Piecemeal necrosis

Short description: Necrosis that occurs in fragments

Sclerotic piecemeal necrosis of the tip of the thumb in a patient with scleroderma.

Piecemeal necrosis generally refers to a necrosis that occurs in fragments.

Piecemeal necrosis in liver aka interface hepatitis is necrosis of the limiting plates, by inflammatory cells. It may be identified as actual necrosis of cells or by irregularity of the limiting plates which is caused IOS's hepatocytes and replacement with inflammatory cells and/or fibrosis.

## Contents

* 1 Liver
* 2 References

## Liver

When used in relation to the [nibbling necrosis[1] and interface necrosis[1]) refers specifically to a loss and degeneration of (limiting plate) hepatocytes at the lobular-portal-interface, producing a moth-eaten irregular appearance.[2] Piecemeal necrosis of the liver is associated with a lymphocytic infiltrate[2] into the adjacent parenchyma,[3] and with destruction of individual hepatocytes along the edges of the portal tract.[3]It is a cardinal feature of chronic viral hepatitis (especially chronic hepatitis) as well as chronic autoimmune hepatitis. > Defined as destruction of hepatocytes at the limiting plate.[citation needed]

## References

1. ↑ 1.0 1.1 Wang, M.; Morgan, T.; Lungo, W.; Wang, L.; Sze, G. Z.; French, S. W. (2001). ""Piecemeal" Necrosis: Renamed Troxis Necrosis". Experimental and Molecular Pathology 71 (2): 137–146. doi:10.1006/exmp.2001.2397. PMID 11599920.
2. ↑ 2.0 2.1 Pathbase > MPATH 597: cell and tissue damage process > MPATH 13: piecemeal necrosis Retrieved July 2, 2011
3. ↑ 3.0 3.1 Transplant Pathology at the University of Pittsburgh > Chronic hepatitis > Chapter 3 > PATHOLOGIC FEATURES Last Modified: Mar 12, 2010

* v
* t
* e

Medicine

Specialties
and
subspecialties|

Surgery

* Cardiac surgery
* Cardiothoracic surgery
* Colorectal surgery
* Eye surgery
* General surgery
* Neurosurgery
* Oral and maxillofacial surgery
* [[[Medicine:Orthopedic surgery|Orthopedic surgery]]
* Hand surgery
* Otolaryngology
* ENT
* Pediatric surgery
* Plastic surgery
* Reproductive surgery
* Surgical oncology
* Thoracic surgery
* Transplant surgery
* Trauma surgery
* Urology
* Andrology
* Vascular surgery

Internal medicine

* Allergy / Immunology
* Angiology
* Cardiology
* Endocrinology
* Gastroenterology
* Hepatology
* Geriatrics
* Hematology
* Hospital medicine|
* Infectious disease
* Nephrology
* Oncology
* Pulmonology
* Rheumatology

Obstetrics and gynaecology

* Gynaecology
* Gynecologic oncology
* Maternal–fetal medicine
* Obstetrics
* Reproductive endocrinology and infertility
* Urogynecology

Diagnostic

* Radiology
* Interventional radiology
* Nuclear medicine
* Pathology
* Anatomical
* Clinical pathology
* Clinical chemistry
* Clinical immunology
* Cytopathology
* Medical microbiology
* Transfusion medicine

Other specialties

* Addiction medicine
* Adolescent medicine
* Anesthesiology
* Dermatology
* Disaster medicine
* Diving medicine
* Emergency medicine
* Mass gathering medicine
* Family medicine
* General practice
* Hospital medicine
* Intensive care medicine
* Medical genetics
* Narcology
* Neurology
* Clinical neurophysiology
* Occupational medicine
* Ophthalmology
* Oral medicine
* Pain management
* Palliative care
* Pediatrics
* Neonatology
* Physical medicine and rehabilitation
* PM&R
* Preventive medicine
* Psychiatry
* Addiction psychiatry
* Radiation oncology
* Reproductive medicine
* Sexual medicine
* Sleep medicine
* Sports medicine
* Transplantation medicine
* Tropical medicine
* Travel medicine
* Venereology

Medical education|

* Medical school
* Bachelor of Medicine, Bachelor of Surgery
* Bachelor of Medical Sciences
* Master of Medicine
* Master of Surgery
* Doctor of Medicine
* Doctor of Osteopathic Medicine
* MD–PhD

Related topics|

* Alternative medicine
* Allied health
* Dentistry
* Podiatry
* Physiotherapy
* Molecular oncology
* Nanomedicine
* Personalized medicine
* Public health
* Traditional medicine
* Veterinary medicine
* Physician
* Chief physician
* History of medicine

* Book
* Category
* Commons
* Wikiproject
* Portal
* Outline

0.00

(0 votes)

|

Retrieved from "https://handwiki.org/wiki/index.php?title=Biology:Piecemeal_necrosis&oldid=4544136"
*[v]: View this template
*[t]: Discuss this template
*[e]: Edit this template