Alpha globulin

Short description: Globular protein in the plasma

Schematic representation of a protein electrophoresis gel

Alpha globulins are a group of globular proteins in plasma[1] that are highly mobile in alkaline or electrically charged solutions. They inhibit certain blood proteases and show significant inhibitor activity.

The alpha globulins typically have molecular weights of around 93 kDa.

## Contents

* 1 Examples
* 1.1 Alpha 1 globulins
* 1.2 Alpha 2 globulins
* 2 References

## Examples

Alpha globulins include certain hormones, proteins that transport hormones, and other compounds, including prothrombin and HDL.

### Alpha 1 globulins

* α1-antitrypsin
* Alpha 1-antichymotrypsin
* Orosomucoid (acid glycoprotein)
* Serum amyloid A
* Alpha 1-lipoprotein
* Protein HC

### Alpha 2 globulins

* Haptoglobin
* Alpha-2u globulin
* α2-macroglobulin
* Ceruloplasmin
* Thyroxine-binding globulin
* Alpha 2-antiplasmin
* Protein C
* Alpha 2-lipoprotein
* Angiotensinogen
* Cortisol binding globulin
* Vitamin D-binding protein

## References

1. ↑ Alpha-Globulins at the US National Library of Medicine Medical Subject Headings (MeSH)

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Proteins: Globular proteins

Serum globulins|

| Alpha globulins|

| serpins:|

* alpha-1 (Alpha 1-antichymotrypsin, Alpha 1-antitrypsin)
* alpha-2 (Alpha 2-antiplasmin)
* Antithrombin (Heparin cofactor II)

|

carrier proteins:|

* alpha-1 (Transcortin)
* alpha-2 (Ceruloplasmin)
* Retinol binding protein

other:|

* alpha-1 (Orosomucoid)
* alpha-2 (alpha-2-Macroglobulin, Haptoglobin)

Beta globulins|

| carrier proteins:|

* Sex hormone-binding globulin
* Transferrin

|

other:|

* Angiostatin
* Hemopexin
* Beta-2 microglobulin
* Factor H
* Plasminogen
* Properdin

Gamma globulin|

* Immunoglobulins

Other|

* Fibronectin (fFN: Fetal fibronectin)
* Macroglobulin/Microglobulin
* Transcobalamin
* Edestin

Other globulins|

* Beta-lactoglobulin
* Lactoferrin
* Thyroglobulin
* Alpha-lactalbumin
* 11S globulin family (seeds)
* 7S globulin family (seeds)

Albumins|

| Egg white|

* Conalbumin
* Ovalbumin
* Avidin

|

Serum albumin|

* Human serum albumin
* Bovine serum albumin
* Prealbumin

Other|

* C-reactive protein
* Lactalbumin (Alpha-lactalbumin)
* Parvalbumin
* Ricin

* see also disorders of globin and globulin proteins

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