diamine transaminase

Identifiers
EC number| 2.6.1.29
CAS number| 9031-83-8
Databases
IntEnz| IntEnz view
BRENDA| BRENDA entry
ExPASy| NiceZyme view
KEGG| KEGG entry
MetaCyc| metabolic pathway
PRIAM| profile
PDB structures| RCSB PDB PDBe PDBsum
Gene Ontology| AmiGO  / QuickGO
| Search

PMC| articles
PubMed| articles
NCBI| proteins

In enzymology, a diamine transaminase (EC 2.6.1.29) is an enzyme that catalyzes the chemical reaction:

an alpha,omega-diamine + 2-oxoglutarate ⇌ an omega-aminoaldehyde + L-glutamate

Thus, the two substrates of this enzyme are alpha,omega-diamine and 2-oxoglutarate, whereas its two products are omega-aminoaldehyde and L-glutamate.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is diamine:2-oxoglutarate aminotransferase. Other names in common use include amine transaminase, amine-ketoacid transaminase, diamine aminotransferase, and diamine-ketoglutaric transaminase. This enzyme participates in urea cycle and metabolism of amino groups.

## References

* "Purification and properties of a diamine alpha-ketoglutarate transaminase from Escherichia coli". J. Biol. Chem. 239 (3): 783-786. 1964. doi:10.1016/S0021-9258(18)51659-8.

* v
* t
* e

Transferase: nitrogenous groups (EC 2.6)

2.6.1: Transaminases|

* Aspartate transaminase
* GOT1
* GOT2
* Alanine transaminase
* GABA transaminase
* Tyrosine aminotransferase
* Kynurenine—oxoglutarate transaminase
* Ornithine aminotransferase
* Branched-chain amino acid aminotransferase
* Alanine—glyoxylate transaminase
* AGXT

2.6.3: Oximinotransferases|

* Oximinotransferase

2.6.99: Other|

* Pyridoxine 5'-phosphate synthase

* v
* t
* e

Enzymes

Activity|

* Active site
* Binding site
* Catalytic triad
* Oxyanion hole
* Enzyme promiscuity
* Catalytically perfect enzyme
* Coenzyme
* Cofactor
* Enzyme catalysis

Regulation|

* Allosteric regulation
* Cooperativity
* Enzyme inhibitor
* Enzyme activator

Classification|

* EC number
* Enzyme superfamily
* Enzyme family
* List of enzymes

Kinetics|

* Enzyme kinetics
* Eadie–Hofstee diagram
* Hanes–Woolf plot
* Lineweaver–Burk plot
* Michaelis–Menten kinetics

Types|

* EC1 Oxidoreductases (list)
* EC2 Transferases (list)
* EC3 Hydrolases (list)
* EC4 Lyases (list)
* EC5 Isomerases (list)
* EC6 Ligases (list)
* EC7 Translocases (list)

0.00

(0 votes)

Original source: https://en.wikipedia.org/wiki/Diamine transaminase. Read more

|

Retrieved from "https://handwiki.org/wiki/index.php?title=Biology:Diamine_transaminase&oldid=4043785"
*[v]: View this template
*[t]: Discuss this template
*[e]: Edit this template