Reactive gastropathy

Micrograph of a reactive gastropathy. H&E stain.
Specialty| Pathology, gastroenterology

Reactive gastropathy, chemical gastropathy also called gastritis of « C type » or "chemical gastritis"[1] is an abnormality in the stomach caused by chemicals, e.g. bile, alcohol, and characteristically has minimal inflammation.

## Contents

* 1 Cause
* 2 Diagnosis
* 3 Relation to gastritis
* 4 See also
* 5 References
* 6 External links

## Cause

Reactive gastropathy has a large number of causes, including:

* Alcohol use disorder.
* Bile reflux, such as may be seen post-Billroth II.
* NSAIDs.

## Diagnosis

Reactive gastropathy, is characterized histologically by:[2]
\- Foveolar hyperplasia (black arrow), as a tortuosity in the "neck" region of the gastric glands.
\- Scant or minimal inflammatory cells (white arrow), i.e. lack of large numbers of neutrophils and plasma cells..
\- Smooth muscle hyperplasia in the lamina propria (in black oval).

The diagnosis is by examination of tissue, e.g. a stomach biopsy.

* Low mag.

* High mag.

## Relation to gastritis

Reactive gastropathy is morphologically distinct entity[3][4] that can be separated from gastritis, which by definition has a significant inflammatory component.

As a reactive gastropathy may mimic a (true) gastritis symptomatically and visually in an endoscopic examination, it may incorrectly be referred to as a gastritis. Even aware of the underlying etiology of the pathologic process, e.g. NSAID use, the label "chemical gastritis" is applied to a chemical gastropathy.

## See also

* Gastritis

## References

1. ↑ "Chronic gastritis—a pathogenesis approach". The Journal of Pathology 40 (154): 113–24. 1988. doi:10.1002/path.1711540203. PMID 3280764.
2. ↑ Genta, RM (Nov 2005). "Differential diagnosis of reactive gastropathy". Seminars in Diagnostic Pathology 22 (4): 273–83. doi:10.1053/j.semdp.2006.04.001. PMID 16939055.
3. ↑ Pashankar, DS; Bishop, WP; Mitros, FA (Nov 2002). "Chemical gastropathy: a distinct histopathologic entity in children". Journal of Pediatric Gastroenterology and Nutrition 35 (5): 653–7. doi:10.1097/00005176-200211000-00012. PMID 12454581.
4. ↑ Dixon, MF; O'Connor, HJ; Axon, AT; King, RF; Johnston, D (May 1986). "Reflux gastritis: distinct histopathological entity?". Journal of Clinical Pathology 39 (5): 524–30. doi:10.1136/jcp.39.5.524. PMID 3722405.

## External links

Classification|

|

External resources|

* eMedicine: article/1962893

* Reactive gastropathy - surgical pathology criteria (stanford.edu).

* v
* t
* e

Diseases of the digestive system (primarily K20–K93, 530–579)

Upper GI tract|

| Esophagus|

* Esophagitis
* Candidal
* Eosinophilic
* Herpetiform
* Rupture
* Boerhaave syndrome
* Mallory–Weiss syndrome
* UES
* Zenker's diverticulum
* LES
* Barrett's esophagus
* Esophageal motility disorder
* Nutcracker esophagus
* Achalasia
* Diffuse esophageal spasm
* Gastroesophageal reflux disease (GERD)
* Laryngopharyngeal reflux (LPR)
* Esophageal stricture
* Megaesophagus

|

Stomach|

* Gastritis
* Atrophic
* Ménétrier's disease
* Gastroenteritis
* Peptic (gastric) ulcer
* Cushing ulcer
* Dieulafoy's lesion
* Dyspepsia
* Pyloric stenosis
* Achlorhydria
* Gastroparesis
* Gastroptosis
* Portal hypertensive gastropathy
* Gastric antral vascular ectasia
* Gastric dumping syndrome
* Gastric volvulus
* Buried bumper syndrome

