Nanoparticle

Short description: Particle with size less than 100 nm

TEM (a, b, and c) images of prepared mesoporous silica nanoparticles with mean outer diameter: (a) 20nm, (b) 45nm, and (c) 80nm. SEM (d) image corresponding to (b). The insets are a high magnification of mesoporous silica particle. Part of a series of articles on

Nanomaterials
Carbon nanotubes

* Synthesis
* Chemistry
* Mechanical properties
* Optical properties
* Applications
* Timeline

Fullerenes

* Buckminsterfullerene
* C70 fullerene
* Chemistry
* Health impact
* Carbon allotropes

Other nanoparticles

* Quantum dots
* Aluminium oxide
* Cellulose
* Ceramic
* Cobalt oxide
* Copper
* Gold
* Iron
* Iron oxide
* Iron–platinum
* Lipid
* Platinum
* Silver
* Titanium dioxide

Nanostructured materials

* Nanocomposite
* Nanofoam
* Nanoporous materials
* Nanocrystalline material

*   *

* v
* t
* e

A nanoparticle or ultrafine particle is a particle of matter 1 to 100 nanometres (nm) in diameter.[1][2] The term is sometimes used for larger particles, up to 500 nm, or fibers and tubes that are less than 100 nm in only two directions.[2]: 394 At the lowest range, metal particles smaller than 1 nm are usually called atom clusters instead.

Nanoparticles are distinguished from microparticles (1–1000 μm), "fine particles" (sized between 100 and 2500 nm), and "coarse particles" (ranging from 2500 to 10,000 nm), because their smaller size drives very different physical or chemical properties, like colloidal properties and ultrafast optical effects[3] or electric properties.

Being more subject to the Brownian motion, they usually do not sediment, like colloidal particles that conversely are usually understood to range from 1 to 1000 nm.

Being much smaller than the wavelengths of visible light (400–700 nm), nanoparticles cannot be seen with ordinary optical microscopes, requiring the use of electron microscopes or microscopes with laser. For the same reason, dispersions of nanoparticles in transparent media can be transparent,[4] whereas suspensions of larger particles usually scatter some or all visible light incident on them. Nanoparticles also easily pass through common filters, such as common ceramic candles,[5] so that separation from liquids requires special nanofiltration techniques.

The properties of nanoparticles often differ markedly from those of larger particles of the same substance. Since the typical diameter of an atom is between 0.15 and 0.6 nm, a large fraction of the nanoparticle's material lies within a few atomic diameters of its surface. Therefore, the properties of that surface layer may dominate over those of the bulk material. This effect is particularly strong for nanoparticles dispersed in a medium of different composition since the interactions between the two materials at their interface also becomes significant.[6]

Idealized model of a crystalline nanoparticle of platinum, about 2 nm in diameter, showing individual atoms.

Nanoparticles occur widely in nature and are objects of study in many sciences such as chemistry, physics, geology, and biology. Being at the transition between bulk materials and atomic or molecular structures, they often exhibit phenomena that are not observed at either scale. They are an important component of atmospheric pollution, and key ingredients in many industrialized products such as paints, plastics, metals, ceramics, and magnetic products. The production of nanoparticles with specific properties is a branch of nanotechnology.

In general, the small size of nanoparticles leads to a lower concentration of point defects compared to their bulk counterparts,[7] but they do support a variety of dislocations that can be visualized using high-resolution electron microscopes.[8] However, nanoparticles exhibit different dislocation mechanics, which, together with their unique surface structures, results in mechanical properties that are different from the bulk material.[9][10][11]

Non-spherical nanoparticles (e.g., prisms, cubes, rods etc.) exhibit shape-dependent and size-dependent (both chemical and physical) properties (anisotropy).[12][13] Non-spherical nanoparticles of gold (Au), silver (Ag), and platinum (Pt) due to their fascinating optical properties are finding diverse applications. Non-spherical geometries of nanoprisms give rise to high effective cross-sections and deeper colors of the colloidal solutions.[14] The possibility of shifting the resonance wavelengths by tuning the particle geometry allows using them in the fields of molecular labeling, biomolecular assays, trace metal detection, or nanotechnical applications. Anisotropic nanoparticles display a specific absorption behavior and stochastic particle orientation under unpolarized light, showing a distinct resonance mode for each excitable axis.[14]

## Contents

* 1 Definitions
* 1.1 International Union of Pure and Applied Chemistry (IUPAC)
* 1.2 International Organization for Standardization (ISO)
* 1.3 Common usage
* 1.4 Related concepts
* 2 History
* 2.1 Natural occurrence
* 2.2 Pre-industrial technology
* 2.3 19th century
* 2.4 20th century
* 3 Morphology and structure
* 3.1 Variations
* 4 Nucleation and growth
* 4.1 Impact of nucleation
* 4.2 Nucleation
* 4.3 Ostwald ripening
* 4.4 Two-step mechanism – autocatalysis model
* 4.5 Measuring the rate of nucleation
* 5 Properties
* 5.1 Controlling properties
* 5.2 Large surface-area-to-volume ratio
* 5.3 Interfacial layer
* 5.4 Solvent affinity
* 5.5 Coatings
* 5.6 Diffusion across the surface
* 5.7 Ferromagnetic and ferroelectric effects
* 5.8 Mechanical properties
* 5.9 Melting point depression
* 5.10 Quantum mechanics effects
* 5.11 Regular packing
* 6 Production
* 6.1 Mechanical
* 6.2 Breakdown of biopolymers
* 6.3 Pyrolysis
* 6.4 Condensation from plasma
* 6.5 Inert gas condensation
* 6.6 Radiolysis method
* 6.7 Wet chemistry
* 6.8 Ion implantation
* 6.9 Functionalization
* 6.10 Uniformity requirements
* 7 Characterization
* 8 Health and safety
* 9 Regulation
* 10 Applications
* 10.1 Polymer reinforcement
* 10.2 Liquid properties tuner
* 10.3 Photocatalysis
* 10.4 Road paving
* 10.5 Biomedical
* 10.6 Sunscreens
* 10.7 Compounds by industrial area
* 11 See also
* 12 References
* 13 Further reading
* 14 External links

## Definitions

### International Union of Pure and Applied Chemistry (IUPAC)

In its 2012 proposed terminology for biologically related polymers, the IUPAC defined a nanoparticle as "a particle of any shape with dimensions in the 1 × 10−9 and 1 × 10−7 m range".[2]: 393 This definition evolved from one given by IUPAC in 1997.[15][16]

In the same 2012 publication, the IUPAC extends the term to include tubes and fibers with only two dimensions below 100 nm.[2]: 394

### International Organization for Standardization (ISO)

According to the International Organization for Standardization (ISO) technical specification 80004, a nanoparticle is an object with all three external dimensions in the nanoscale, whose longest and shortest axes do not differ significantly, with a significant difference typically being a factor of at least 3.[17]

### Common usage

"Nanoscale" is usually understood to be the range from 1 to 100 nm because the novel properties that differentiate particles from the bulk material typically develop at that range of sizes.

For some properties, like transparency or turbidity, ultrafiltration, stable dispersion, etc., substantial changes characteristic of nanoparticles are observed for particles as large as 500 nm. Therefore, the term is sometimes extended to that size range.[2]: 394

### Related concepts

Nanoclusters are agglomerates of nanoparticles with at least one dimension between 1 and 10 nanometers and a narrow size distribution. Nanopowders[18] are agglomerates of ultrafine particles, nanoparticles, or nanoclusters. Nanometer-sized single crystals, or single-domain ultrafine particles, are often referred to as nanocrystals.

The terms colloid and nanoparticle are not interchangeable. A colloid is a mixture which has particles of one phase dispersed or suspended within an other phase. The term applies only if the particles are larger than atomic dimensions but small enough to exhibit Brownian motion, with the critical size range (or particle diameter) typically ranging from nanometers (10−9 m) to micrometers (10−6 m).[19] Colloids can contain particles too large to be nanoparticles, and nanoparticles can exist in non-colloidal form, for examples as a powder or in a solid matrix.

## History

### Natural occurrence

Nanoparticles are naturally produced by many cosmological,[20] geological,[20][21] meteorological, and biological processes. A significant fraction (by number, if not by mass) of interplanetary dust, that is still falling on the Earth at the rate of thousands of tons per year, is in the nanoparticle range;[22][23] and the same is true of atmospheric dust particles. Many viruses have diameters in the nanoparticle range.

### Pre-industrial technology

Nanoparticles were used by artisans since prehistory, albeit without knowledge of their nature. They were used by glassmakers and potters in Classical Antiquity, as exemplified by the Roman Lycurgus cup of dichroic glass (4th century CE) and the lusterware pottery of Mesopotamia (9th century CE).[24][25][26] The latter is characterized by silver and copper nanoparticles dispersed in the glassy glaze.

### 19th century

Michael Faraday provided the first description, in scientific terms, of the optical properties of nanometer-scale metals in his classic 1857 paper. In a subsequent paper, the author (Turner) points out that: "It is well known that when thin leaves of gold or silver are mounted upon glass and heated to a temperature that is well below a red heat (~500 °C), a remarkable change of properties takes place, whereby the continuity of the metallic film is destroyed. The result is that white light is now freely transmitted, reflection is correspondingly diminished, while the electrical resistivity is enormously increased."[27][28][29]

### 20th century

During the 1970s and 80s, when the first thorough fundamental studies with nanoparticles were underway in the United States by Granqvist and Buhrman[30] and Japan within an ERATO Project,[31] researchers used the term ultrafine particles. However, during the 1990s, when the National Nanotechnology Initiative was launched in the United States, the term nanoparticle became more common, for example, see the same senior author's paper 20 years later addressing the same issue, lognormal distribution of sizes.[32]

## Morphology and structure

Nanostars of vanadium(IV) oxide (VO
2) exhibiting a crystal clusters structure resembling that of desert roses

Nanoparticles occur in a great variety of shapes, which have been given many names such as nanospheres,[33] nanorods, nanochains,[34] decahedral nanoparticles, nanostars, nanoflowers, nanoreefs,[35] nanowhiskers, nanofibers, and nanoboxes.[36]

The shapes of nanoparticles may be determined by the intrinsic crystal habit of the material, or by the influence of the environment around their creation, such as the inhibition of crystal growth on certain faces by coating additives, the shape of emulsion droplets and micelles in the precursor preparation, or the shape of pores in a surrounding solid matrix.[37] Some applications of nanoparticles require specific shapes, as well as specific sizes or size ranges.

Amorphous particles typically adopt a spherical shape (due to their microstructural isotropy).

### Variations

The breakdown of biopolymers into their nanoscale building blocks is considered a potential route to produce nanoparticles with enhanced biocompatibility and biodegradability. The most common example is the production of nanocellulose from wood pulp.[38] Other examples are nanolignin, nanochitin, or nanostarches.[39]

Hydrogel nanoparticles made of N-isopropylacrylamide hydrogel core shell can be dyed with affinity baits, internally.[40] These affinity baits allow the nanoparticles to isolate and remove undesirable proteins while enhancing the target analytes.[40]

## Nucleation and growth

### Impact of nucleation

Nucleation lays the foundation for the nanoparticle synthesis. Initial nuclei play a vital role on the size and shape of the nanoparticles that will ultimately form by acting as templating nuclei for the nanoparticle itself. Long-term stability is also determined by the initial nucleation procedures.[41] Homogeneous nucleation occurs when nuclei form uniformly throughout the parent phase and is less common. Heterogeneous nucleation, however, forms on areas such as container surfaces, impurities, and other defects.[42] Crystals can form simultaneously when nucleation occurs rapidly, resulting in a more uniform (monodisperse) product. In contrast, slow nucleation rates often lead to a diverse (polydisperse) population of crystals with varying sizes. This phenomenon is exemplified in the formation of CaCO3 crystals.[43] Controlling nucleation allows for the control of size, dispersity, and phase of nanoparticles.

The process of nucleation and growth within nanoparticles can be described by nucleation, Ostwald ripening or the two-step mechanism-autocatalysis model.[44]

### Nucleation

The original theory from 1927 of nucleation in nanoparticle formation was Classical Nucleation Theory (CNT).[45] It was believed that the changes in particle size could be described by burst nucleation alone. In 1950, Viktor LaMer used CNT as the nucleation basis for his model of nanoparticle growth. There are three portions to the LaMer model: 1. Rapid increase in the concentration of free monomers in solution, 2. fast nucleation of the monomer characterized by explosive growth of particles, 3. Growth of particles controlled by diffusion of the monomer.[46] This model describes that the growth on the nucleus is spontaneous but limited by diffusion of the precursor to the nuclei surface. The LaMer model has not been able to explain the kinetics of nucleation in any modern system.[47][48][49]

### Ostwald ripening

Ostwald ripening is a process in which large particles grow at the expense of the smaller particles as a result of dissolution of small particles and deposition of the dissolved molecules on the surfaces of the larger particles. It occurs because smaller particles have a higher surface energy than larger particles.[50] This process is typically undesirable in nanoparticle synthesis as it negatively impacts the functionality of nanoparticles.

