List of IARC Group 2A carcinogens

The agents in this list have been classified in Group 2A (probable carcinogens)[1] by the International Agency for Research on Cancer (IARC). The term "agent" encompasses both substances and exposure circumstances that pose a risk. This designation is applied when there is limited evidence of carcinogenicity in humans as well as sufficient evidence of carcinogenicity in experimental animals. In some cases, an agent may be classified in this group when there is inadequate evidence of carcinogenicity in humans along with sufficient evidence of carcinogenicity in experimental animals and strong evidence that the carcinogenesis is mediated by a mechanism that also operates in humans. Exceptionally, an agent may be classified in this group solely on the basis of limited evidence of carcinogenicity in humans.

## Contents

* 1 Agents
* 1.1 Substances
* 1.2 Mixtures
* 1.3 Exposure circumstances
* 2 References
* 3 External links

## Agents

### Substances

* Acrylamide
* Adriamycin
* Androgenic (anabolic) steroids
* Azacitidine
* BCNU (Bischloroethyl nitrosourea)
* Captafol
* Chloral
* Chloral hydrate
* Chloramphenicol
* α-Chlorinated toluenes (benzal chloride, benzotrichloride, benzyl chloride) and benzoyl chloride (combined exposures)
* CCNU (1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea)
* 4-Chloro-o-toluidine
* Chlorozotocin
* Cisplatin
* Cyclopenta[c,d]pyrene
* Diazinon
* Dibenz[a,j]acridine
* Dibenz[a,h]anthracene
* Dibenzo[a,l]pyrene
* Dichloromethane (methylene chloride)
* Diethyl sulfate
* Dimethylcarbamoyl chloride
* Dimethylformamide
* 1,2-Dimethylhydrazine
* Dimethyl sulfate
* Epichlorohydrin
* Ethylene dibromide
* Ethyl carbamate (urethane)
* N-Ethyl-N-nitrosourea
* Glycidol
* Glyphosate
* Human papillomavirus type 68
* Hydrazine
* Indium phosphide
* 2-Amino-3-methylimidazo[4,5-f]quinoline (IQ)
* Lead compounds, inorganic
* Malaria (caused by infection with Plasmodium falciparum in holoendemic areas)
* Malathion
* 5-Methoxypsoralen
* Methyl methanesulfonate
* Mercaptobenzothiozole
* Merkel cell polyomavirus (MCV)
* MNNG (N-Methyl-N'-nitro-N-nitrosoguanidine)
* N-Methyl-N-nitrosourea
* Nitrate or nitrite (ingested) under conditions that result in endogenous nitrosation
* Nitrogen mustard
* 1-Nitropyrene
* N-Nitrosodiethylamine (DEN)
* N-Nitrosodimethylamine (NDMA)
* Nitrotoluene
* 6-Nitrochrysene
* Phenacetin
* Pioglitazone
* Polybrominated biphenyls
* Procarbazine hydrochloride
* 1,3-Propane sultone
* Styrene-7,8-oxide
* Teniposide
* Tetrabromobisphenol A
* Tetrachloroethylene
* Tetrafluoroethylene
* 1,2,3-Trichloropropane
* Tris(2,3-dibromopropyl) phosphate
* Vinyl bromide
* Vinyl fluoride

### Mixtures

* Bitumens, occasional exposure to oxidized bitumens and their emissions during roofing
* Creosotes (from coal tars)
* High-temperature frying, emissions from
* Household combustion of biomass fuel (primarily wood), indoor emissions from
* Non-arsenical insecticides (occupational exposures in spraying and application of)
* Red meat[2]
* Very hot beverages (more than 65℃)[3]

### Exposure circumstances

* Art glass, glass containers and pressed ware (manufacture of)
* Carbon electrode manufacture
* Cobalt metal with tungsten carbide
* Hairdresser or barber (occupational exposure as a)
* Petroleum refining (occupational exposures in)
* Shift work that involves circadian disruption

## References

1. ↑ "List of Classifications, Volumes 1-115". IARC. February 22, 2016. http://monographs.iarc.fr/ENG/Classification/latest_classif.php.
2. ↑ "IARC Monographs evaluate consumption of red meat and processed meat". http://www.iarc.fr/en/media-centre/pr/2015/pdfs/pr240_E.pdf. Retrieved 26 October 2015.
3. ↑ Loomis, Dana; Guyton, Kathryn Z; Lauby-Sectretan, Béatrice; El Ghissassi, Fatiha; Bouvard, Véronique; Benbrahim-Tallaa, Lamia; Guha, Neela; Mattock, Heidi et al. (2016). "Carcinogenicity of drinking coffee, mate, and very hot beverages". The Lancet Oncology (Elsevier Ltd.) 17: 877–8. June 15, 2016. doi:10.1016/S1470-2045(16)30239-X. PMID 27318851. http://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(16)30239-X/fulltext.

## External links

* Description of the list of classifications, IARC
* List of classifications (latest version)
* List of classifications by cancer site (last updated on 5 November 2015)

* v
* t
* e

Cancer-causing materials and agents (carcinogens)

* Cancer
* Cancer cells

Prominent human carcinogens|

* Acetaldehyde
* Arsenic
* Asbestos
* Bacteria
* Helicobacter Pylori
* Benzo[a]pyrene
* 1,3-Butadiene
* Diethylstilbestrol
* Formaldehyde
* Ionizing radiation (e.g., from isotopes of plutonium and radium)
* Tobacco smoke
* Ultraviolet light
* Viruses
* Epstein–Barr
* Hepatitis B
* Hepatitis C
* Human papillomavirus

IARC lists|

* Group 1
* Group 2A
* Group 2B
* Group 3

* #WHO-EM
* ‡Withdrawn from market
* Clinical trials:
* †Phase III
* §Never to phase III

ja:IARC発がん性リスク一覧

0.00

(0 votes)

|

Retrieved from "https://handwiki.org/wiki/index.php?title=Chemistry:List_of_IARC_Group_2A_carcinogens&oldid=439250"
*[v]: View this template
*[t]: Discuss this template
*[e]: Edit this template