Lower GI tract:
Intestinal/
Enteropathy|

| Small intestine
(Duodenum/Jejunum/Ileum)|

* Enteritis
* Duodenitis
* Jejunitis
* Ileitis
* Peptic (duodenal) ulcer
* Curling's ulcer
* Malabsorption: Coeliac
* Tropical sprue
* Blind loop syndrome
* Small bowel bacterial overgrowth syndrome
* Whipple's
* Short bowel syndrome
* Steatorrhea
* Milroy disease
* Bile acid malabsorption

|

Large intestine
(Appendix/Colon)|

* Appendicitis
* Colitis
* Pseudomembranous
* Ulcerative
* Ischemic
* Microscopic
* Collagenous
* Lymphocytic
* Functional colonic disease
* IBS
* Intestinal pseudoobstruction / Ogilvie syndrome
* Megacolon / Toxic megacolon
* Diverticulitis/Diverticulosis

Large and/or small|

* Enterocolitis
* Necrotizing
* Gastroenterocolitis
* IBD
* Crohn's disease
* Vascular: Abdominal angina
* Mesenteric ischemia
* Angiodysplasia
* Bowel obstruction: Ileus
* Intussusception
* Volvulus
* Fecal impaction
* Constipation
* Diarrhea
* Infectious
* Intestinal adhesions

Rectum|

* Proctitis
* Radiation proctitis
* Proctalgia fugax
* Rectal prolapse
* Anismus

Anal canal|

* Anal fissure/Anal fistula
* Anal abscess
* Hemorrhoid
* Anal dysplasia
* Pruritus ani

GI bleeding/BIS|

* Upper
* Hematemesis
* Melena
* Lower
* Hematochezia

Accessory|

| Liver|

* Hepatitis
* Viral hepatitis
* Autoimmune hepatitis
* Alcoholic hepatitis
* Cirrhosis
* PBC
* Fatty liver
* NASH
* Vascular
* Budd–Chiari syndrome
* Hepatic veno-occlusive disease
* Portal hypertension
* Nutmeg liver
* Alcoholic liver disease
* Liver failure
* Hepatic encephalopathy
* Acute liver failure
* Liver abscess
* Pyogenic
* Amoebic
* Hepatorenal syndrome
* Peliosis hepatis
* Metabolic disorders
* Wilson's disease
* Hemochromatosis

|

Gallbladder|

* Cholecystitis
* Gallstones/Cholecystolithiasis
* Cholesterolosis
* Adenomyomatosis
* Postcholecystectomy syndrome
* Porcelain gallbladder

Bile duct/
Other biliary tree|

* Cholangitis
* Primary sclerosing cholangitis
* Secondary sclerosing cholangitis
* Ascending
* Cholestasis/Mirizzi's syndrome
* Biliary fistula
* Haemobilia
* Gallstones/Cholelithiasis

* Common bile duct
* Choledocholithiasis
* Biliary dyskinesia
* Sphincter of Oddi dysfunction

Pancreatic|

* Pancreatitis
* Acute
* Chronic
* Hereditary
* Pancreatic abscess
* Pancreatic pseudocyst
* Exocrine pancreatic insufficiency
* Pancreatic fistula

Abdominopelvic|

| Hernia|

* Diaphragmatic
* Congenital
* Hiatus

* Inguinal
* Indirect
* Direct
* Umbilical
* Femoral
* Obturator
* Spigelian

* Lumbar
* Petit's
* Grynfeltt-Lesshaft

* Undefined location
* Incisional
* Internal hernia
* Richter's

|

Peritoneal|

* Peritonitis
* Spontaneous bacterial peritonitis
* Hemoperitoneum
* Pneumoperitoneum