### Two-step mechanism – autocatalysis model

In 1997, Finke and Watzky proposed a new kinetic model for the nucleation and growth of nanoparticles. This 2-step model suggested that constant slow nucleation (occurring far from supersaturation) is followed by autocatalytic growth where dispersity of nanoparticles is largely determined. This F-W (Finke-Watzky) 2-step model provides a firmer mechanistic basis for the design of nanoparticles with a focus on size, shape, and dispersity control.[44][47] The model was later expanded to a 3-step and two 4-step models between 2004 and 2008. Here, an additional step was included to account for small particle aggregation, where two smaller particles could aggregate to form a larger particle.[51] Next, a fourth step (another autocatalytic step) was added to account for a small particle agglomerating with a larger particle.[52][53][54] Finally in 2014, an alternative fourth step was considered that accounted for a atomistic surface growth on a large particle.[55]

### Measuring the rate of nucleation

As of 2014, the classical nucleation theory explained that the nucleation rate will correspond to the driving force. One method for measuring the nucleation rate is through the induction time method. This process uses the stochastic nature of nucleation and determines the rate of nucleation by analysis of the time between constant supersaturation and when crystals are first detected.[56] Another method includes the probability distribution model, analogous to the methods used to study supercooled liquids, where the probability of finding at least one nucleus at a given time is derived. As of 2019, the early stages of nucleation and the rates associated with nucleation were modelled through multiscale computational modeling. This included exploration into an improved kinetic rate equation model and density function studies using the phase-field crystal model.[57]

## Properties

The properties of a material in nanoparticle form are unusually different from those of the bulk one even when divided into micrometer-size particles.[58][59][60] Many of them arise from spatial confinement of sub-atomic particles (i.e. electrons, protons, photons) and electric fields around these particles. The large surface to volume ratio is also significant factor at this scale.[13]

### Controlling properties

The initial nucleation stages of the synthesis process heavily influence the properties of a nanoparticle. Nucleation, for example, is vital to the size of the nanoparticle. A critical radius must be met in the initial stages of solid formation, or the particles will redissolve into the liquid phase.[61] The final shape of a nanoparticle is also controlled by nucleation. Possible final morphologies created by nucleation can include spherical, cubic, needle-like, worm-like, and more particles.[44] Nucleation can be controlled predominately by time and temperature as well as the supersaturation of the liquid phase and the environment of the synthesis overall.[62]

### Large surface-area-to-volume ratio

1 kg of particles of 1 mm3 has the same surface area as 1 mg of particles of 1 nm3

Bulk materials (>100 nm in size) are expected to have constant physical properties (such as thermal and electrical conductivity, stiffness, density, and viscosity) regardless of their size, for nanoparticles, however, this is different: the volume of the surface layer (a few atomic diameters-wide) becomes a significant fraction of the particle's volume; whereas that fraction is insignificant for particles with a diameter of one micrometer or more. In other words, the surface area/volume ratio impacts certain properties of the nanoparticles more prominently than in bulk particles.[13]

### Interfacial layer

See also: Physics:Nanoparticle interfacial layer

For nanoparticles dispersed in a medium of different composition, the interfacial layer — formed by ions and molecules from the medium that are within a few atomic diameters of the surface of each particle — can mask or change its chemical and physical properties. Indeed, that layer can be considered an integral part of each nanoparticle.[6]

### Solvent affinity

### Coatings

Semiconductor nanoparticle (quantum dot) of lead sulfide with complete passivation by oleic acid, oleyl amine and hydroxyl ligands (size ~5nm)

### Diffusion across the surface

### Ferromagnetic and ferroelectric effects

The small size of nanoparticles affects their magnetic and electric properties. The ferromagnetic materials in the micrometer range is a good example: widely used in magnetic recording media, for the stability of their magnetization state, those particles smaller than 10 nm are unstable and can change their state (flip) as the result of thermal energy at ordinary temperatures, thus making them unsuitable for that application.[63]

### Mechanical properties

The reduced vacancy concentration in nanocrystals can negatively affect the motion of dislocations, since dislocation climb requires vacancy migration. In addition, there exists a very high internal pressure due to the surface stress present in small nanoparticles with high radii of curvature.[64] This causes a lattice strain that is inversely proportional to the size of the particle,[65] also well known to impede dislocation motion, in the same way as it does in the work hardening of materials.[66] For example, gold nanoparticles are significantly harder than the bulk material.[67] Furthermore, the high surface-to-volume ratio in nanoparticles makes dislocations more likely to interact with the particle surface. In particular, this affects the nature of the dislocation source and allows the dislocations to escape the particle before they can multiply, reducing the dislocation density and thus the extent of plastic deformation.[68][69]

There are unique challenges associated with the measurement of mechanical properties on the nanoscale, as conventional means such as the universal testing machine cannot be employed. As a result, new techniques such as nanoindentation have been developed that complement existing electron microscope and scanning probe methods.[70] Atomic force microscopy (AFM) can be used to perform nanoindentation to measure hardness, elastic modulus, and adhesion between nanoparticle and substrate.[71] The particle deformation can be measured by the deflection of the cantilever tip over the sample. The resulting force-displacement curves can be used to calculate elastic modulus.[72] However, it is unclear whether particle size and indentation depth affect the measured elastic modulus of nanoparticles by AFM.[72]

Adhesion and friction forces are important considerations in nanofabrication, lubrication, device design, colloidal stabilization, and drug delivery.[71] The capillary force is the main contributor to the adhesive force under ambient conditions.[73] The adhesion and friction force can be obtained from the cantilever deflection if the AFM tip is regarded as a nanoparticle. However, this method is limited by tip material and geometric shape.[74] The colloidal probe technique overcomes these issues by attaching a nanoparticle to the AFM tip, allowing control oversize, shape, and material.[75] While the colloidal probe technique is an effective method for measuring adhesion force, it remains difficult to attach a single nanoparticle smaller than 1 micron onto the AFM force sensor.[75]

Another technique is in situ TEM, which provides real-time, high resolution imaging of nanostructure response to a stimulus. For example, an in situ force probe holder in TEM was used to compress twinned nanoparticles and characterize yield strength.[76] In general, the measurement of the mechanical properties of nanoparticles is influenced by many factors including uniform dispersion of nanoparticles, precise application of load, minimum particle deformation, calibration, and calculation model.[71]

Like bulk materials, the properties of nanoparticles are materials dependent. For spherical polymer nanoparticles, glass transition temperature and crystallinity may affect deformation and change the elastic modulus when compared to the bulk material.[71] However, size-dependent behavior of elastic moduli could not be generalized across polymers.[71] As for crystalline metal nanoparticles, dislocations were found to influence the mechanical properties of nanoparticles, contradicting the conventional view that dislocations are absent in crystalline nanoparticles.[71]

### Melting point depression

A material may have lower melting point in nanoparticle form than in the bulk form. For example, 2.5 nm gold nanoparticles melt at about 300 °C, whereas bulk gold melts at 1064 °C.[77]

### Quantum mechanics effects

Quantum effects are responsible for the deep-red to black color of gold or silicon nanopowders and nanoparticle suspensions.[77] Absorption of solar radiation is much higher in materials composed of nanoparticles than in thin films of continuous sheets of material. In both solar PV and solar thermal applications, by controlling the size, shape, and material of the particles, it is possible to control solar absorption.[78][79][80][81]

Core-shell nanoparticles can support simultaneously both electric and magnetic resonances, demonstrating entirely new properties when compared with bare metallic nanoparticles if the resonances are properly engineered.[82][83][84] The formation of the core-shell structure from two different metals enables an energy exchange between the core and the shell, typically found in upconverting nanoparticles and downconverting nanoparticles, and causes a shift in the emission wavelength spectrum.[85]

By introducing a dielectric layer, plasmonic core (metal)-shell (dielectric) nanoparticles enhance light absorption by increasing scattering. Recently, the metal core-dielectric shell nanoparticle has demonstrated a zero backward scattering with enhanced forward scattering on a silicon substrate when surface plasmon is located in front of a solar cell.[86]

### Regular packing

Nanoparticles of sufficiently uniform size may spontaneously settle into regular arrangements, forming a colloidal crystal. These arrangements may exhibit original physical properties, such as observed in photonic crystals.[87][88]

## Production

Artificial nanoparticles can be created from any solid or liquid material, including metals, dielectrics, and semiconductors. They may be internally homogeneous or heterogenous, e.g. with a core–shell structure.[82][83][84][89]

There are several methods for creating nanoparticles, including gas condensation, attrition, chemical precipitation,[90] ion implantation, pyrolysis, hydrothermal synthesis, and biosynthesis.[91]

### Mechanical

Friable macro- or micro-scale solid particles can be ground in a ball mill, a planetary ball mill, or other size-reducing mechanism until enough of them are in the nanoscale size range. The resulting powder can be air classified to extract the nanoparticles.[92][93][94]

### Breakdown of biopolymers

### Pyrolysis

### Condensation from plasma

Nanoparticles of pure metals, oxides, carbides, and nitrides,[95] can be created by vaporizing a solid precursor with a thermal plasma and then condensing the vapor by expansion or quenching in a suitable gas or liquid. The plasma can be produced by dc jet, electric arc, or radio frequency (RF) induction. The thermal plasma can reach temperatures of 10.000 K and can thus also synthesize nanopowders with very high boiling points. Metal wires can be vaporized by the exploding wire method.

### Inert gas condensation

Inert-gas condensation is frequently used to produce metallic nanoparticles. The metal is evaporated in a vacuum chamber containing a reduced atmosphere of an inert gas.[96] Condensation of the supersaturated metal vapor results in creation of nanometer-size particles, which can be entrained in the inert gas stream and deposited on a substrate or studied in situ. Early studies were based on thermal evaporation.[96] Using magnetron sputtering to create the metal vapor allows to achieve higher yields.[97] The method can easily be generalized to alloy nanoparticles by choosing appropriate metallic targets. The use of sequential growth schemes, where the particles travel through a second metallic vapor, results in growth of core-shell (CS) structures.[98][99][100][89]

### Radiolysis method

a) Transmission electron microscopy (TEM) image of Hf nanoparticles grown by magnetron-sputtering inert-gas condensation (inset: size distribution)[101] and b) energy dispersive X-ray (EDX) mapping of Ni and Ni@Cu core@shell nanoparticles.[99]

Nanoparticles can also be formed using radiation chemistry. Radiolysis from gamma rays can create strongly active free radicals in solution. This relatively simple technique uses a minimum number of chemicals. These including water, a soluble metallic salt, a radical scavenger (often a secondary alcohol), and a surfactant (organic capping agent). High gamma doses on the order of 104 gray are required. In this process, reducing radicals will drop metallic ions down to the zero-valence state. A scavenger chemical will preferentially interact with oxidizing radicals to prevent the re-oxidation of the metal. Once in the zero-valence state, metal atoms begin to coalesce into particles. A chemical surfactant surrounds the particle during formation and regulates its growth. In sufficient concentrations, the surfactant molecules stay attached to the particle. This prevents it from dissociating or forming clusters with other particles. Formation of nanoparticles using the radiolysis method allows for tailoring of particle size and shape by adjusting precursor concentrations and gamma dose.[102]

### Wet chemistry

Nanoparticles of certain materials can be created by "wet" chemical processes, in which solutions of suitable compounds are mixed or otherwise treated to form an insoluble precipitate of the desired material. The size of the particles of the latter is adjusted by choosing the concentration of the reagents and the temperature of the solutions, and through the addition of suitable inert agents that affect the viscosity and diffusion rate of the liquid. With different parameters, the same general process may yield other nanoscale structures of the same material, such as aerogels and other porous networks.[103]

Electroless deposition provides a unique opportunity for growing nanoparticles onto surface without the need for costly spin coating, electrodeposition, or physical vapor deposition. Electroless deposition processes can form colloid suspensions catalytic metal or metal oxide deposition. The suspension of nanoparticles that result from this process is an example of colloid. Typical instances of this method are the production of metal oxide or hydroxide nanoparticles by hydrolysis of metal alkoxides and chlorides.[104][4]

Besides being cheap and convenient, the wet chemical approach allows fine control of the particle's chemical composition. Even small quantities of dopants, such as organic dyes and rare earth metals, can be introduced in the reagent solutions end up uniformly dispersed in the final product.[105][106]

### Ion implantation

### Functionalization

For example, suspensions of graphene particles can be stabilized by functionalization with gallic acid groups.[107]

For biological applications, the surface coating should be polar to give high aqueous solubility and prevent nanoparticle aggregation. In serum or on the cell surface, highly charged coatings promote non-specific binding, whereas polyethylene glycol linked to terminal hydroxyl or methoxy groups repel non-specific interactions.[108][109] By the immobilization of thiol groups on the surface of nanoparticles or by coating them with thiomers high (muco)adhesive and cellular uptake enhancing properties can be introduced.[110]

Nanoparticles can be linked to biological molecules that can act as address tags, directing them to specific sites within the body[111] specific organelles within the cell,[112] or causing them to follow specifically the movement of individual protein or RNA molecules in living cells.[113] Common address tags are monoclonal antibodies, aptamers, streptavidin, or peptides. These targeting agents should ideally be covalently linked to the nanoparticle and should be present in a controlled number per nanoparticle. Multivalent nanoparticles, bearing multiple targeting groups, can cluster receptors, which can activate cellular signaling pathways, and give stronger anchoring. Monovalent nanoparticles, bearing a single binding site,[114][115][116] avoid clustering and so are preferable for tracking the behavior of individual proteins.

