List of adverse effects of venlafaxine

The following list shows the rates of adverse symptoms seen in people taking venlafaxine.[1][2][3]

## Contents

* 1 Very common (>10% incidence)
* 2 Common (1–10% incidence)
* 3 Uncommon (0.1-1% incidence)
* 4 Rare (0.01–0.1% incidence)
* 5 Very rare (<0.01% incidence)
* 6 References

## Very common (>10% incidence)[edit | edit source]

* Headache — an often transient side effect that is common to most serotonin reuptake inhibitors and that most often occurs at the beginning of therapy or after a dose escalation.
* Nausea — an adverse effect that is more common with venlafaxine than with the SSRIs. Usually transient and less severe in those receiving the extended release formulations.
* Insomnia
* Asthenia (weakness)
* Dizziness
* Ejaculation disorder — sexual side effects can be seen with virtually any antidepressant, especially those that inhibit the reuptake of serotonin (including venlafaxine).[4]
* Somnolence
* Dry mouth
* Sweating
* Withdrawal

## Common (1–10% incidence)[edit | edit source]

* Constipation
* Nervousness
* Abnormal vision
* Anorgasmia
* Hypertension
* Impotence
* Paresthesia
* Tremor
* Vasodilation
* Vomiting
* Weight loss
* Chills
* Palpitations
* Confusion
* Depersonalisation
* Night sweats
* Menstrual disorders associated with increased bleeding or increased irregular bleeding (e.g. menorrhagia, metrorrhagia)
* Urinary frequency increased
* Abnormal dreams
* Decreased libido
* Increased muscle tonus
* Yawning
* Sweating
* Abnormality of accommodation
* Abnormal ejaculation/orgasm (males)
* Urinary hesitancy
* Serum cholesterol increased (especially when treatment is prolonged and it may be dose-dependent)

## Uncommon (0.1-1% incidence)[edit | edit source]

* Face edema
* Intentional injury (self-injury)
* Malaise
* Moniliasis
* Neck rigidity
* Pelvic pain
* Photosensitivity reaction
* Suicide attempt
* Withdrawal syndrome
* Hypotension
* Postural hypotension
* Syncope
* Tachycardia
* Bruxism
* Ecchymosis
* Mucous membrane bleeding
* Gastrointestinal bleeding
* Abnormal liver function tests
* Hyponatraemia
* Weight gain
* Apathy
* Hallucinations
* Myoclonus
* Rash
* Abnormal orgasm (females)
* Urinary retention (the inability to pass urine)
* Angioedema
* Agitation
* Impaired coordination & balance
* Alopecia (hair loss)
* Tinnitus (hearing bells)
* Proteinuria (protein in urine)

## Rare (0.01–0.1% incidence)[edit | edit source]

* Syndrome of inappropriate antidiuretic hormone secretion (SIADH)
* Thrombocytopenia
* Prolonged bleeding time
* Seizures
* Mania
* Neuroleptic malignant syndrome (NMS)
* Serotonin syndrome
* Akathisia/psychomotor restlessness
* Urinary incontinence

## Very rare (<0.01% incidence)[edit | edit source]

* Anaphylaxis
* QT prolongation
* Ventricular fibrillation
* Ventricular tachycardia (including torsades de pointes)
* Pancreatitis
* Blood dyscrasias (including agranulocytosis, aplastic anaemia, neutropenia and pancytopenia)
* Elevated serum prolactin
* Delirium
* Extrapyramidal reactions (including dystonia and dyskinesia)
* Tardive dyskinesia
* Pulmonary eosinophilia
* Erythema multiforme
* Stevens–Johnson syndrome
* Pruritus
* Urticaria
* Toxic epidermal necrolysis
* Angle closure glaucoma

## References[edit | edit source]

1. ↑ "APO-VENLAFAXINE XR CAPSULES" (PDF). TGA eBusiness Services. Macquarie Park, NSW: Apotex Pty Ltd. 13 April 2012. Archived from the original on 19 April 2018. Retrieved 6 November 2013.
2. ↑ "VENLAFAXINE (venlafaxine hydrochloride) tablet [Aurobindo Pharma Limited]". DailyMed. Aurobindo Pharma Limited. February 2013. Archived from the original on 30 January 2020. Retrieved 6 November 2013.
3. ↑ "Effexor, Effexor XR (venlafaxine) dosing, indications, interactions, adverse effects, and more". Medscape Reference. WebMD. Archived from the original on 19 December 2013. Retrieved 6 November 2013.
4. ↑ David Taylor; Carol Paton; Shitij Kapur, eds. (2012). The Maudsley Prescribing Guidelines in Psychiatry (illustrated ed.). John Wiley & Sons. ISBN 978-0-470-97948-8.