Pharyngeal pouch (embryology)

Pharyngeal pouch

Pattern of the branchial arches. I-IV branchial arches, 1–4 pharyngeal pouches (inside) and/or pharyngeal grooves (outside)
a Tuberculum laterale
b Tuberculum impar
c Foramen cecum
d Ductus thyreoglossus
e Sinus cervicalis

Floor of pharynx of human embryo about twenty-six days old.

Details
Carnegie stage| 10
Identifiers
Latin| sacci pharyngei
Anatomical terminology

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In the embryonic development of vertebrates, pharyngeal pouches form on the endodermal side between the pharyngeal arches. The pharyngeal grooves (or clefts) form the lateral ectodermal surface of the neck region to separate the arches.

## Contents

* 1 Specific pouches
* 1.1 First pouch
* 1.2 Second pouch
* 1.3 Third pouch
* 1.4 Fourth pouch
* 1.5 Fifth pouch
* 1.6 Sixth pouch
* 2 See also
* 3 References
* 4 External links

## Specific pouches

### First pouch

The endoderm lines the future auditory tube (Pharyngotympanic Eustachian tube), middle ear, mastoid antrum, and inner layer of the tympanic membrane. Derivatives of this pouch are supplied by Mandibular nerve.

### Second pouch

* Contributes the middle ear, palatine tonsils, supplied by the facial nerve.

### Third pouch

* The third pouch possesses Dorsal and Ventral wings. Derivatives of the dorsal wings include the inferior parathyroid glands, while the ventral wings fuse to form the cytoreticular cells of the thymus. The main nerve supply to the derivatives of this pouch is Cranial Nerve IX, glossopharyngeal nerve.

### Fourth pouch

Derivatives include:

* superior parathyroid glands and ultimobranchial body which forms the parafollicular C-Cells of the thyroid gland.
* Musculature and cartilage of larynx (along with the sixth pharyngeal arch).
* Nerve supplying these derivatives is Superior laryngeal nerve.

### Fifth pouch

* Rudimentary structure, becomes part of the fourth pouch contributing to thyroid C-cells.[1]

### Sixth pouch

* The fourth and sixth pouches contribute to the formation of the musculature and cartilage of the larynx. Nerve supply is by the recurrent laryngeal nerve.

## See also

* Pharyngeal arch (often called branchial arch although this is more specifically a fish structure)
* DiGeorge syndrome
* List of human cell types derived from the germ layers

## References

1. ↑ Endocrine Glands

## External links

* Swiss embryology (from UL, UB, and UF) rrespiratory/korperhohlen01 (Item #1 at Fig. 14)
* hednk-021—Embryo Images at University of North Carolina
* hednk-022—Embryo Images at University of North Carolina
* Outline at howard.edu (scroll down to "III. THE PHARYNGEAL POUCHES")

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Development of the head and neck

Face|

* Nasal placode
* Nasal pit
* Nasal prominences
* Lateral
* Medial
* Intermaxillary segment
* Frontonasal prominence
* Maxillary prominence
* Mandibular prominence
* Meckel's cartilage

Mouth|

| Palate|

* Primary palate
* Secondary palate

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Tongue|

* Lateral lingual swelling
* Median tongue bud
* Copula linguae
* Hypopharyngeal eminence
* Gustatory placode

General|

* Pharyngeal apparatus
* Pharyngeal groove
* Cervical sinus
* Pharyngeal arch
* Pharyngeal pouch

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