It has been shown that catalytic activity and sintering rates of a functionalized nanoparticle catalyst is correlated to nanoparticles' number density[117]

Coatings that mimic those of red blood cells can help nanoparticles evade the immune system.[118]

### Uniformity requirements

Uncontrolled agglomeration of powders due to attractive van der Waals forces can also give rise to microstructural heterogeneity. Differential stresses that develop as a result of non-uniform drying shrinkage are directly related to the rate at which the solvent can be removed, and thus highly dependent upon the distribution of porosity. Such stresses have been associated with a plastic-to-brittle transition in consolidated bodies, and can yield to crack propagation in the unfired body if not relieved.[119][120][121]

In addition, any fluctuations in packing density in the compact as it is prepared for the kiln are often amplified during the sintering process, yielding inhomogeneous densification. Some pores and other structural defects associated with density variations have been shown to play a detrimental role in the sintering process by growing and thus limiting end-point densities. Differential stresses arising from inhomogeneous densification have also been shown to result in the propagation of internal cracks, thus becoming the strength-controlling flaws.[122][123][124]

Inert gas evaporation and inert gas deposition[30][31] are free many of these defects due to the distillation (cf. purification) nature of the process and having enough time to form single crystal particles, however even their non-aggreated deposits have lognormal size distribution, which is typical with nanoparticles.[31] The reason why modern gas evaporation techniques can produce a relatively narrow size distribution is that aggregation can be avoided.[31] However, even in this case, random residence times in the growth zone, due to the combination of drift and diffusion, result in a size distribution appearing lognormal.[32]

It would, therefore, appear desirable to process a material in such a way that it is physically uniform with regard to the distribution of components and porosity, rather than using particle size distributions that will maximize the green density. The containment of a uniformly dispersed assembly of strongly interacting particles in suspension requires total control over interparticle forces. Monodisperse nanoparticles and colloids provide this potential.[125]

## Characterization

Main article: Chemistry:Characterization of nanoparticles

Nanoparticles have different analytical requirements than conventional chemicals, for which chemical composition and concentration are sufficient metrics. Nanoparticles have other physical properties that must be measured for a complete description, such as size, shape, surface properties, crystallinity, and dispersion state. Additionally, sampling and laboratory procedures can perturb their dispersion state or bias the distribution of other properties.[126][127] In environmental contexts, an additional challenge is that many methods cannot detect low concentrations of nanoparticles that may still have an adverse effect.[126] For some applications, nanoparticles may be characterized in complex matrices such as water, soil, food, polymers, inks, complex mixtures of organic liquids such as in cosmetics, or blood.[128][129]

There are several overall categories of methods used to characterize nanoparticles. Microscopy methods generate images of individual nanoparticles to characterize their shape, size, and location. Electron microscopy and scanning probe microscopy are the dominant methods. Because nanoparticles have a size below the diffraction limit of visible light, conventional optical microscopy is not useful. Electron microscopes can be coupled to spectroscopic methods that can perform elemental analysis. Microscopy methods are destructive and can be prone to undesirable artifacts from sample preparation, or from probe tip geometry in the case of scanning probe microscopy. Additionally, microscopy is based on single-particle measurements, meaning that large numbers of individual particles must be characterized to estimate their bulk properties.[126][128]

Spectroscopy, which measures the particles' interaction with electromagnetic radiation as a function of wavelength, is useful for some classes of nanoparticles to characterize concentration, size, and shape. X-ray, ultraviolet–visible, infrared, and nuclear magnetic resonance spectroscopy can be used with nanoparticles.[130][126][128] Light-scattering methods using laser light, X-rays, or neutron scattering are used to determine particle size, with each method suitable for different size ranges and particle compositions.[126][128] Some miscellaneous methods are electrophoresis for surface charge, the Brunauer–Emmett–Teller method for surface area, and X-ray diffraction for crystal structure,[126] as well as mass spectrometry for particle mass, and particle counters for particle number.[128] Chromatography, centrifugation, and filtration techniques can be used to separate nanoparticles by size or other physical properties before or during characterization.[126]

## Health and safety

See also: Physics:Health and safety hazards of nanomaterials, Particulates, and Nanotoxicology

Nanoparticles present possible dangers, both medically and environmentally.[131][132][133][134] Most of these are due to the high surface to volume ratio, which can make the particles very reactive or catalytic.[135] They are also thought to aggregate on phospholipid bilayers[136] and pass through cell membranes in organisms, and their interactions with biological systems are relatively unknown.[137][138] However, it is unlikely the particles would enter the cell nucleus, Golgi complex, endoplasmic reticulum or other internal cellular components due to the particle size and intercellular agglomeration.[139] A recent study looking at the effects of ZnO nanoparticles on human immune cells has found varying levels of susceptibility to cytotoxicity.[140] There are concerns that pharmaceutical companies, seeking regulatory approval for nano-reformulations of existing medicines, are relying on safety data produced during clinical studies of the earlier, pre-reformulation version of the medicine. This could result in regulatory bodies, such as the FDA, missing new side effects that are specific to the nano-reformulation.[141] However considerable research has demonstrated that zinc nanoparticles are not absorbed into the bloodstream in vivo.[142]

Concern has also been raised over the health effects of respirable nanoparticles from certain combustion processes.[143][144] Preclinical investigations have demonstrated that some inhaled or injected noble metal nano-architectures avoid persistence in organisms.[145][146] As of 2013 the U.S. Environmental Protection Agency was investigating the safety of the following nanoparticles:[147]

* Carbon nanotubes: Carbon materials have a wide range of uses, ranging from composites for use in vehicles and sports equipment to integrated circuits for electronic components. The interactions between nanomaterials such as carbon nanotubes and natural organic matter strongly influence both their aggregation and deposition, which strongly affects their transport, transformation, and exposure in aquatic environments. In past research, carbon nanotubes exhibited some toxicological impacts that will be evaluated in various environmental settings in current EPA chemical safety research. EPA research will provide data, models, test methods, and best practices to discover the acute health effects of carbon nanotubes and identify methods to predict them.[147]
* Cerium oxide: Nanoscale cerium oxide is used in electronics, biomedical supplies, energy, and fuel additives. Many applications of engineered cerium oxide nanoparticles naturally disperse themselves into the environment, which increases the risk of exposure. There is ongoing exposure to new diesel emissions using fuel additives containing CeO2 nanoparticles, and the environmental and public health impacts of this new technology are unknown. EPA's chemical safety research is assessing the environmental, ecological, and health implications of nanotechnology-enabled diesel fuel additives.[147]
* Titanium dioxide: Nano titanium dioxide is currently used in many products. Depending on the type of particle, it may be found in sunscreens, cosmetics, and paints and coatings. It is also being investigated for use in removing contaminants from drinking water.[147]
* Nano Silver: Nano Silver is being incorporated into textiles, clothing, food packaging, and other materials to eliminate bacteria. EPA and the U.S. Consumer Product Safety Commission are studying certain products to see whether they transfer nano-size silver particles in real-world scenarios. EPA is researching this topic to better understand how much nano-silver children come in contact with in their environments.[147]
* Iron: While nano-scale iron is being investigated for many uses, including "smart fluids" for uses such as optics polishing and as a better-absorbed iron nutrient supplement, one of its more prominent current uses is to remove contamination from groundwater. This use, supported by EPA research, is being piloted at a number of sites across the United States.[147]

## Regulation

As of 2016, the U.S. Environmental Protection Agency had conditionally registered, for a period of four years, only two nanomaterial pesticides as ingredients. The EPA differentiates nanoscale ingredients from non-nanoscale forms of the ingredient, but there is little scientific data about potential variation in toxicity. Testing protocols still need to be developed.[148]

## Applications

As the most prevalent morphology of nanomaterials used in consumer products, nanoparticles have an enormous range of potential and actual applications. Table below summarizes the most common nanoparticles used in various product types available on the global markets.

Scientific research on nanoparticles is intense as they have many potential applications in pre-clinical[149][150] and clinical medicine, physics,[151][152][153] optics,[154][155][156] and electronics.[83][79][157][80] The U.S. National Nanotechnology Initiative offers government funding focused on nanoparticle research. The use of nanoparticles in laser dye-doped poly(methyl methacrylate) (PMMA) laser gain media was demonstrated in 2003 and it has been shown to improve conversion efficiencies and to decrease laser beam divergence.[158] Researchers attribute the reduction in beam divergence to improved dn/dT characteristics of the organic-inorganic dye-doped nanocomposite. The optimum composition reported by these researchers is 30% w/w of SiO2 (~ 12 nm) in dye-doped PMMA. Nanoparticles are being investigated as a potential drug delivery system.[159] Drugs, growth factors or other biomolecules can be conjugated to nano particles to aid targeted delivery.[160] This nanoparticle-assisted delivery allows for spatial and temporal controls of the loaded drugs to achieve the most desirable biological outcome. Nanoparticles are also studied for possible applications as dietary supplements for delivery of biologically active substances, for example mineral elements.[161]

### Polymer reinforcement

Clay nanoparticles, when incorporated into polymer matrices, increase reinforcement, leading to stronger plastics, verifiable by a higher glass transition temperature and other mechanical property tests. These nanoparticles are hard, and impart their properties to the polymer (plastic). Nanoparticles have also been attached to textile fibers in order to create smart and functional clothing.[162]

### Liquid properties tuner

The inclusion of nanoparticles in a solid or liquid medium can substantially change its mechanical properties, such as elasticity, plasticity, viscosity, compressibility.[163][164]

### Photocatalysis

Being smaller than the wavelengths of visible light, nanoparticles can be dispersed in transparent media without affecting its transparency at those wavelengths. This property is exploited in many applications, such as photocatalysis.

### Road paving

Asphalt modification through nanoparticles can be considered as an interesting low-cost technique in asphalt pavement engineering providing novel perspectives in making asphalt materials more durable.[165]

### Biomedical

Nanoscale particles are used in biomedical applications as drug carriers or imaging contrast agents in microscopy. Anisotropic nanoparticles are a good candidate in biomolecular detection.[13] Moreover, nanoparticles for nucleic acid delivery offer an unprecedented opportunity to overcome some drawbacks related to the delivery, owing to their tunability with diverse physico-chemical properties, they can readily be functionalized with any type of biomolecules/moieties for selective targeting.[166]

Using nanoparticles in cancer treatment is being extensively researched. Certain characteristics of the tumor microenvironment, including leaky vasculature and poor lymphatic drainage, lead to the accumulation of NPs in the tumor.[167] This is known as the enhanced permeability and retention (EPR) effect, and is a type of passive targeting. Additionally, ligands that bind to certain expressed or over-expressed receptors in the tumor microenvironment can be conjugated to the surface of nanoparticles to actively target the tumor.[168] The accumulation of nanoparticles in the tumor can reduce adverse side effects, which is a major drawback of chemotherapy.{{citation needed|date=July 2025} In drug delivery, the acidic pH of the tumor microenvironment is often exploited to increase the release of the drug from pH-sensitive materials.[169] Additionally, some NPs can generate heat under laser irradiation (photothermal therapy) or alternating magnetic field (magnetic hyperthermia), which can both kill cancer cells, and release drugs loaded in the nanoparticle.[170]

Some high-Z metal NPs are currently being investigated as radiosensitizers to enhance the effects of radiation therapy in cancer treatment.[171]

### Sunscreens

Titanium dioxide nanoparticles imparts what is known as the self-cleaning effect, which lend useful water-repellant and antibacterial properties to paints and other products. Zinc oxide nanoparticles have been found to have superior UV blocking properties and are widely used in the preparation of sunscreen lotions,[172] being completely photostable[173] though toxic.[174][175][176][177][178][179]

### Compounds by industrial area

No.  | Industrial sectors  | Nanoparticles

|
|

1  | agriculture  |

* silver
* silicon dioxide
* potassium
* calcium
* iron
* zinc
* phosphorus
* boron
* zinc oxide
* molybdenum

2  | automotive  |

* tungsten disulfide
* silicon dioxide
* clay
* titanium dioxide
* diamond
* copper
* cobalt oxide
* zinc oxide
* boron nitride
* zirconium dioxide
* tungsten
* γ-aluminium oxide
* boron
* palladium
* platinum
* cerium(IV) oxide
* carnauba
* aluminium oxide
* silver
* calcium carbonate
* calcium sulfonate

3  | construction  |

* titanium dioxide
* silicon dioxide
* silver
* clay
* aluminium oxide
* calcium carbonate
* calcium silicate hydrate
* carbon
* aluminium phosphate
* cerium(IV) oxide
* calcium hydroxide

4  | cosmetics  |

* silver
* titanium dioxide
* gold
* carbon
* zinc oxide
* silicon dioxide
* clay
* sodium silicate
* kojic acid
* hydroxycarboxylic acid

5  | electronics  |

* silver
* aluminum
* silicon dioxide
* palladium

6  | environment  |

* silver
* titanium dioxide
* carbon
* manganese oxide
* clay
* gold
* selenium

7  | food  |

* silver
* clay
* titanium dioxide
* gold
* zinc oxide
* silicon dioxide
* calcium
* copper
* zinc
* platinum
* manganese
* palladium
* carbon

8  | home appliance  |

* silver
* zinc oxide
* silicon dioxide
* diamond
* titanium dioxide

9  | medicine[180] |

* silver
* gold
* hydroxyapatite
* clay
* titanium dioxide
* silicon dioxide
* zirconium dioxide
* carbon
* diamond
* aluminium oxide
* ytterbium trifluoride

10  | petroleum  |

* tungsten disulfide
* zinc oxide
* silicon dioxide
* diamond
* clay
* boron
* boron nitride
* silver
* titanium dioxide
* tungsten
* γ-aluminium oxide
* carbon
* molybdenum disulfide