* v
* t
* e

Inflammation

Acute|

| Plasma-derived mediators|

* Bradykinin
* complement
* C3
* C5a
* MAC
* coagulation
* Factor XII
* Plasmin
* Thrombin

|

Cell-derived mediators|

| preformed:|

* Lysosome granules
* biogenic amines
* Histamine
* Serotonin

|

synthesized on demand:|

* cytokines
* IFN-γ
* IL-8
* TNF-α
* IL-1
* eicosanoids
* Leukotriene B4
* Prostaglandins
* Nitric oxide
* Kinins

Chronic|

* Macrophage
* Epithelioid cell
* Giant cell
* Granuloma

Processes|

| Traditional|

* Rubor
* Calor
* Tumor
* Dolor
* Functio laesa

|

Modern|

* Acute-phase reaction/Fever
* Vasodilation
* Increased vascular permeability
* Exudate
* Leukocyte extravasation
* Chemotaxis

Specific
locations|

| Nervous|

* CNS
* Encephalitis
* Myelitis
* Meningitis
* Arachnoiditis
* PNS
* Neuritis
* eye
* Dacryoadenitis
* Scleritis
* Episcleritis
* Keratitis
* chorioretinitis
* Retinitis
* Chorioretinitis
* Blepharitis
* Conjunctivitis
* Uveitis
* ear
* Otitis externa
* Otitis media
* Labyrinthitis
* Mastoiditis

|

Cardiovascular|

* Carditis
* Endocarditis
* Myocarditis
* Pericarditis
* Vasculitis
* Arteritis
* Phlebitis
* Capillaritis

Respiratory|

* upper
* Sinusitis
* Rhinitis
* Pharyngitis
* Laryngitis
* lower
* Tracheitis
* Bronchitis
* Bronchiolitis
* Pneumonitis
* Pleuritis
* Mediastinitis

Digestive|

| mouth|

* Stomatitis
* Gingivitis
* Gingivostomatitis
* Glossitis
* Tonsillitis
* Sialadenitis/Parotitis
* Cheilitis
* Pulpitis
* Gnathitis

|

tract|

* Esophagitis
* Gastritis
* Gastroenteritis
* Enteritis
* Colitis
* Enterocolitis
* Duodenitis
* Ileitis
* Caecitis
* Appendicitis
* Proctitis

accessory|

* Hepatitis
* Ascending cholangitis
* Cholecystitis
* Pancreatitis
* Peritonitis

Integumentary|

* Dermatitis
* Folliculitis
* Cellulitis
* Hidradenitis

Musculoskeletal|

* Arthritis
* Dermatomyositis
* soft tissue
* Myositis
* Synovitis/Tenosynovitis
* Bursitis
* Enthesitis
* Fasciitis
* Capsulitis
* Epicondylitis
* Tendinitis
* Panniculitis
* Osteochondritis: Osteitis/Osteomyelitis
* Spondylitis
* Periostitis
* Chondritis

Urinary|

* Nephritis
* Glomerulonephritis
* Pyelonephritis
* Ureteritis
* Cystitis
* Urethritis

Reproductive|

| female|

* Oophoritis
* Salpingitis
* Endometritis
* Parametritis
* Cervicitis
* Vaginitis
* Vulvitis
* Mastitis

|

male|

* Orchitis
* Epididymitis
* Prostatitis
* Seminal vesiculitis
* Balanitis
* Posthitis
* Balanoposthitis

pregnancy/newborn|

* Chorioamnionitis
* Funisitis
* Omphalitis

Endocrine|

* Insulitis
* Hypophysitis
* Thyroiditis
* Parathyroiditis
* Adrenalitis

Lymphatic|

* Lymphangitis
* Lymphadenitis

0.00

(0 votes)

Original source: https://en.wikipedia.org/wiki/Reactive gastropathy. Read more

|

Retrieved from "https://handwiki.org/wiki/index.php?title=Medicine:Reactive_gastropathy&oldid=4240108"
*[v]: View this template
*[t]: Discuss this template
*[e]: Edit this template