Keratin 13

Short description: Protein-coding gene in the species Homo sapiens

Generic protein structure example

Keratin 13 (or cytokeratin 13) is a protein that in humans is encoded by the KRT13 gene.[1][2]

Keratin 13 is a type I cytokeratin, it is paired with keratin 4 and found in the suprabasal layers of non-cornified stratified epithelia. Mutations in the gene encoding this protein and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus.[3]

## References

1. ↑ "Chromosomal mapping of human cytokeratin 13 gene (KRT13)". Genomics 14 (2): 495–7. October 1992. doi:10.1016/S0888-7543(05)80250-2. PMID 1385306.
2. ↑ "New consensus nomenclature for mammalian keratins". J. Cell Biol. 174 (2): 169–74. July 2006. doi:10.1083/jcb.200603161. PMID 16831889.
3. ↑ "Keratin 13 point mutation underlies the hereditary mucosal epithelial disorder white sponge nevus". Nat. Genet. 11 (4): 453–5. December 1995. doi:10.1038/ng1295-453. PMID 7493031. https://zenodo.org/record/1233409.

## Further reading

* "Expression of cytokeratins 10, 13, 14 and 19 in oral lichen planus". J Oral Sci 51 (3): 355–65. 2009. doi:10.2334/josnusd.51.355. PMID 19776502.
* "Differential Estradiol and Selective Estrogen Receptor Modulator (SERM) Regulation of Keratin 13 Gene Expression and its Underlying Mechanism in Breast Cancer Cells". Mol. Cell. Endocrinol. 296 (1–2): 1–9. 2008. doi:10.1016/j.mce.2008.09.022. PMID 18951949.
* "[Cytokeratin18, 13 and their gene expression in post-operative maxillary cyst linings with metaplastic epithelium]". Zhonghua Kou Qiang Yi Xue Za Zhi 41 (6): 376–9. 2006. PMID 16836912.
* "Human type I cytokeratin genes are a compact cluster". Cytogenet. Cell Genet. 77 (3–4): 169–74. 1997. doi:10.1159/000134566. PMID 9284906.
* "Stage-specific expression of the intermediate filament protein cytokeratin 13 in luminal epithelial cells of secretory phase human endometrium and peri-implantation stage rabbit endometrium". Biol. Reprod. 66 (4): 1006–15. 2002. doi:10.1095/biolreprod66.4.1006. PMID 11906920.
* "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. 1997. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
* "Protein–Protein Interaction Panel Using Mouse Full-Length cDNAs". Genome Res. 11 (10): 1758–65. 2001. doi:10.1101/gr.180101. PMID 11591653.
* "Identification of two novel mutations in keratin 13 as the cause of white sponge naevus". Oral Dis 5 (4): 321–4. 1999. doi:10.1111/j.1601-0825.1999.tb00097.x. PMID 10561721.
* "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell 127 (3): 635–48. 2006. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
* "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
* "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039.
* "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene 138 (1–2): 171–4. 1994. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
* "Constitutional mutation of keratin 13 gene in familial white sponge nevus". Oral Surg Oral Med Oral Pathol Oral Radiol Endod 96 (5): 561–5. 2003. doi:10.1016/s1079-2104(03)00372-x. PMID 14600690.
* "A novel mutation in the keratin 13 gene causing oral white sponge nevus". J. Dent. Res. 80 (3): 919–23. 2001. doi:10.1177/00220345010800031401. PMID 11379896.
* "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2002. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
* "Isolation, sequence and expression of the gene encoding human keratin 13". Gene 215 (2): 269–79. 1998. doi:10.1016/S0378-1119(98)00297-2. PMID 9714826.
* "In situ adenocarcinoma and squamous carcinoma of uterine cervix. Pathological and immunohistochemical analysis with cytokeratin 13". Eur. J. Obstet. Gynecol. Reprod. Biol. 134 (2): 249–53. 2007. doi:10.1016/j.ejogrb.2006.07.047. PMID 16949723.
* "Cable-Piliated Burkholderia cepacia Binds to Cytokeratin 13 of Epithelial Cells". Infect. Immun. 68 (4): 1787–95. 2000. doi:10.1128/IAI.68.4.1787-1795.2000. PMID 10722565.

0.00

(0 votes)

Original source: https://en.wikipedia.org/wiki/Keratin 13. Read more

|

Retrieved from "https://handwiki.org/wiki/index.php?title=Biology:Keratin_13&oldid=2831305"