11  | printing  | toner, deposited by a printer onto paper or other substrate
12  | renewable energies  |

* titanium
* palladium
* tungsten disulfide
* silicon dioxide
* clay
* graphite
* zirconium(IV) oxide-yttria stabilized
* carbon
* gd-doped-cerium(IV) oxide
* nickel cobalt oxide
* nickel(II) oxide
* rhodium
* sm-doped-cerium(IV) oxide
* barium strontium titanate
* silver

13  | sports and fitness  |

* silver
* titanium dioxide
* gold
* clay
* carbon

14  | textile  |

* silver
* carbon
* titanium dioxide
* copper sulfide
* clay
* gold
* polyethylene terephthalate
* silicon dioxide

## See also

* Carbon quantum dot
* Ceramic engineering
* Coating
* Colloid
* Colloidal crystal
* Colloidal gold
* Colloid-facilitated transport
* Eigencolloid
* Fiveling or decahedral nanoparticle
* Fullerene
* Gallium(II) selenide
* Icosahedral twins
* Indium(III) selenide
* Liposome
* Magnetic immunoassay
* Magnetoelastic filament a.k.a. magnetic nanochain
* Magnetic nanoparticles
* Nanobiotechnology
* Nanocrystalline silicon
* Nanofluid
* Nanogeoscience
* Nanomaterials
* Nanomedicine
* Nanoparticle deposition
* Nanoparticle tracking analysis
* Nanotechnology
* Patchy particles
* Photonic crystal
* Plasmon
* Platinum nanoparticle
* Quantum dot
* Self-assembly of nanoparticles
* Silicon quantum dot
* Silicon
* Silver Nano
* Sol–gel process
* Synthesis of nanoparticles by fungi
* Transparent material
* Upconverting nanoparticles
* Erythrocyte membrane-coated nanoparticles

