Galmic

Short description: Chemical compound

Galmic

Identifiers
PubChem CID|

* 11636593

ChemSpider|

* 25046661 N

ChEMBL|

* ChEMBL578918 N

Chemical and physical data
Formula| C51H60N10O11
Molar mass| 989.080 g·mol−1
3D model (JSmol)|

* Interactive image

SMILES

* c7cccc3c7-c4ccccc4C3NC(=O)C(C)(c(oc6C)nc6C(=O)NC2(C)C(=O)NC(C(=O)OC)CCCCN)NC(=O)c1nc(oc1C)C(C)(NC(=O)c5nc2oc5C)C(=O)NCC8CCCCC8

InChI

* InChI=1S/C51H60N10O11/c1-26-36-41(64)61-51(6,45(68)55-38-32-21-13-11-19-30(32)31-20-12-14-22-33(31)38)48-58-37(28(3)72-48)40(63)60-50(5,44(67)54-34(42(65)69-7)23-15-16-24-52)47-57-35(27(2)71-47)39(62)59-49(4,46(56-36)70-26)43(66)53-25-29-17-9-8-10-18-29/h11-14,19-22,29,34,38H,8-10,15-18,23-25,52H2,1-7H3,(H,53,66)(H,54,67)(H,55,68)(H,59,62)(H,60,63)(H,61,64)/t34-,49-,50-,51-/m0/s1 N

NY (what is this?) (verify)

Galmic is a drug which acts as a selective, non-peptide agonist at the galanin receptors GALR.[1] It has anticonvulsant, antidepressant and analgesic effects in animal studies,[2] but also inhibits memory functions.[3]

## References

1. ↑ "Synthesis of galmic: a nonpeptide galanin receptor agonist". Proceedings of the National Academy of Sciences of the United States of America 101 (48): 16727–32. November 2004. doi:10.1073/pnas.0407543101. PMID 15557002. Bibcode: 2004PNAS..10116727C.
2. ↑ "Galmic, a nonpeptide galanin receptor agonist, affects behaviors in seizure, pain, and forced-swim tests". Proceedings of the National Academy of Sciences of the United States of America 101 (28): 10470–5. July 2004. doi:10.1073/pnas.0403802101. PMID 15240875. Bibcode: 2004PNAS..10110470B.
3. ↑ "Effect of galnon on induction of long-term potentiation in dentate gyrus of C57BL/6 mice". Neuropeptides 39 (3): 249–51. June 2005. doi:10.1016/j.npep.2004.12.010. PMID 15944018.

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*[CID]: Compound ID