Poly(adp-ribose) polymerase family member 14

Short description: Protein-coding gene in the species Homo sapiens

Generic protein structure example

Poly(ADP-ribose) polymerase family member 14 is a protein that, in humans, is encoded by the PARP14 gene. [1]

## Function

Poly(ADP-ribosyl)ation is an immediate DNA damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. PARP14 belongs to the superfamily of enzymes that perform this modification (Ame et al., 2004 [PubMed 15273990]).

## References

1. ↑ "Entrez Gene: Poly(ADP-ribose) polymerase family member 14". https://www.ncbi.nlm.nih.gov/gene/54625. Retrieved 2016-03-02.

## Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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DNA repair

Excision repair|

* Base excision repair/AP site
* DNA glycosylase
* Uracil-DNA glycosylase
* Poly ADP ribose polymerase
* Nucleotide excision repair/ERCC
* XPA
* XPB
* XPC
* XPD/ERCC2
* XPE/DDB1
* XPF/DDB1
* XPG/ERCC5
* ERCC1
* RPA
* RAD23A
* RAD23B
* Excinuclease
* DNA mismatch repair
* MLH1
* MSH2

Other forms of repair|

* Transcription-coupled repair
* ERCC6
* ERCC8
* Homology directed repair
* Non-homologous end joining
* Ku
* Microhomology-mediated end joining
* Postreplication repair
* Photolyase
* CRY1
* CRY2

Other/ungrouped proteins|

* Ogt
* PcrA
* Proliferating Cell Nuclear Antigen
* Homologous recombination
* RecA/RAD51
* Sgs1
* Slx4

Regulation|

* SOS box
* SOS response

Other/ungrouped|

* 8-Oxoguanine
* Adaptive response
* Meiotic recombination checkpoint
* RecF pathway

* DNA helicase: BLM
* WRN

* FANC proteins: core protein complex
* FANCA
* FANCB
* FANCC
* FANCE
* FANCF
* FANCG
* FANCL
* FANCM
* FANCD1
* FANCD2
* FANCI
* FANCJ
* FANCN

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