## References

1. ↑ U.S. Environmental Protection Agency (): "Module 3: Characteristics of Particles Particle Size Categories". From the EPA Website.
2. ↑ 2.0 2.1 2.2 2.3 2.4 Vert, M.; Doi, Y.; Hellwich, K. H.; Hess, M.; Hodge, P.; Kubisa, P.; Rinaudo, M.; Schué, F. O. (2012). "Terminology for biorelated polymers and applications (IUPAC Recommendations 2012)". Pure and Applied Chemistry 84 (2): 377–410. doi:10.1351/PAC-REC-10-12-04.
3. ↑ Torres-Torres, C; López-Suárez, A; Can-Uc, B; Rangel-Rojo, R; Tamayo-Rivera, L; Oliver, A (2015-07-24). "Collective optical Kerr effect exhibited by an integrated configuration of silicon quantum dots and gold nanoparticles embedded in ion-implanted silica". Nanotechnology 26 (29). doi:10.1088/0957-4484/26/29/295701. ISSN 0957-4484. PMID 26135968. Bibcode: 2015Nanot..26C5701T. https://iopscience.iop.org/article/10.1088/0957-4484/26/29/295701.
4. ↑ 4.0 4.1 Chae, Seung Yong; Park, Myun Kyu; Lee, Sang Kyung; Kim, Taek Young; Kim, Sang Kyu; Lee, Wan In (August 2003). "Preparation of Size-Controlled TiO 2 Nanoparticles and Derivation of Optically Transparent Photocatalytic Films". Chemistry of Materials 15 (17): 3326–3331. doi:10.1021/cm030171d. Bibcode: 2003ChMat..15.3326C.
5. ↑ Jacques Simonis, Jean; Koetzee Basson, Albertus (2011). "Evaluation of a low-cost ceramic micro-porous filter for elimination of common disease microorganisms". Physics and Chemistry of the Earth, Parts A/B/C 36 (14–15): 1129–1134. doi:10.1016/j.pce.2011.07.064. Bibcode: 2011PCE....36.1129S.
6. ↑ 6.0 6.1 Silvera Batista, C. A.; Larson, R. G.; Kotov, N. A. (9 October 2015). "Nonadditivity of nanoparticle interactions". Science 350 (6257). doi:10.1126/science.1242477. PMID 26450215.
7. ↑ Cai, Wei; Nix, William D. (September 2016) (in en). Imperfections in Crystalline Solids. Cambridge Core. doi:10.1017/cbo9781316389508. ISBN 978-1-107-12313-7. https://www.cambridge.org/core/books/imperfections-in-crystalline-solids/3A193C8DEF36073F9E2EF07EEA6A5D96. Retrieved 2020-05-21.
8. ↑ Chen, Chien-Chun; Zhu, Chun; White, Edward R.; Chiu, Chin-Yi; Scott, M. C.; Regan, B. C.; Marks, Laurence D.; Huang, Yu et al. (April 2013). "Three-dimensional imaging of dislocations in a nanoparticle at atomic resolution". Nature 496 (7443): 74–77. doi:10.1038/nature12009. PMID 23535594. Bibcode: 2013Natur.496...74C.
9. ↑ Guo, Dan; Xie, Guoxin; Luo, Jianbin (8 January 2014). "Mechanical properties of nanoparticles: basics and applications". Journal of Physics D: Applied Physics 47 (1). doi:10.1088/0022-3727/47/1/013001. Bibcode: 2014JPhD...47a3001G.
10. ↑ Khan, Ibrahim; Saeed, Khalid; Khan, Idrees (November 2019). "Nanoparticles: Properties, applications and toxicities". Arabian Journal of Chemistry 12 (7): 908–931. doi:10.1016/j.arabjc.2017.05.011. Bibcode: 2019ArJC...12..908K.
11. ↑ Carlton, C.E.; Rabenberg, L.; Ferreira, P.J. (September 2008). "On the nucleation of partial dislocations in nanoparticles". Philosophical Magazine Letters 88 (9–10): 715–724. doi:10.1080/09500830802307641. Bibcode: 2008PMagL..88..715C.
12. ↑ "Anisotropic Nanostructures" (in en-US). https://mirkin-group.northwestern.edu/project/anisotropic-nanostructures/.
13. ↑ 13.0 13.1 13.2 13.3 Sajanlal, Panikkanvalappil R.; Sreeprasad, Theruvakkattil S.; Samal, Akshaya K.; Pradeep, Thalappil (2011-02-16). "Anisotropic nanomaterials: structure, growth, assembly, and functions". Nano Reviews 2: 5883. doi:10.3402/nano.v2i0.5883. ISSN 2000-5121. PMID 22110867.
14. ↑ 14.0 14.1 Knauer, Andrea; Koehler, J. Michael (2016). "Explanation of the size dependent in-plane optical resonance of triangular silver nanoprisms". Physical Chemistry Chemical Physics 18 (23): 15943–15949. doi:10.1039/c6cp00953k. PMID 27241479. Bibcode: 2016PCCP...1815943K.
15. ↑ MacNaught, Alan D., ed (1997). Compendium of Chemical Terminology: IUPAC Recommendations (2nd ed.). Blackwell Science. ISBN 978-0-86542-684-9.
16. ↑ Alemán, J. V.; Chadwick, A. V.; He, J.; Hess, M.; Horie, K.; Jones, R. G.; Kratochvíl, P.; Meisel, I. et al. (1 January 2007). "Definitions of terms relating to the structure and processing of sols, gels, networks, and inorganic-organic hybrid materials (IUPAC Recommendations 2007)". Pure and Applied Chemistry 79 (10): 1801–1829. doi:10.1351/pac200779101801. Bibcode: 2007PApCh..79.1801A.
17. ↑ "ISO/TS 80004-2: Nanotechnologies Vocabulary Part 2: Nano-objects". 2015. https://www.iso.org/obp/ui/#iso:std:iso:ts:80004:-2:ed-1:v1:en.
18. ↑ Fahlman, B. D. (2007). Materials Chemistry. Springer. pp. 282 283. ISBN 978-1-4020-6119-6. https://books.google.com/books?id=lByCslty2oUC&pg=PT287.
19. ↑ Pais, A. (2005). Subtle is the Lord: The Science and the Life of Albert Einstein. Oxford University Press. ISBN 978-0-19-280672-7. https://books.google.com/books?id=U2mO4nUunuwC. Retrieved 6 December 2016.
20. ↑ 20.0 20.1 Simakov, S. K. (2018). "Nano- and micron-sized diamond genesis in nature: An overview". Geoscience Frontiers 9 (6): 1849–1858. doi:10.1016/j.gsf.2017.10.006. Bibcode: 2018GeoFr...9.1849S.
21. ↑ Simakov, S. K.; Kouchi, A.; Scribano, V.; Kimura, Y.; Hama, T.; Suzuki, N.; Saito, H.; Yoshizawa, T. (2015). "Nanodiamond Finding in the Hyblean Shallow Mantle Xenoliths". Scientific Reports 5. doi:10.1038/srep10765. PMID 26030133. Bibcode: 2015NatSR...510765S.
22. ↑ Plane, John M. C. (2012). "Cosmic dust in the earth's atmosphere". Chemical Society Reviews 41 (19): 6507–6518. doi:10.1039/C2CS35132C. PMID 22678029. Bibcode: 2012ChSRv..41.6507P.
23. ↑ Zook, Herbert A. (2001). "Spacecraft Measurements of the Cosmic Dust Flux". in Peucker-Ehrenbrink, B.; Schmitz, B.. Accretion of Extraterrestrial Matter Throughout Earth's History. Boston, MA: Springer. pp. 75–92. doi:10.1007/978-1-4419-8694-8_5. ISBN 978-1-4613-4668-5.
24. ↑ "Nanotechnology Timeline | Nano". https://www.nano.gov/timeline.
25. ↑ Reiss, Gunter; Hutten, Andreas (2010). "Magnetic Nanoparticles". in Sattler, Klaus D.. Handbook of Nanophysics: Nanoparticles and Quantum Dots. CRC Press. pp. 2 1. ISBN 978-1-4200-7545-8. https://books.google.com/books?id=DiFMPmXSsLUC&pg=SA2-PA1.
26. ↑ Khan, Firdos Alam (2012). Biotechnology Fundamentals. CRC Press. p. 328. ISBN 978-1-4398-2009-4. https://books.google.com/books?id=-s5oRDUuMSIC&pg=PA328.
27. ↑ Faraday, Michael (1857). "Experimental relations of gold (and other metals) to light". Phil. Trans. R. Soc. Lond. 147: 145 181. doi:10.1098/rstl.1857.0011. Bibcode: 1857RSPT..147..145F.
28. ↑ Beilby, George Thomas (31 January 1904). "The effect of heat and of solvents on thin films of metal". Proceedings of the Royal Society of London 72 (477–486): 226–235. doi:10.1098/rspl.1903.0046. Bibcode: 1903RSPS...72..226B.
29. ↑ Turner, T. (1908). "Transparent Silver and Other Metallic Films". Proceedings of the Royal Society A 81 (548): 301–310. doi:10.1098/rspa.1908.0084. Bibcode: 1908RSPSA..81..301T.
30. ↑ 30.0 30.1 Granqvist, C.; Buhrman, R.; Wyns, J.; Sievers, A. (1976). "Far-Infrared Absorption in Ultrafine Al Particles". Physical Review Letters 37 (10): 625 629. doi:10.1103/PhysRevLett.37.625. Bibcode: 1976PhRvL..37..625G.
31. ↑ 31.0 31.1 31.2 31.3 Hayashi, C.; Uyeda, R; Tasaki, A. (1997). Ultra-fine particles: exploratory science and technology (1997 Translation of the Japan report of the related ERATO Project 1981 86). Noyes Publications.
32. ↑ 32.0 32.1 Kiss, L B; Söderlund, J; Niklasson, G A; Granqvist, C G (1 March 1999). "New approach to the origin of lognormal size distributions of nanoparticles". Nanotechnology 10 (1): 25–28. doi:10.1088/0957-4484/10/1/006. Bibcode: 1999Nanot..10...25K.
33. ↑ Agam, M. A.; Guo, Q (2007). "Electron Beam Modification of Polymer Nanospheres". Journal of Nanoscience and Nanotechnology 7 (10): 3615–9. doi:10.1166/jnn.2007.814. PMID 18330181. https://research.birmingham.ac.uk/en/publications/9de3c02e-e57c-44ae-aabe-50ea2d491d0b.
34. ↑ Kralj, Slavko; Makovec, Darko (27 October 2015). "Magnetic Assembly of Superparamagnetic Iron Oxide Nanoparticle Clusters into Nanochains and Nanobundles". ACS Nano 9 (10): 9700–7. doi:10.1021/acsnano.5b02328. PMID 26394039. Bibcode: 2015ACSNa...9.9700K.
35. ↑ Choy J.H.; Jang E.S.; Won J.H.; Chung J.H.; Jang D.J.; Kim Y.W. (2004). "Hydrothermal route to ZnO nanocoral reefs and nanofibers". Appl. Phys. Lett. 84 (2): 287. doi:10.1063/1.1639514. Bibcode: 2004ApPhL..84..287C.
36. ↑ Sun, Y; Xia, Y (2002). "Shape-controlled synthesis of gold and silver nanoparticles". Science 298 (5601): 2176–9. doi:10.1126/science.1077229. PMID 12481134. Bibcode: 2002Sci...298.2176S. https://semanticscholar.org/paper/10be141980be0fe3606f5347ee9721ad43392eb4.
37. ↑ Murphy, C. J. (13 December 2002). "MATERIALS SCIENCE: Nanocubes and Nanoboxes". Science 298 (5601): 2139–2141. doi:10.1126/science.1080007. PMID 12481122.
38. ↑ Dufresne, Alain (June 2013). "Nanocellulose: a new ageless bionanomaterial". Materials Today 16 (6): 220–227. doi:10.1016/j.mattod.2013.06.004.
39. ↑ Le Corre, Déborah; Bras, Julien; Dufresne, Alain (10 May 2010). "Starch Nanoparticles: A Review". Biomacromolecules 11 (5): 1139–1153. doi:10.1021/bm901428y. PMID 20405913. Bibcode: 2010Biomm..11.1139L.
40. ↑ 40.0 40.1 Luchini, Alessandra; Geho, David H.; Bishop, Barney; Tran, Duy; Xia, Cassandra; Dufour, Robert L.; Jones, Clinton D.; Espina, Virginia et al. (January 2008). "Smart Hydrogel Particles: Biomarker Harvesting: One-Step Affinity Purification, Size Exclusion, and Protection against Degradation". Nano Letters 8 (1): 350–361. doi:10.1021/nl072174l. PMID 18076201. Bibcode: 2008NanoL...8..350L.
41. ↑ Gommes, Cedric J. (2019). "Ostwald ripening of confined nanoparticles: Chemomechanical coupling in nanopores". Nanoscale 11 (15): 7386–7393. doi:10.1039/C9NR01349K. PMID 30938749.
42. ↑ Thanh, N. T.; MacLean, N.; Mahiddine, S. (2014). "Mechanisms of nucleation and growth of nanoparticles in solution". Chem. Rev. 114 (15): 7610–7630. doi:10.1021/cr400544s. PMID 25003956. https://discovery.ucl.ac.uk/id/eprint/1448058/.
43. ↑ Seepma, Sergěj Y.M.H.; Ruiz-Hernandez, Sergio E.; Nehrke, Gernot; Soetaert, Karline; Philipse, Albert P.; Kuipers, Bonny W. M.; Wolthers, Mariëtte (2021). "Controlling CaCO3 particle size with {Ca2+}:{CO32–} ratios in aqueous environments". Crystal Growth & Design 21 (3): 1576–1590. doi:10.1021/acs.cgd.0c01403. ISSN 1528-7505. PMID 33762898.
44. ↑ 44.0 44.1 44.2 Kulkarni, Samir A.; Kadam, Somnath S.; Meekes, Hugo; Stankiewicz, Andrzej I.; Ter Horst, Joop H. (2013). "Crystal Nucleation Kinetics from Induction Times and Metastable Zone Widths". Crystal Growth & Design 13 (6): 2435–2440. doi:10.1021/cg400139t. Bibcode: 2013CrGrD..13.2435K.
45. ↑ Volmer, M.; Weber, A. Z. (1927). "Nucleus Formation in Supersaturated Systems". Zeitschrift für Physikalische Chemie 125: 236–242.
46. ↑ LaMer, Viktor K.; Dinegar, Robert H. (1950). "Theory, Production and Mechanism of Formation of Monodispersed Hydrosols". Journal of the American Chemical Society 72 (11): 4847–4854. doi:10.1021/ja01167a001. Bibcode: 1950JAChS..72.4847L.
47. ↑ 47.0 47.1 Watzky, Murielle A.; Finke, Richard G. (1997). "Transition Metal Nanocluster Formation Kinetic and Mechanistic Studies. A New Mechanism when Hydrogen is the Reductant: Slow, Continuous Nucleation and Fast Autocatalytic Surface Growth". J. Am. Chem. Soc. 119 (43): 10382–10400. doi:10.1021/ja9705102. Bibcode: 1997JAChS.11910382W.
48. ↑ Whitehead, Christopher B.; Özkar, Saim; Finke, Richard G. (2019). "LaMer's 1950 Model for Particle Formation of Instantaneous Nucleation and Diffusion-Controlled Growth: A Historical Look at the Model's Origins, Assumptions, Equations, and Underlying Sulfur Sol Formation Kinetics Data". Chem. Mater. 31 (18): 7116–7132. doi:10.1021/acs.chemmater.9b01273. Bibcode: 2019ChMat..31.7116W.
49. ↑ Whitehead, Christopher B.; Özkar, Saim; Finke, Richard G. (2021). "LaMer's 1950 model for particle formation: a review and critical analysis of its classical nucleation and fluctuation theory basis, of competing models and mechanisms for phase-changes and particle formation, and then of its application to silver halide, semiconductor, metal, and metal-oxide nanoparticles". Mater. Adv. 2: 186–235. doi:10.1039/d0ma00439a.
50. ↑ IUPAC, Compendium of Chemical Terminology, 2nd ed. (the "Gold Book") (1997). Online corrected version:  (2006-) "Ostwald ripening". doi:10.1351/goldbook.O04348
51. ↑ Hornstein, Brooks J.; Finke, Richard G. (2004). "Transition-Metal Nanocluster Kinetic and Mechanistic Studies Emphasizing Nanocluster Agglomeration: Demonstration of a Kinetic Method That Allows Monitoring of All Three Phases of Nanocluster Formation and Aging.". Chem. Mater. 16 (1): 139–150. doi:10.1021/cm034585i. https://figshare.com/articles/journal_contribution/3322351.
52. ↑ Besson, Claire; Finney, Eric E.; Finke, Richard G. (2005). "A Mechanism for Transition-Metal Nanoparticle Self-Assembly.". J. Am. Chem. Soc. 127 (22): 8179–8184. doi:10.1021/ja0504439. PMID 15926847. Bibcode: 2005JAChS.127.8179B.
53. ↑ Besson, Claire; Finney, Eric E.; Finke, Richard G. (2005). "Nanocluster Nucleation, Growth, and Then Agglomeration Kinetic and Mechanistic Studies: A More General, Four-Step Mechanism Involving Double Autocatalysis.". Chem. Mater. 17 (20): 4925–4938. doi:10.1021/cm050207x.
54. ↑ Finney, Eric E.; Finke, Richard G. (2008). "The Four-Step, Double-Autocatalytic Mechanism for Transition-Metal Nanocluster Nucleation, Growth, and Then Agglomeration: Metal, Ligand, Concentration, Temperature, and Solvent Dependency Studies.". Chem. Mater. 20 (5): 1956–1970. doi:10.1021/cm071088j.
55. ↑ Kent, Patrick D.; Mondloch, Joseph E.; Finke, Richard G. (2014). "A Four-Step Mechanism for the Formation of Supported-Nanoparticle Heterogeneous Catalysts in Contact with Solution: The Conversion of Ir(1,5-COD)Cl/γ-Al2O3 to Ir(0)~170/γ-Al2O3". J. Am. Chem. Soc. 136 (5): 1930–1941. doi:10.1021/ja410194r. PMID 24444431.
56. ↑ Thanh, Nguyen T. K.; MacLean, N.; Mahiddine, S. (2014). "Mechanisms of Nucleation and Growth of Nanoparticles in Solution". Chem. Rev. 114 (15): 7610–7630. doi:10.1021/cr400544s. PMID 25003956. https://discovery.ucl.ac.uk/id/eprint/1448058/.
57. ↑ Grammatikopoulos, Panagiotis (2019). "Atomistic modeling of the nucleation and growth of pure and hybrid nanoparticles by cluster beam deposition". Current Opinion in Chemical Engineering 23: 164–173. doi:10.1016/j.coche.2019.04.004. Bibcode: 2019COCE...23..164G.
58. ↑ Buzea, Cristina; Pacheco, Ivan I.; Robbie, Kevin (December 2007). "Nanomaterials and nanoparticles: Sources and toxicity". Biointerphases 2 (4): MR17–MR71. doi:10.1116/1.2815690. PMID 20419892.
59. ↑ ASTM E 2456 06 Standard Terminology Relating to Nanotechnology
60. ↑ "Variable Doping Induces Mechanism Swapping in Electrogenerated Chemiluminescence of Ru(bpy)32+ Core Shell Silica Nanoparticles". J. Am. Chem. Soc. 138 (49): 15935–15942. 2016. doi:10.1021/jacs.6b08239. PMID 27960352. Bibcode: 2016JAChS.13815935V.
61. ↑ Vekilov, Peter G. (2010). "Nucleation". Crystal Growth & Design 10 (12): 5007–5019. doi:10.1021/cg1011633. PMID 21132117. Bibcode: 2010CrGrD..10.5007V.
62. ↑ Thanh, N. T.; MacLean, N.; Mahiddine, S. (2014). "Mechanisms of nucleation and growth of nanoparticles in solution". Chem Rev 114 (15): 7610–7630. doi:10.1021/cr400544s. PMID 25003956. https://discovery.ucl.ac.uk/id/eprint/1448058/.
63. ↑ Gubin, Sergey P. (2009). Magnetic nanoparticles. Wiley-VCH. ISBN 978-3-527-40790-3.
64. ↑ Vollath, Dieter; Fischer, Franz Dieter; Holec, David (23 August 2018). "Surface energy of nanoparticles – influence of particle size and structure". Beilstein Journal of Nanotechnology 9: 2265–2276. doi:10.3762/bjnano.9.211. PMID 30202695.
