Aromatic-amino-acid—glyoxylate transaminase

aromatic-amino-acid-glyoxylate transaminase

Identifiers
EC number| 2.6.1.60
CAS number| 67185-76-6
Databases
IntEnz| IntEnz view
BRENDA| BRENDA entry
ExPASy| NiceZyme view
KEGG| KEGG entry
MetaCyc| metabolic pathway
PRIAM| profile
PDB structures| RCSB PDB PDBe PDBsum
Gene Ontology| AmiGO  / QuickGO
| Search

PMC| articles
PubMed| articles
NCBI| proteins

In enzymology, an aromatic-amino-acid-glyoxylate transaminase (EC 2.6.1.60) is an enzyme that catalyzes the chemical reaction

an aromatic amino acid + glyoxylate [math]\displaystyle{ \rightleftharpoons }[/math] an aromatic oxo acid + glycine

Thus, the two substrates of this enzyme are aromatic amino acid and glyoxylate, whereas its two products are aromatic oxo acid and glycine.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is aromatic-amino-acid:glyoxylate aminotransferase.

## References

* "Purification and characterization of aromatic-amino-acid-glyoxylate aminotransferase from monkey and rat liver". Hoppe-Seyler's Z. Physiol. Chem. 359 (4): 481-8. 1978. PMID 25837.

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Transferase: nitrogenous groups (EC 2.6)

2.6.1: Transaminases|

* Aspartate transaminase
* GOT1
* GOT2
* Alanine transaminase
* GABA transaminase
* Tyrosine aminotransferase
* Kynurenine—oxoglutarate transaminase
* Ornithine aminotransferase
* Branched-chain amino acid aminotransferase
* Alanine—glyoxylate transaminase
* AGXT

2.6.3: Oximinotransferases|

* Oximinotransferase

2.6.99: Other|

* Pyridoxine 5'-phosphate synthase

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Enzymes

Activity|

* Active site
* Binding site
* Catalytic triad
* Oxyanion hole
* Enzyme promiscuity
* Catalytically perfect enzyme
* Coenzyme
* Cofactor
* Enzyme catalysis

Regulation|

* Allosteric regulation
* Cooperativity
* Enzyme inhibitor
* Enzyme activator

Classification|

* EC number
* Enzyme superfamily
* Enzyme family
* List of enzymes

Kinetics|

* Enzyme kinetics
* Eadie–Hofstee diagram
* Hanes–Woolf plot
* Lineweaver–Burk plot
* Michaelis–Menten kinetics

Types|

* EC1 Oxidoreductases (list)
* EC2 Transferases (list)
* EC3 Hydrolases (list)
* EC4 Lyases (list)
* EC5 Isomerases (list)
* EC6 Ligases (list)
* EC7 Translocases (list)

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Original source: https://en.wikipedia.org/wiki/Aromatic-amino-acid—glyoxylate transaminase. Read more

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