Celine Marmion

Short description: Chemistry researcher

Celine J. Marmion

Alma mater| University of Surrey (PhD)
Kingston University (PGCE)
Scientific career
Institutions| St Mary's University, Twickenham
Royal College of Surgeons in Ireland

Celine J. Marmion is a Professor of Chemistry at the Royal College of Surgeons in Ireland and President of the Institute of Chemistry of Ireland. She is a Fellow of the Royal Society of Chemistry and the Institute of Chemistry of Ireland. Marmion is involved with the design of new chemotherapeutic drugs.

## Contents

* 1 Early life and education
* 2 Research and career
* 2.1 Awards and honours
* 2.2 Selected publications
* 3 References

## Early life and education

Marmion earned her doctoral degree at the University of Surrey in 1994.[1] Her PhD research involved investigations into vanadium complexes and nitrogen fixation. In 1994 Marmion was appointed as a lecturer at St Mary's University, Twickenham, where she worked until 1995.[2] She returned to study in 1995, and earned a Postgraduate Certificate in Education (PGCE) at Kingston University.[3]

## Research and career

In 1997 Marmion joined Royal College of Surgeons in Ireland as a lecturer in the Department of Chemistry.[2] She was promoted to Associate Professor in 2013 and Professor in 2018. Her research considers the design of metal-based chemotherapeutic drugs. In particular, this has included the design of targeted PtIV prodrugs.[4][5] Immunodeficient cancer patients are at risk of developing infections, which occasionally require antimicrobial prophylaxis. To better serve these patients Marmion developed a family of metallo-antibiotics, based on a Cu-N,N-framework, which can bind to DNA, has DNA oxidant properties and has antiproliferative and antimicrobial properties.[6] Her research has been supported by the Science Foundation Ireland (SFI) to create a prodrug strategy for multi-modal chemotherapeutics.[7]

### Awards and honours

Her awards and honours include:

* 2009 Royal College of Surgeons in Ireland President's Teaching Award 'for excellence in teaching'[8]
* 2010 Vice-Dean of the Royal College of Surgeons in Ireland Faculty of Medicine & Health Sciences[8]
* 2013 President of the Irish Biological Inorganic Chemistry Society
* 2013 Elected Fellow of the Royal Society of Chemistry[4]
* 2015 Elected Fellow of the Institute of Chemistry of Ireland[3]
* 2015 Royal College of Surgeons in Ireland President's Teaching Award 'for excellence in teaching'[8]
* 2016 Royal College of Surgeons in Ireland Dean's Academic Award for 'Endeavour, Innovation, Collaboration and Service'[9]
* 2017 Irish Network of Healthcare Educators Education Research Grant[10]
* 2017 Vice President of the Institute of Chemistry of Ireland[11]
* 2019 President of the Institute of Chemistry of Ireland[12]

### Selected publications

Her publications include:

* Marmion, Celine (2019). Metal-based Anticancer Agents. Royal Society of Chemistry. ISBN 9781788014069.
* Marmion, Celine J. (2004). "Hydroxamic Acids− An Intriguing Family of Enzyme Inhibitors and Biomedical Ligands". European Journal of Inorganic Chemistry 2004 (15): 3003–3016. doi:10.1002/ejic.200400221.
* Marmion, Celine J. (2000). "Hydroxamic acids are nitric oxide donors. Facile formation of ruthenium(II)-nitrosyls and NO-mediated activation of guanylate cyclase by hydroxamic acids". Chemical Communications (13): 1153–1154. doi:10.1039/B001631O.

## References

1. ↑ Dublin, T. U.. "TU Dublin News" (in en). https://www.dit.ie/newsandevents/news/archive2017/news/title146043en.html.
2. ↑ 2.0 2.1 "Dr Celine Marmion – Biography". https://www.ucd.ie/cscb/main_pages/research/researchers/marmion_celine/index.html.
3. ↑ 3.0 3.1 "Profile" (in en). https://www.rcsi.com/people/profile/rcostello.
4. ↑ 4.0 4.1 Kenny, Reece G.; Chuah, Su Wen; Crawford, Alanna; Marmion, Celine J. (2017). "Platinum(IV) Prodrugs – A Step Closer to Ehrlich's Vision?" (in en). European Journal of Inorganic Chemistry 2017 (12): 1596–1612. doi:10.1002/ejic.201601278. ISSN 1099-0682.
5. ↑ Kenny, Reece G.; Marmion, Celine J. (2019-01-23). "Toward Multi-Targeted Platinum and Ruthenium Drugs—A New Paradigm in Cancer Drug Treatment Regimens?". Chemical Reviews 119 (2): 1058–1137. doi:10.1021/acs.chemrev.8b00271. ISSN 0009-2665. PMID 30640441.
6. ↑ Ude, Ziga; Kavanagh, Kevin; Twamley, Brendan; Pour, Milan; Gathergood, Nicholas; Kellett, Andrew; Marmion, Celine J. (2019-06-18). "A new class of prophylactic metallo-antibiotic possessing potent anti-cancer and anti-microbial properties" (in en). Dalton Transactions 48 (24): 8578–8593. doi:10.1039/C9DT00250B. ISSN 1477-9234. PMID 30946409.
7. ↑ Harrington, James (2018-10-30). "€3.5m investment in research commercialisation unveiled" (in en-US). http://www.engineersjournal.ie/2018/10/30/e3-5m-investment-research-commercialisation-unveiled/.
8. ↑ 8.0 8.1 8.2 "Speakers – Celebrating Research – Past, Present, Future – Royal College Surgeons in Ireland". https://rcsi.ie/spgsspeakers.
9. ↑ "RCSI Dean's Academic Award". https://www.rcsi.ie/index.jsp?n=110&p=100&a=9083.
10. ↑ inmedlogin. "Past Recipients" (in en-US). https://www.inhed.ie/past-recipients/.
11. ↑ "Annual General Meeting 2017 | Photo gallery | Institute of Chemistry of Ireland". http://www.chemistryireland.org/html/agm2017-photos.html.
12. ↑ "Meet…" (in en-US). 2019-11-06. https://www.euchems.eu/newsletters/chemistry-in-europe-2019-4/meet/.

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