65. ↑ Jiang, Q.; Liang, L. H.; Zhao, D. S. (July 2001). "Lattice Contraction and Surface Stress of fcc Nanocrystals". The Journal of Physical Chemistry B 105 (27): 6275–6277. doi:10.1021/jp010995n. Bibcode: 2001JPCB..105.6275J.
66. ↑ Courtney, Thomas H. (2000). Mechanical behavior of materials (2nd ed.). Boston: McGraw Hill. ISBN 0-07-028594-2. OCLC 41932585.
67. ↑ Ramos, Manuel; Ortiz-Jordan, Luis; Hurtado-Macias, Abel; Flores, Sergio; Elizalde-Galindo, José T.; Rocha, Carmen; Torres, Brenda; Zarei-Chaleshtori, Maryam et al. (January 2013). "Hardness and Elastic Modulus on Six-Fold Symmetry Gold Nanoparticles" (in en). Materials 6 (1): 198–205. doi:10.3390/ma6010198. PMID 28809302. Bibcode: 2013Mate....6..198R.
68. ↑ Oh, Sang Ho; Legros, Marc; Kiener, Daniel; Dehm, Gerhard (February 2009). "In situ observation of dislocation nucleation and escape in a submicrometre aluminium single crystal". Nature Materials 8 (2): 95–100. doi:10.1038/nmat2370. PMID 19151703. Bibcode: 2009NatMa...8...95O.
69. ↑ Feruz, Yosi; Mordehai, Dan (January 2016). "Towards a universal size-dependent strength of face-centered cubic nanoparticles". Acta Materialia 103: 433–441. doi:10.1016/j.actamat.2015.10.027. Bibcode: 2016AcMat.103..433F.
70. ↑ Kulik, Andrzej; Kis, Andras; Gremaud, Gérard; Hengsberger, Stefan; Luengo, Gustavo; Zysset, Philippe; Forró, László (2007), Bhushan, Bharat, ed., "Nanoscale Mechanical Properties – Measuring Techniques and Applications" (in en), Springer Handbook of Nanotechnology, Springer Handbooks (Springer): pp. 1107–1136, doi:10.1007/978-3-540-29857-1_36, ISBN 978-3-540-29857-1, Bibcode: 2007shnt.book.1107K
71. ↑ 71.0 71.1 71.2 71.3 71.4 71.5 Guo, Dan; Xie, Guoxin; Luo, Jianbin (2014-01-08). "Mechanical properties of nanoparticles: basics and applications". Journal of Physics D: Applied Physics 47 (1). doi:10.1088/0022-3727/47/1/013001. ISSN 0022-3727. Bibcode: 2014JPhD...47a3001G.
72. ↑ 72.0 72.1 Tan, Susheng; Sherman, Robert L.; Ford, Warren T. (2004-08-01). "Nanoscale Compression of Polymer Microspheres by Atomic Force Microscopy". Langmuir 20 (17): 7015–7020. doi:10.1021/la049597c. ISSN 0743-7463. PMID 15301482.
73. ↑ Ouyang, Q.; Ishida, K.; Okada, K. (2001-01-15). "Investigation of micro-adhesion by atomic force microscopy" (in en). Applied Surface Science 169-170 (1–2): 644–648. doi:10.1016/S0169-4332(00)00804-7. ISSN 0169-4332. Bibcode: 2001ApSS..169..644O. https://www.sciencedirect.com/science/article/abs/pii/S0169433200008047.
74. ↑ Larson, Ian; Drummond, Calum J.; Chan, Derek Y. C.; Grieser, Franz (1993-12-01). "Direct force measurements between titanium dioxide surfaces". Journal of the American Chemical Society 115 (25): 11885–11890. doi:10.1021/ja00078a029. ISSN 0002-7863. Bibcode: 1993JAChS.11511885L.
75. ↑ 75.0 75.1 Kappl, Michael; Butt, Hans-Jürgen (2002). "The Colloidal Probe Technique and its Application to Adhesion Force Measurements" (in en). Particle & Particle Systems Characterization 19 (3): 129–143. doi:10.1002/1521-4117(200207)19:3<129::AID-PPSC129>3.0.CO;2-G. ISSN 1521-4117. https://onlinelibrary.wiley.com/doi/abs/10.1002/1521-4117(200207)19:3<129::AID-PPSC129>3.0.CO;2-G.
76. ↑ Casillas, Gilberto; Palomares-Báez, Juan Pedro; Rodríguez-López, José Luis; Luo, Junhang; Ponce, Arturo; Esparza, Rodrigo; Velázquez-Salazar, J. Jesús; Hurtado-Macias, Abel et al. (2012-12-11). "In situ TEM study of mechanical behaviour of twinned nanoparticles". Philosophical Magazine 92 (35): 4437–4453. doi:10.1080/14786435.2012.709951. ISSN 1478-6435. Bibcode: 2012PMag...92.4437C.
77. ↑ 77.0 77.1 Buffat, Ph.; Borel, J.-P. (1976). "Size effect on the melting temperature of gold particles". Physical Review A 13 (6): 2287–2298. doi:10.1103/PhysRevA.13.2287. Bibcode: 1976PhRvA..13.2287B. http://infoscience.epfl.ch/record/100337.
78. ↑ Wu, Jiang; Yu, Peng; Susha, Andrei S.; Sablon, Kimberly A.; Chen, Haiyuan; Zhou, Zhihua; Li, Handong; Ji, Haining et al. (2015-04-01). "Broadband efficiency enhancement in quantum dot solar cells coupled with multispiked plasmonic nanostars". Nano Energy 13: 827–835. doi:10.1016/j.nanoen.2015.02.012. Bibcode: 2015NEne...13..827W.
79. ↑ 79.0 79.1 Taylor, Robert A; Otanicar, Todd; Rosengarten, Gary (2012). "Nanofluid-based optical filter optimization for PV/T systems". Light: Science & Applications 1 (10). doi:10.1038/lsa.2012.34. Bibcode: 2012LSA.....1E..34T.
80. ↑ 80.0 80.1 Taylor, Robert A.; Otanicar, Todd P.; Herukerrupu, Yasitha; Bremond, Fabienne; Rosengarten, Gary; Hawkes, Evatt R.; Jiang, Xuchuan; Coulombe, Sylvain (2013). "Feasibility of nanofluid-based optical filters". Applied Optics 52 (7): 1413–22. doi:10.1364/AO.52.001413. PMID 23458793. Bibcode: 2013ApOpt..52.1413T. https://www.researchgate.net/publication/235786101.
81. ↑ Taylor, Robert A; Phelan, Patrick E; Otanicar, Todd P; Adrian, Ronald; Prasher, Ravi (2011). "Nanofluid optical property characterization: Towards efficient direct absorption solar collectors". Nanoscale Research Letters 6 (1): 225. doi:10.1186/1556-276X-6-225. PMID 21711750. Bibcode: 2011NRL.....6..225T.
82. ↑ 82.0 82.1 "Electrogenerated chemiluminescence from metal complexes-based nanoparticles for highly sensitive sensors applications". Coordination Chemistry Reviews 367: 65–81. 2018. doi:10.1016/j.ccr.2018.04.011.
83. ↑ 83.0 83.1 83.2 Taylor, Robert; Coulombe, Sylvain; Otanicar, Todd; Phelan, Patrick; Gunawan, Andrey; Lv, Wei; Rosengarten, Gary; Prasher, Ravi et al. (2013). "Small particles, big impacts: A review of the diverse applications of nanofluids". Journal of Applied Physics 113 (1): 011301–011301–19. doi:10.1063/1.4754271. Bibcode: 2013JAP...113a1301T. https://www.researchgate.net/publication/257069577.
84. ↑ 84.0 84.1 Ghosh Chaudhuri, Rajib; Paria, Santanu (11 April 2012). "Core/Shell Nanoparticles: Classes, Properties, Synthesis Mechanisms, Characterization, and Applications". Chemical Reviews 112 (4): 2373–2433. doi:10.1021/cr100449n. PMID 22204603.
85. ↑ Loo, Jacky Fong-Chuen; Chien, Yi-Hsin; Yin, Feng; Kong, Siu-Kai; Ho, Ho-Pui; Yong, Ken-Tye (December 2019). "Upconversion and downconversion nanoparticles for biophotonics and nanomedicine". Coordination Chemistry Reviews 400. doi:10.1016/j.ccr.2019.213042.
86. ↑ Yu, Peng; Yao, Yisen; Wu, Jiang; Niu, Xiaobin; Rogach, Andrey L.; Wang, Zhiming (December 2017). "Effects of Plasmonic Metal Core -Dielectric Shell Nanoparticles on the Broadband Light Absorption Enhancement in Thin Film Solar Cells". Scientific Reports 7 (1): 7696. doi:10.1038/s41598-017-08077-9. PMID 28794487. Bibcode: 2017NatSR...7.7696Y.
87. ↑ Whitesides, G.M. (1991). "Molecular Self-Assembly and Nanochemistry: A Chemical Strategy for the Synthesis of Nanostructures". Science 254 (5036): 1312–1319. doi:10.1126/science.1962191. PMID 1962191. Bibcode: 1991Sci...254.1312W.
88. ↑ Dabbs D. M, Aksay I.A.; Aksay (2000). "Self-Assembled Ceramics". Annu. Rev. Phys. Chem. 51: 601–22. doi:10.1146/annurev.physchem.51.1.601. PMID 11031294. Bibcode: 2000ARPC...51..601D.
89. ↑ 89.0 89.1 Tankard, Rikke Egeberg; Romeggio, Filippo; Akazawa, Stefan Kei; Krabbe, Alexander; Sloth, Olivia Fjord; Secher, Niklas Mørch; Colding-Fagerholt, Sofie; Helveg, Stig et al. (2024). "Stable mass-selected AuTiOx nanoparticles for CO oxidation". Physical Chemistry Chemical Physics 26 (12): 9253–9263. doi:10.1039/D4CP00211C. PMID 38445363. Bibcode: 2024PCCP...26.9253T.
90. ↑ Anandkumar, Mariappan; Bhattacharya, Saswata; Deshpande, Atul Suresh (2019). "Low temperature synthesis and characterization of single phase multi-component fluorite oxide nanoparticle sols". RSC Advances 9 (46): 26825–26830. doi:10.1039/C9RA04636D. PMID 35528557. Bibcode: 2019RSCAd...926825A.
91. ↑ Hosseini, Mansoure; Mashreghi, Mansour; Eshghi, Hossein (2016). "Biosynthesis and antibacterial activity of gold nanoparticles coated with reductase enzymes". Micro & Nano Letters 11 (9): 484–489. doi:10.1049/mnl.2016.0065. https://digital-library.theiet.org/content/journals/10.1049/mnl.2016.0065.
92. ↑ Saito, Tsuguyuki; Kimura, Satoshi; Nishiyama, Yoshiharu; Isogai, Akira (August 2007). "Cellulose Nanofibers Prepared by TEMPO-Mediated Oxidation of Native Cellulose". Biomacromolecules 8 (8): 2485–2491. doi:10.1021/bm0703970. PMID 17630692.
93. ↑ Fan, Yimin; Saito, Tsuguyuki; Isogai, Akira (17 March 2010). "Individual chitin nano-whiskers prepared from partially deacetylated α-chitin by fibril surface cationization". Carbohydrate Polymers 79 (4): 1046–1051. doi:10.1016/j.carbpol.2009.10.044.
94. ↑ Habibi, Youssef (2014). "Key advances in the chemical modification of nanocelluloses". Chem. Soc. Rev. 43 (5): 1519–1542. doi:10.1039/c3cs60204d. PMID 24316693. Bibcode: 2014CSRev..43.1519H.
95. ↑ Jiayin, Guo; Xiaobao, Fan; Dolbec, Richard; Siwen, Xue; Jurewicz, Jerzy; Boulos, Maher (April 2010). "Development of Nanopowder Synthesis Using Induction Plasma". Plasma Science and Technology 12 (2): 188–199. doi:10.1088/1009-0630/12/2/12. ISSN 1009-0630. Bibcode: 2010PlST...12..188G.
96. ↑ 96.0 96.1 Granqvist, C. G.; Buhrman, R. A. (1976). "Ultrafine metal particles". Journal of Applied Physics 47 (5): 2200 2219. doi:10.1063/1.322870. Bibcode: 1976JAP....47.2200G.
97. ↑ Hahn, H.; Averback, R. S. (1990). "The production of nanocrystalline powders by magnetron sputtering". Journal of Applied Physics 67 (2): 1113 1115. doi:10.1063/1.345798. Bibcode: 1990JAP....67.1113H.
98. ↑ Wang, Jian-Ping; Bai, Jianmin (2005). "High-magnetic-moment core-shell-type FeCo Au AgFeCo Au Ag nanoparticles". Appl. Phys. Lett. 87: 152502. doi:10.1063/1.2089171.
99. ↑ 99.0 99.1 Hennes, M.; Lotnyk, A.; Mayr, S. G. (2014). "Plasma-assisted synthesis and high-resolution characterization of anisotropic elemental and bimetallic core shell magnetic nanoparticles". Beilstein J. Nanotechnol. 5: 466–475. doi:10.3762/bjnano.5.54. PMID 24778973.
100. ↑ Llamosa, D.; Ruano, M.; Martínez, L.; Mayoral, A.; Roman, E.; García-Hernández, M.; Huttel, Y. (2014). "The ultimate step towards a tailored engineering of core@shell and core@shell@shell nanoparticles". Nanoscale 6 (22): 13483–13486. doi:10.1039/c4nr02913e. PMID 25180699. Bibcode: 2014Nanos...613483L.
101. ↑ Michelakaki, Irini; Boukos, Nikos; Dragatogiannis, Dimitrios A; Stathopoulos, Spyros; Charitidis, Costas A; Tsoukalas, Dimitris (27 June 2018). "Synthesis of hafnium nanoparticles and hafnium nanoparticle films by gas condensation and energetic deposition". Beilstein Journal of Nanotechnology 9: 1868–1880. doi:10.3762/bjnano.9.179. PMID 30013881.
102. ↑ Belloni, J.; Mostafavi, M.; Remita, H.; Marignier, J. L.; Delcourt, A. M. O. (1998). "Radiation-induced synthesis of mono- and multi-metallic clusters and nanocolloids". New Journal of Chemistry 22 (11): 1239 1255. doi:10.1039/A801445K. Bibcode: 1998NJCh...22.1239B.
103. ↑ Brinker, C.J.; Scherer, G.W. (1990). Sol-Gel Science: The Physics and Chemistry of Sol-Gel Processing. Academic Press. ISBN 978-0-12-134970-7.
104. ↑ Hench, L. L.; West, J. K. (1990). "The sol-gel process". Chemical Reviews 90: 33–72. doi:10.1021/cr00099a003.
105. ↑ Klein, L. (1994). Sol-Gel Optics: Processing and Applications. Springer Verlag. ISBN 978-0-7923-9424-2. https://books.google.com/books?id=wH11Y4UuJNQC. Retrieved 6 December 2016.
106. ↑ Corriu, Robert; Anh, Nguyên Trong (2009). Molecular Chemistry of Sol-Gel Derived Nanomaterials. John Wiley and Sons. ISBN 978-0-470-72117-9. https://books.google.com/books?id=TMr5XeZXlL0C&pg=PA75.
107. ↑ Sadri, R. (15 October 2017). "Study of environmentally friendly and facile functionalization of graphene nanoplatelet and its application in convective heat transfer". Energy Conversion and Management 150: 26–36. doi:10.1016/j.enconman.2017.07.036. Bibcode: 2017ECM...150...26S.
108. ↑ Prime, KL; Whitesides, GM (1991). "Self-assembled organic monolayers: model systems for studying adsorption of proteins at surfaces". Science 252 (5009): 1164–7. doi:10.1126/science.252.5009.1164. PMID 2031186. Bibcode: 1991Sci...252.1164P.
109. ↑ Liu, Wenhao; Greytak, Andrew B.; Lee, Jungmin; Wong, Cliff R.; Park, Jongnam; Marshall, Lisa F.; Jiang, Wen; Curtin, Peter N. et al. (20 January 2010). "Compact Biocompatible Quantum Dots via RAFT-Mediated Synthesis of Imidazole-Based Random Copolymer Ligand". Journal of the American Chemical Society 132 (2): 472–483. doi:10.1021/ja908137d. PMID 20025223. Bibcode: 2010JAChS.132..472L.
110. ↑ Hock, N; Racaniello, GF; Aspinall, S; Denora, N; Khutoryanskiy, V; Bernkop-Schnürch, A (2022). "Thiolated Nanoparticles for Biomedical Applications: Mimicking the Workhorses of our Body". Advanced Science 9 (1). doi:10.1002/advs.202102451. PMID 34773391. Bibcode: 2022AdvSc...902451H.
111. ↑ "Nanocrystal targeting in vivo". Proceedings of the National Academy of Sciences of the United States of America 99 (20): 12617–12621. 2002. doi:10.1073/pnas.152463399. PMID 12235356. Bibcode: 2002PNAS...9912617A.
112. ↑ Hoshino, A; Fujioka, K; Oku, T; Nakamura, S; Suga, M; Yamaguchi, Y; Suzuki, K; Yasuhara, M et al. (2004). "Quantum dots targeted to the assigned organelle in living cells". Microbiology and Immunology 48 (12): 985–94. doi:10.1111/j.1348-0421.2004.tb03621.x. PMID 15611617.
113. ↑ Suzuki, KG; Fujiwara, TK; Edidin, M; Kusumi, A (2007). "Dynamic recruitment of phospholipase C at transiently immobilized GPI-anchored receptor clusters induces IP3 Ca2+ signaling: single-molecule tracking study 2". The Journal of Cell Biology 177 (4): 731–42. doi:10.1083/jcb.200609175. PMID 17517965.
114. ↑ Sung, KM; Mosley, DW; Peelle, BR; Zhang, S; Jacobson, JM (2004). "Synthesis of monofunctionalized gold nanoparticles by fmoc solid-phase reactions". Journal of the American Chemical Society 126 (16): 5064–5. doi:10.1021/ja049578p. PMID 15099078. Bibcode: 2004JAChS.126.5064S.
115. ↑ Fu, A; Micheel, CM; Cha, J; Chang, H; Yang, H; Alivisatos, AP (2004). "Discrete nanostructures of quantum dots/Au with DNA". Journal of the American Chemical Society 126 (35): 10832–3. doi:10.1021/ja046747x. PMID 15339154. Bibcode: 2004JAChS.12610832F.
116. ↑ Howarth, M; Liu, W; Puthenveetil, S; Zheng, Y; Marshall, LF; Schmidt, MM; Wittrup, KD; Bawendi, MG et al. (2008). "Monovalent, reduced-size quantum dots for imaging receptors on living cells". Nature Methods 5 (5): 397–9. doi:10.1038/nmeth.1206. PMID 18425138.
117. ↑ Campbell, Charles T. (2013-08-20). "The Energetics of Supported Metal Nanoparticles: Relationships to Sintering Rates and Catalytic Activity". Accounts of Chemical Research 46 (8): 1712–1719. doi:10.1021/ar3003514. ISSN 0001-4842. PMID 23607711.
118. ↑ "Nanoparticles play at being red blood cells". http://physicsworld.com/cws/article/news/46344.
119. ↑ Onoda, G.Y. Jr., ed (1979). Ceramic Processing Before Firing. New York: Wiley & Sons. ISBN 978-0-471-65410-0.
120. ↑ Aksay, I.A.; Lange, F.F.; Davis, B.I. (1983). "Uniformity of Al2O3-ZrO2 Composites by Colloidal Filtration". J. Am. Ceram. Soc. 66 (10): C 190. doi:10.1111/j.1151-2916.1983.tb10550.x.
121. ↑ Franks, G.V.; Lange, F.F. (1996). "Plastic-to-Brittle Transition of Saturated, Alumina Powder Compacts". J. Am. Ceram. Soc. 79 (12): 3161 3168. doi:10.1111/j.1151-2916.1996.tb08091.x.
122. ↑ Evans, A.G.; Davidge, R.W. (1969). "The strength and fracture of fully dense polycrystalline magnesium oxide". Phil. Mag. 20 (164): 373 388. doi:10.1080/14786436908228708. Bibcode: 1969PMag...20..373E.
