Bertram Fraser-Reid

Born|

Bertram Oliver Fraser-Reid

(1934-02-23)23 February 1934

Coleyville, Jamaica

Died| 25 May 2020(2020-05-25) (aged 86)
Citizenship| Canada and Jamaica
Alma mater| Queen's University, University of Alberta
Known for| Chiral syntheses using carbohydrates, role of oligosaccharides in immune response, “armed-disarmed” principle.
Awards| Merck, Sharp & Dohme Award, Chemical Institute of Canada (1977)
Senior Distinguished US Scientist, Alexander von Humboldt Foundation (1989)
Claude S. Hudson Award in Carbohydrate Chemistry, American Chemical Society (1990)
Jamaican National Foundation Award (1990)
Percy Julian Award, National Organization for the Professional Advancement of Black Chemists and Chemical Engineers (1991)
Haworth Memorial Medal and Lectureship, Royal Society of Chemistry (1995)
Gold Musgrave Medal, Institute of Jamaica (2007)
Scientific career
Fields| Organic chemistry
Institutions| University of Waterloo, University of Maryland, Duke University
Doctoral advisor| Raymond Lemieux

Bertram Oliver "Bert" Fraser-Reid (23 February 1934 – 25 May 2020) was a Jamaican synthetic organic chemist who has been widely recognised for his work using carbohydrates as starting materials for chiral materials and on the role of oligosaccharides in immune response.[1] He developed the “armed-disarmed” principle.[2][3]

## Contents

* 1 Early life
* 2 Academic career
* 3 Achievements
* 4 Other interests
* 5 See also
* 6 References

## Early life

Fraser-Reid was born in Coleyville, Jamaica to William, an elementary school principal, and Laura, a teacher.[4] He had five older siblings.[4] Laura died when Fraser-Reid was only nine months old.[4] He attended Excelsior High School and Clarendon College before moving to Canada to earn BSc (1959) and MSc (1961) at Queen's University in Ontario[4][5] He went to University of Alberta[4] to earn a PhD in 1964[4] under the supervision of Raymond Lemieux. He went to Imperial College London to do postdoctoral work for Nobel Laureate Sir Derek Barton from 1964 to 1966.[4][6]

## Academic career

From 1966 to 1980 Fraser-Reid was on the faculty of the University of Waterloo in Waterloo, Ontario[4] where he established a research group known as "Fraser-Reid's Rowdies".[7] The primary emphasis of his work at this point was the synthesis of chiral natural products using carbohydrates as the starting materials. In 1975, Fraser-Reid was the first to publish a method for making nonsugar compounds with simple sugars.[4] In 1980, he was hired at the University of Maryland, College Park,[4] and then at Duke University in North Carolina in 1983.[4] In 1985 he was appointed the James B. Duke Professor of Chemistry.[4][8] At Duke University, his research shifted to exploring the role of oligosaccharides in immune responses, and particularly on the effect of molecules on human diseases like malaria and AIDS. After retiring from Duke in 1996, due to an undisclosed harassment claim,[9] he established the Natural Products & Glycotechnology Research Institute, a nonprofit, to study the carbohydrate chemistry/biology of tropical parasitic diseases in developing countries and to develop a carbohydrate-based malaria vaccine.[6] Fraser-Reid and his team achieved a milestone in oligosaccharide synthesis by assembling a molecule consisting of 28 monosaccharide units.[10]

## Achievements

Several sources have reported that Fraser-Reid was nominated in 1998 for a Nobel Prize in chemistry for his work on oligosaccharides and immune responses.[7][11][12] This statement cannot be verified since the names of the nominees are never publicly announced, and neither are they told that they have been considered for the Prize. Nomination records are sealed for fifty years.

The Institute of Jamaica awarded Fraser-Reid the 2007 Musgrave Medal (Gold) for his work in chemistry, noting that during his career he co-authored over 330 peer-reviewed publications and supervised 85 post-doctoral fellows and 55 PhD students.[12]

## Other interests

Along with his interest in science, Fraser-Reid was an accomplished pianist and organist who gave recitals at notable venues such as St. George's Cathedral, Kingston, Jamaica (December 1986) and Cathedral de Seville, Spain (August 1995).[12]

In the 1970s Fraser-Reid filed a lawsuit against a building contractor who had not followed municipal building codes. The case went all the way to the Supreme Court of Canada where Fraser-Reid prevailed, and "Fraser-Reid v Droumtsekas" is often cited in Canadian civil law. [13]

## See also

* List of University of Waterloo people

## References

1. ↑ "Bertram Fraser-Reid". The News and Observer & Herald Su. https://www.legacy.com/us/obituaries/heraldsun/name/bertram-fraser-reid-obituary?pid=196325385.
2. ↑ "Bertram Fraser-Reid Obituary (2020)". 2020. https://www.legacy.com/us/obituaries/heraldsun/name/bertram-fraser-reid-obituary?id=8726815.
3. ↑ "Armed/disarmed strategy/effect". 2024. https://chempedia.info/info/armed_disarmed_strategy_effect/.
4. ↑ 4.00 4.01 4.02 4.03 4.04 4.05 4.06 4.07 4.08 4.09 4.10 4.11 Lisa., Yount (1991). Black scientists. New York: Facts on File. ISBN 0816025495. OCLC 22596416.
5. ↑ "Fraser-Reid Biography". Answers.com. http://www.answers.com/topic/bert-fraser-reid.
6. ↑ 6.0 6.1 "The Black Past: Remembered and Reclaimed: Fraser-Reid". BlackPast.org, University of Washington, Seattle. 18 January 2007. http://www.blackpast.org/?q=aah/fraser-reid-bertram-o-1934.
7. ↑ 7.0 7.1 Nelson, Jaevion (20 April 2005). "Panorama: Let Us Honour a Great Man". http://fr.takingitglobal.org/express/panorama/article.html?ContentID=5431.
8. ↑ Fraser-Reid biography. BookRags. http://www.bookrags.com/biography/bertram-oliver-fraser-reid-woc/. Retrieved 20 November 2007.
9. ↑ Dillon, Justin (31 May 1995). "Professor retires amid harassment allegations". The Chronicle Online, The Independent Daily at Duke University. http://www.dukechronicle.com/article/professor-retires-amid-harassment-allegations.
10. ↑ "Largest Synthetic Hetero-Oligosaccharide". Chemical and Engineering News. 8 November 2006. http://pubs.acs.org/cen/news/84/i46/8446carbs.html.
11. ↑ Sheil, Ross (17 January 2007). "The sugar doctor". Jamaica Gleaner. http://www.jamaica-gleaner.com/gleaner/20070117/lead/lead4.html.
12. ↑ 12.0 12.1 12.2 "Musgrave Medal Citation". http://www.instituteofjamaica.org.jm/Docs/citations07/BERT_FRASER_citation.pdf.
13. ↑ "Fraser-Reid v. Droumtsekas". Supreme Court of Canada. https://scc-csc.lexum.com/scc-csc/scc-csc/en/item/4483/index.do.

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