Thyroid nodule

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In medicine, a thyroid nodule is a "small circumscribed mass in the thyroid gland that can be of neoplastic growth or non-neoplastic abnormality. It lacks a well-defined capsule or glandular architecture. Thyroid nodules are often benign but can be malignant. The growth of nodules can lead to a multinodular goiter (goiter, nodular)."[1] About 5% of thyroid nodules, including incidentalomas, contain thyroid cancer.[2]

A decision analysis of conflicting clinical practice guidelines concluded that selected biopsy of nodules 10-14 mm in size is better than routine biopsies.[3]

## References[edit]

1. ↑ Anonymous (2025), Thyroid nodule (English). Medical Subject Headings. U.S. National Library of Medicine.
2. ↑ Hegedüs L (October 2004). "Clinical practice. The thyroid nodule". N. Engl. J. Med. 351 (17): 1764–71. DOI:10.1056/NEJMcp031436. PMID 15496625. Research Blogging.
3. ↑ McCartney CR, Stukenborg GJ (August 2008). "Decision analysis of discordant thyroid nodule biopsy guideline criteria". J. Clin. Endocrinol. Metab. 93 (8): 3037–44. DOI:10.1210/jc.2008-0448. PMID 18505762. Research Blogging.