase (EC 6.4.1.8) is an enzyme with systematic name acetophenone:carbon-dioxide ligase (ADP-forming).[1] This enzyme catalyses the following chemical reaction

2 ATP + acetophenone + HCO3− \+ H2O + H+ ⇌ 2 ADP + 2 phosphate \+ 3-oxo-3-phenylpropanoate

The enzyme is involved in anaerobic degradation of ethylbenzene.

## References

1. ↑ "ATP-dependent carboxylation of acetophenone by a novel type of carboxylase". Journal of Bacteriology 192 (5): 1387–94. March 2010. doi:10.1128/jb.01423-09. PMID 20047908.

## External links

* Acetophenone+carboxylase at the US National Library of Medicine Medical Subject Headings (MeSH)

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Ligases: carbon-carbon ligases (EC 6.4)

Biotin dependent carboxylation|

* Pyruvate carboxylase
* Acetyl-CoA carboxylase
* Propionyl-CoA carboxylase
* Methylcrotonyl-CoA carboxylase

Other|

* Polyketide synthase

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Enzymes

Activity|

* Active site
* Binding site
* Catalytic triad
* Oxyanion hole
* Enzyme promiscuity
* Catalytically perfect enzyme
* Coenzyme
* Cofactor
* Enzyme catalysis

Regulation|

* Allosteric regulation
* Cooperativity
* Enzyme inhibitor
* Enzyme activator

Classification|

* EC number
* Enzyme superfamily
* Enzyme family
* List of enzymes

Kinetics|

* Enzyme kinetics
* Eadie–Hofstee diagram
* Hanes–Woolf plot
* Lineweaver–Burk plot
* Michaelis–Menten kinetics

Types|

* EC1 Oxidoreductases (list)
* EC2 Transferases (list)
* EC3 Hydrolases (list)
* EC4 Lyases (list)
* EC5 Isomerases (list)
* EC6 Ligases (list)
* EC7 Translocases (list)

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