Gaze (physiology)

The term gaze is frequently used in physiology to describe coordinated motion of the eyes and neck. The lateral gaze is controlled by the paramedian pontine reticular formation (PPRF).[1] The vertical gaze is controlled by the rostral interstitial nucleus of medial longitudinal fasciculus and the interstitial nucleus of Cajal.[2]

## Contents

* 1 Nerves and muscles
* 2 Conjugate gaze
* 3 References
* 4 External links

## Nerves and muscles

The three nerves that control the extraocular muscles are the oculomotor, trochlear, and abducens nerves, which are the third, fourth, and sixth cranial nerves. the abducens nerve is responsible for abducting the eye, which it controls through contraction of the lateral rectus muscle. The trochlear nerve controls the superior oblique muscle to rotate the eye along its axis in the orbit medially, which is called intorsion, and is a component of focusing the eyes on an object close to the face. The oculomotor nerve controls all the other extraocular muscles, as well as a muscle of the upper eyelid.[3]

## Conjugate gaze

The conjugate gaze is the motion of both eyes in the same direction at the same time, and conjugate gaze palsy refers to an impairment of this function. The conjugate gaze is controlled by four different mechanisms:[4]

* the saccadic system that allows for voluntary direction of the gaze
* the pursuit system that allows the subject to follow a moving object
* nystagmus which includes both vestibular nystagmus and optokinetic nystagmus. The vestibular system restores gaze in compensation for the rotation of the head whereas the optokinetic system restores gaze despite movements of the outside world.
* the vestibulo-ocular reflex system (VOR system) that corrects for the movements of the head to preserve the stable visual image of the world

## References

1. ↑ "Neural Control of Saccadic Eye Movements -- Neuroscience -- NCBI Bookshelf". https://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=neurosci&part=A1360. Retrieved 2009-11-29.
2. ↑ Fukushima, Kikuro (1991). "The interstitial nucleus of Cajal in the midbrain reticular formation and vertical eye movement". Neuroscience Research 10 (3): 159–87. doi:10.1016/0168-0102(91)90055-4. PMID 1650435.
3. ↑ This article incorporates text available under the CC BY 4.0 license.Betts, J Gordon; Desaix, Peter; Johnson, Eddie; Johnson, Jody E; Korol, Oksana; Kruse, Dean; Poe, Brandon; Wise, James et al. (May 14, 2023). Anatomy & Physiology. Houston: OpenStax CNX. 16.3 The Cranial Nerve Exam. ISBN 978-1-947172-04-3. https://openstax.org/books/anatomy-and-physiology/pages/16-3-the-cranial-nerve-exam.
4. ↑ Fowler, Timothy J.; John W. Scadding (2003). Clinical Neurology (3rd ed.). Arnold. ISBN 978-0-340-80798-9.

## External links

* http://www.med.yale.edu/caim/cnerves/cn6/cn6_8.html
* Versino, M; Simonetti, F; Egitto, M G; Ceroni, M; Cosi, V; Versino, M; Ceroni, M; Cosi, V et al. (1999). "Lateral gaze synkinesis on downward saccade attempts with paramedian thalamic and midbrain infarct". Journal of Neurology, Neurosurgery & Psychiatry 67 (5): 696–7. doi:10.1136/jnnp.67.5.696. PMID 10577040.

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