123. ↑ Evans, A. G.; Davidge, R. W. (1970). "The strength and oxidation of reaction-sintered silicon nitride". J. Mater. Sci. 5 (4): 314 325. doi:10.1007/BF02397783. Bibcode: 1970JMatS...5..314E.
124. ↑ Lange, F. F.; Metcalf, M. (June 1983). "Processing-Related Fracture Origins: II, Agglomerate Motion and Cracklike Internal Surfaces Caused by Differential Sintering". Journal of the American Ceramic Society 66 (6): 398–406. doi:10.1111/j.1151-2916.1983.tb10069.x.
125. ↑ Evans, A.G. (1987). "Considerations of Inhomogeneity Effects in Sintering". J. Am. Ceram. Soc. 65 (10): 497–501. doi:10.1111/j.1151-2916.1982.tb10340.x.
126. ↑ 126.0 126.1 126.2 126.3 126.4 126.5 126.6 Hassellöv, Martin; Readman, James W.; Ranville, James F.; Tiede, Karen (July 2008). "Nanoparticle analysis and characterization methodologies in environmental risk assessment of engineered nanoparticles". Ecotoxicology 17 (5): 344–361. doi:10.1007/s10646-008-0225-x. PMID 18483764. Bibcode: 2008Ecotx..17..344H.
127. ↑ Powers, Kevin W.; Palazuelos, Maria; Moudgil, Brij M.; Roberts, Stephen M. (January 2007). "Characterization of the size, shape, and state of dispersion of nanoparticles for toxicological studies". Nanotoxicology 1 (1): 42–51. doi:10.1080/17435390701314902.
128. ↑ 128.0 128.1 128.2 128.3 128.4 Tiede, Karen; Boxall, Alistair B.A.; Tear, Steven P.; Lewis, John; David, Helen; Hassellöv, Martin (July 2008). "Detection and characterization of engineered nanoparticles in food and the environment". Food Additives & Contaminants: Part A 25 (7): 795–821. doi:10.1080/02652030802007553. PMID 18569000. https://hal.archives-ouvertes.fr/hal-00577384/file/PEER_stage2_10.1080%2F02652030802007553.pdf.
129. ↑ Linsinger, Thomas P.J.; Roebben, Gert; Solans, Conxita; Ramsch, Roland (January 2011). "Reference materials for measuring the size of nanoparticles". TrAC Trends in Analytical Chemistry 30 (1): 18–27. doi:10.1016/j.trac.2010.09.005.
130. ↑ Rawat, Pankaj Singh; Srivastava, R.C.; Dixit, Gagan; Asokan, K. (2020). "Structural, functional and magnetic ordering modifications in graphene oxide and graphite by 100 MeV gold ion irradiation". Vacuum 182. doi:10.1016/j.vacuum.2020.109700. Bibcode: 2020Vacuu.18209700R. https://linkinghub.elsevier.com/retrieve/pii/S0042207X20305613.
131. ↑ Zoroddu, Maria Antonietta; Medici, Serenella; Ledda, Alessia; Nurchi, Valeria Marina; Peana, Joanna I. Lachowicz and Massimiliano; Peana, M (31 October 2014). "Toxicity of Nanoparticles". Current Medicinal Chemistry 21 (33): 3837–3853. doi:10.2174/0929867321666140601162314. PMID 25306903.
132. ↑ Crisponi, G.; Nurchi, V.M.; Lachowicz, J.; Peana, M.; Medici, S.; Zoroddu, M.A. (2017). Chapter 18 - Toxicity of Nanoparticles: Etiology and Mechanisms, in Antimicrobial Nanoarchitectonics. ELSEVIER. pp. 511 546. doi:10.1016/B978-0-323-52733-0.00018-5. ISBN 978-0-323-52733-0.
133. ↑ Mnyusiwalla, Anisa; Daar, Abdallah S; Singer, Peter A (1 March 2003). "'Mind the gap': science and ethics in nanotechnology". Nanotechnology 14 (3): R9–R13. doi:10.1088/0957-4484/14/3/201. http://pdfs.semanticscholar.org/4710/5d71e141ddba8ff0e1d3a4644cea1a3d684a.pdf.
134. ↑ "Toxic Nanoparticles Might be Entering Human Food Supply, MU Study Finds". University of Missouri. 22 August 2013. http://munews.missouri.edu/news-releases/2013/0822-toxic-nanoparticles-might-be-entering-human-food-supply-mu-study-finds/.
135. ↑ Ying, Jackie (2001). Nanostructured Materials. New York: Academic Press. ISBN 978-0-12-744451-2. https://books.google.com/books?id=_pbtbJwkj5YC. Retrieved 6 December 2016.
136. ↑ "The aggregation of striped nanoparticles in mixed phospholipid bilayers". Nanoscale 12 (8): 4868–81. 2020. doi:10.1039/c9nr07106g. PMID 31916561. https://figshare.com/articles/The_Aggregation_of_Striped_Nanoparticles_in_Mixed_Phospholipid_Bilayers/9438611.
137. ↑ Nanotechnologies: 6. What are potential harmful effects of nanoparticles? europa.eu
138. ↑ Thake, T.H.F; Webb, J.R; Nash, A.; Rappoport, J.Z.; Notman, R. (2013). "Permeation of polystyrene nanoparticles across model lipid bilayer membranes". Soft Matter 9 (43): 10265 10274. doi:10.1039/c3sm51225h. Bibcode: 2013SMat....910265T.
139. ↑ Greulich, C.; Diendorf, J.; Simon, T.; Eggeler, G.; Epple, M.; Köller, M. (January 2011). "Uptake and intracellular distribution of silver nanoparticles in human mesenchymal stem cells". Acta Biomaterialia 7 (1): 347–354. doi:10.1016/j.actbio.2010.08.003. PMID 20709196.
140. ↑ Hanley, Cory; Thurber, Aaron; Hanna, Charles; Punnoose, Alex; Zhang, Jianhui; Wingett, Denise G. (December 2009). "The Influences of Cell Type and ZnO Nanoparticle Size on Immune Cell Cytotoxicity and Cytokine Induction". Nanoscale Research Letters 4 (12): 1409–1420. doi:10.1007/s11671-009-9413-8. PMID 20652105. Bibcode: 2009NRL.....4.1409H.
141. ↑ "Assessing the safety and cost-effectiveness of early nanodrugs". Journal of Law and Medicine 16 (5): 822–45. 2009. PMID 19554862.
142. ↑ Benson, Heather AE; Sarveiya, Vikram; Risk, Stacey; Roberts, Michael S (2005). "Influence of anatomical site and topical formulation on skin penetration of sunscreens". Therapeutics and Clinical Risk Management 1 (3): 209–218. PMID 18360561.
143. ↑ Howard, V. (2009). "Statement of Evidence: Particulate Emissions and Health (An Bord Plenala, on Proposed Ringaskiddy Waste-to-Energy Facility)." Retrieved 26 April 2011.
144. ↑ Pieters, N (March 2015). "Blood Pressure and Same-Day Exposure to Air Pollution at School: Associations with Nano-Sized to Coarse PM in Children.". Environmental Health Perspectives 123 (7): 737–742. doi:10.1289/ehp.1408121. PMID 25756964. Bibcode: 2015EnvHP.123..737P.
145. ↑ Mapanao, Ana Katrina; Giannone, Giulia; Summa, Maria; Ermini, Maria Laura; Zamborlin, Agata; Santi, Melissa; Cassano, Domenico; Bertorelli, Rosalia et al. (2020). "Biokinetics and clearance of inhaled gold ultrasmall-in-nano architectures". Nanoscale Advances 2 (9): 3815–3820. doi:10.1039/D0NA00521E. PMID 36132776. Bibcode: 2020NanoA...2.3815M.
146. ↑ Cassano, Domenico; Mapanao, Ana-Katrina; Summa, Maria; Vlamidis, Ylea; Giannone, Giulia; Santi, Melissa; Guzzolino, Elena; Pitto, Letizia et al. (21 October 2019). "Biosafety and Biokinetics of Noble Metals: The Impact of Their Chemical Nature". ACS Applied Bio Materials 2 (10): 4464–4470. doi:10.1021/acsabm.9b00630. PMID 35021406.
147. ↑ 147.0 147.1 147.2 147.3 147.4 147.5 "Nanomaterials EPA is Assessing". Environmental Protection Agency. http://www.epa.gov/nanoscience/quickfinder/nanomaterials.htm. This article incorporates text from a publication now in the public domain:
148. ↑ Susan Wayland and Penelope Fenner-Crisp. Reducing Pesticide Risks: A Half Century of Progress.  EPA Alumni Association. March 2016.
149. ↑ Tai, Yifan; Midgley, Adam C. (2022-03-29), "Nanoparticles for Cardiovascular Medicine: Trends in Myocardial Infarction Therapy" (in en), Nanopharmaceuticals in Regenerative Medicine (Boca Raton: CRC Press): pp. 303–327, doi:10.1201/9781003153504-17, ISBN 978-1-003-15350-4, https://www.taylorfrancis.com/books/9781003153504/chapters/10.1201/9781003153504-17, retrieved 2022-05-23
150. ↑ Gu, Xurui; Liu, Zhen; Tai, Yifan; Zhou, Ling-yun; Liu, Kun; Kong, Deling; Midgley, Adam C; Zuo, Xiao-cong (2022-04-01). "Hydrogel and nanoparticle carriers for kidney disease therapy: trends and recent advancements". Progress in Biomedical Engineering 4 (2): 022006. doi:10.1088/2516-1091/ac6e18. ISSN 2516-1091. PMID 41287232. Bibcode: 2022PBioE...4b2006G. https://iopscience.iop.org/article/10.1088/2516-1091/ac6e18.
151. ↑ Hubler, A.; Osuagwu, O. (2010). "Digital quantum batteries: Energy and information storage in nanovacuum tube arrays". Complexity 15 (5): 48–55. doi:10.1002/cplx.20306.
152. ↑ Stephenson, C.; Hubler, A. (2015). "Stability and conductivity of self assembled wires in a transverse electric field". Sci. Rep. 5. doi:10.1038/srep15044. PMID 26463476. Bibcode: 2015NatSR...515044S.
153. ↑ Hubler, A.; Lyon, D. (2013). "Gap size dependence of the dielectric strength in nano vacuum gaps". IEEE Transactions on Dielectrics and Electrical Insulation 20 (4): 1467 1471. doi:10.1109/TDEI.2013.6571470. Bibcode: 2013ITDEI..20.1467L.
154. ↑ Omidvar, A. (2016). "Metal-enhanced fluorescence of graphene oxide by palladium nanoparticles in the blue-green part of the spectrum". Chinese Physics B 25 (11). doi:10.1088/1674-1056/25/11/118102. Bibcode: 2016ChPhB..25k8102O.
155. ↑ Rashidian V, M.R. (2017). "Investigating the extrinsic size effect of palladium and gold spherical nanoparticles". Optical Materials 64: 413–420. doi:10.1016/j.optmat.2017.01.014. Bibcode: 2017OptMa..64..413R.
156. ↑ Omidvar, A. (2018). "Enhancing the nonlinear optical properties of graphene oxide by repairing with palladium nanoparticles". Physica E: Low-dimensional Systems and Nanostructures 103: 239–245. doi:10.1016/j.physe.2018.06.013. Bibcode: 2018PhyE..103..239O.
157. ↑ Hewakuruppu, Y. L.; Dombrovsky, L. A.; Chen, C.; Timchenko, V.; Jiang, X.; Baek, S.; Taylor, R. A. (2013). "Plasmonic "pump probe" method to study semi-transparent nanofluids". Applied Optics 52 (24): 6041–50. doi:10.1364/AO.52.006041. PMID 24085009. Bibcode: 2013ApOpt..52.6041H.
158. ↑ Duarte, F. J.; James, R. O. (2003). "Tunable solid-state lasers incorporating dye-doped polymer-nanoparticle gain media". Opt. Lett. 28 (21): 2088–90. doi:10.1364/OL.28.002088. PMID 14587824. Bibcode: 2003OptL...28.2088D.
159. ↑ Singh, BN; Prateeksha, Gupta VK; Chen, J; Atanasov, AG (2017). "Organic Nanoparticle-Based Combinatory Approaches for Gene Therapy". Trends Biotechnol 35 (12): 1121–1124. doi:10.1016/j.tibtech.2017.07.010. PMID 28818304. .
160. ↑ Wang, Zhenming; Wang, Zhefeng; Lu, William Weijia; Zhen, Wanxin; Yang, Dazhi; Peng, Songlin (October 2017). "Novel biomaterial strategies for controlled growth factor delivery for biomedical applications". NPG Asia Materials 9 (10): e435. doi:10.1038/am.2017.171.
161. ↑ Jóźwik, Artur; Marchewka, Joanna; Strzałkowska, Nina; Horbańczuk, Jarosław; Szumacher-Strabel, Małgorzata; Cieślak, Adam; Lipińska-Palka, Paulina; Józefiak, Damian et al. (11 May 2018). "The Effect of Different Levels of Cu, Zn and Mn Nanoparticles in Hen Turkey Diet on the Activity of Aminopeptidases". Molecules 23 (5): 1150. doi:10.3390/molecules23051150. PMID 29751626.
162. ↑ "The Textiles Nanotechnology Laboratory". nanotextiles.human.cornell.edu. https://nanotextiles.human.cornell.edu/.
163. ↑ Evans, B. (January 2018). "Nano-particle drag prediction at low Reynolds number using a direct Boltzmann–BGK solution approach". Journal of Computational Physics 352: 123–141. doi:10.1016/j.jcp.2017.09.038. Bibcode: 2018JCoPh.352..123E. https://cronfa.swan.ac.uk/Record/cronfa35652/Download/0035652-04102017103312.pdf.
164. ↑ Hafezi, F.; Ransing, R. S.; Lewis, R. W. (14 September 2017). "The calculation of drag on nano-cylinders: The calculation of drag on nano-cylinders". International Journal for Numerical Methods in Engineering 111 (11): 1025–1046. doi:10.1002/nme.5489. Bibcode: 2017IJNME.111.1025H. https://cronfa.swan.ac.uk/Record/cronfa31407/Download/0031407-18122016172609.pdf.
165. ↑ Cheraghian, Goshtasp; Wistuba, Michael P. (December 2020). "Ultraviolet aging study on bitumen modified by a composite of clay and fumed silica nanoparticles". Scientific Reports 10 (1): 11216. doi:10.1038/s41598-020-68007-0. PMID 32641741. Bibcode: 2020NatSR..1011216C.
166. ↑ Mendes, B.B., Conniot, J., Avital, A. et al. Nanodelivery of nucleic acids. Nat Rev Methods Primers 2, 24 (2022). https://doi.org/10.1038/s43586-022-00104-y
167. ↑ Gavas, Shreelaxmi; Quazi, Sameer; Karpiński, Tomasz M. (December 2021). "Nanoparticles for Cancer Therapy: Current Progress and Challenges" (in en). Nanoscale Research Letters 16 (1). doi:10.1186/s11671-021-03628-6. ISSN 1556-276X. PMID 34866166. Bibcode: 2021NRL....16..173G.
168. ↑ Bazak, Remon; Houri, Mohamad; El Achy, Samar; Kamel, Serag; Refaat, Tamer (May 2015). "Cancer active targeting by nanoparticles: a comprehensive review of literature" (in en). Journal of Cancer Research and Clinical Oncology 141 (5): 769–784. doi:10.1007/s00432-014-1767-3. ISSN 0171-5216. PMID 25005786.
169. ↑ Deirram, Nayeleh; Zhang, Changhe; Kermaniyan, Sarah S.; Johnston, Angus P. R.; Such, Georgina K. (May 2019). "pH-Responsive Polymer Nanoparticles for Drug Delivery" (in en). Macromolecular Rapid Communications 40 (10). doi:10.1002/marc.201800917. ISSN 1022-1336. PMID 30835923. https://onlinelibrary.wiley.com/doi/10.1002/marc.201800917.
170. ↑ Karimi, Mahdi; Sahandi Zangabad, Parham; Ghasemi, Alireza; Amiri, Mohammad; Bahrami, Mohsen; Malekzad, Hedieh; Ghahramanzadeh Asl, Hadi; Mahdieh, Zahra et al. (2016-08-24). "Temperature-Responsive Smart Nanocarriers for Delivery Of Therapeutic Agents: Applications and Recent Advances" (in en). ACS Applied Materials & Interfaces 8 (33): 21107–21133. doi:10.1021/acsami.6b00371. ISSN 1944-8244. PMID 27349465. Bibcode: 2016AAMI....821107K.
171. ↑ Munima, Haque; Md Salman, Shakil; Kazi Mustafa, Mahmud (2023-03-22). "The Promise of Nanoparticles-Based Radiotherapy in Cancer Treatment". Cancers 15 (6): 1892. doi:10.3390/cancers15061892. PMID 36980778. Bibcode: 2023Cance..15.1892H.
172. ↑ "Sunscreen". U.S. Food and Drug Administration. https://www.fda.gov/Radiation-EmittingProducts/RadiationEmittingProductsandProcedures/Tanning/ucm116445.htm.
173. ↑ Mitchnick, Mark A.; Fairhurst, David; Pinnell, Sheldon R. (January 1999). "Microfine zinc oxide (Z-Cote) as a photostable UVA/UVB sunblock agent". Journal of the American Academy of Dermatology 40 (1): 85–90. doi:10.1016/s0190-9622(99)70532-3. PMID 9922017.
174. ↑ Heim, J; Felder, E; Tahir, MN; Kaltbeitzel, A; Heinrich, UR; Brochhausen, C; Mailänder, V; Tremel, W et al. (21 May 2015). "Genotoxic effects of zinc oxide nanoparticles.". Nanoscale 7 (19): 8931–8. doi:10.1039/c5nr01167a. PMID 25916659. Bibcode: 2015Nanos...7.8931H.
175. ↑ Wang, Bing; Zhang, Yuying; Mao, Zhengwei; Yu, Dahai; Gao, Changyou (1 August 2014). "Toxicity of ZnO Nanoparticles to Macrophages Due to Cell Uptake and Intracellular Release of Zinc Ions". Journal of Nanoscience and Nanotechnology 14 (8): 5688–5696. doi:10.1166/jnn.2014.8876. PMID 25935990.
176. ↑ Gosens, I; Kermanizadeh, A; Jacobsen, NR; Lenz, AG; Bokkers, B; de Jong, WH; Krystek, P; Tran, L et al. (2015). "Comparative hazard identification by a single dose lung exposure of zinc oxide and silver nanomaterials in mice.". PLOS ONE 10 (5). doi:10.1371/journal.pone.0126934. PMID 25966284. Bibcode: 2015PLoSO..1026934G.
177. ↑ Hanagata, N; Morita, H (2015). "Calcium ions rescue human lung epithelial cells from the toxicity of zinc oxide nanoparticles.". The Journal of Toxicological Sciences 40 (5): 625–35. doi:10.2131/jts.40.625. PMID 26354379.
178. ↑ Kim, Young Hee; Kwak, Kyung A; Kim, Tae Sung; Seok, Ji Hyeon; Roh, Hang Sik; Lee, Jong-Kwon; Jeong, Jayoung; Meang, Eun Ho et al. (30 June 2015). "Retinopathy Induced by Zinc Oxide Nanoparticles in Rats Assessed by Micro-computed Tomography and Histopathology". Toxicological Research 31 (2): 157–163. doi:10.5487/TR.2015.31.2.157. PMID 26191382. Bibcode: 2015ToxRe..31..157K.
179. ↑ Moridian, M.; Khorsandi, L.; Talebi, A. R. (2015). "Morphometric and stereological assessment of the effects of zinc oxide nanoparticles on the mouse testicular tissue". Bratislava Medical Journal 116 (5): 321–325. doi:10.4149/bll_2015_060. PMID 25924642.
180. ↑ Salata, OV (2004). "Applications of nanoparticles in biology and medicine". Journal of Nanobiotechnology 2 (1). doi:10.1186/1477-3155-2-3. PMID 15119954.

## Further reading

* Jackie Y. Ying (2001). Nanostructured Materials. Academic Press. pp. 5–. ISBN 978-0-12-744451-2. https://books.google.com/books?id=_pbtbJwkj5YC&pg=PA5.
* Nanoparticles Used in Solar Energy Conversion (ScienceDaily).
* "Nanoparticles: An occupational hygiene review" by RJ Aitken and others. Health and Safety Executive Research Report 274/2004
* "EMERGNANO: A review of completed and near completed environment, health and safety research on nanomaterials and nanotechnology" by RJ Aitken and others.
* High transmission Tandem DMA for nanoparticle studies by SEADM, 2014.

## External links

| Wikibooks has a book on the topic of: Nanotechnology

|

* Nanohedron.com images of nanoparticles
* Lectures on All Phases of Nanoparticle Science and Technology
* ENPRA – Risk Assessment of Engineered NanoParticles[Usurped!] EC FP7 Project led by the Institute of Occupational Medicine

* v
* t
* e

Nanotechnology

Overview|

* History
* Organizations
* Popular culture
* Outline

Impact and applications|

* Nanomedicine
* Nanotoxicology
* Green nanotechnology
* Regulation

Nanomaterials|

* Fullerenes
* Carbon nanotubes
* Nanoparticles

Molecular self-assembly|

* Self-assembled monolayer
* Supramolecular assembly
* DNA nanotechnology

Nanoelectronics|

* Molecular scale electronics
* Nanolithography

Scanning probe microscopy|

* Atomic force microscope
* Scanning tunneling microscope

Molecular nanotechnology|

* Molecular assembler
* Nanorobotics
* Mechanosynthesis

* Category
* Commons
*   *

Template:Aerosol terminology

* v
* t
* e

Contrast media (V08)

X-ray and CT|

| Iodinated,
Water soluble|

| Nephrotropic,
high osmolar|

* Diatrizoic acid#
* Metrizoic acid
* Iodamide
* Iotalamic acid
* Ioxitalamic acid
* Ioglicic acid
* Acetrizoic acid
* Iocarmic acid
* Methiodal
* Diodone

|

Nephrotropic,
low osmolar|

* Metrizamide
* Iohexol#
* Ioxaglic acid
* Iopamidol
* Iopromide
* Iotrolan
* Ioversol
* Iopentol
* Iodixanol
* Iomeprol
* Iobitridol
* Ioxilan

Hepatotropic|

* Iodoxamic acid
* Iotroxic acid
* Ioglycamic acid
* Adipiodone
* Iobenzamic acid
* Iopanoic acid
* Iocetamic acid
* Sodium iopodate
* Tyropanoic acid
* Calcium iopodate

Iodinated,
Water insoluble|

* Ethyl esters of iodised fatty acids
* Iopydol
* Propyliodone
* Iofendylate‡
* Lipiodol

Non-iodinated|

* Barium sulfate#

MRI|

| Paramagnetic|

* Gadolinium-based: Gadobenic acid
* Gadobutrol
* Gadodiamide
* Gadofosveset
* Gadolinium
* Gadopentetic acid
* Gadoteric acid
* Gadoteridol
* Gadoversetamide
* Gadoxetic acid

* Other: Ferric ammonium citrate
* Mangafodipir‡

|

Superparamagnetic|

* Ferumoxsil
* Ferristene
* Iron oxide, nanoparticles

Other|

* Perflubron

Ultrasound|

* Microspheres of human albumin
* Microparticles of galactose
* Perflenapent
* Microspheres of phospholipids
* Sulfur hexafluoride

* #WHO-EM
* ‡Withdrawn from market
* Clinical trials:
* †Phase III
* §Never to phase III

0.00

(0 votes)

Original source: https://en.wikipedia.org/wiki/Nanoparticle. Read more

|

Retrieved from "https://handwiki.org/wiki/index.php?title=Physics:Nanoparticle&oldid=4368394"
*[v]: View this template
*[t]: Discuss this template
*[e]: Edit this template