List of PET radiotracers

This is a list of positron emission tomography (PET) radiotracers. These are chemical compounds in which one or more atoms have been replaced by a short-lived, positron emitting radioisotope.

## Contents

* 1 Cardiology
* 2 Neurology
* 2.1 Neuroepigenetics
* 3 Oncology
* 4 Infectious diseases
* 5 Further reading
* 6 References

## Cardiology

Main page: Engineering:Cardiac PET

* [15O] water
* [13N] ammonia
* [82Rb] Rubidium-82 chloride
* [11C] Acetate (Also used in oncology)

## Neurology

Main page: Biology:Brain positron emission tomography

* [11C] 25B-NBOMe (Cimbi-36)
* [18F] Altanserin
* [11C] Carfentanil
* [11C] DASB
* [11C] DTBZ or [18F]Fluoropropyl-DTBZ
* [11C] [11C] ME@HAPTHI
* [18F] Fallypride
* [18F] Florbetaben
* [18F] Flubatine
* [18F] Fluspidine
* [18F] Florbetapir
* [18F] or [11C] Flumazenil
* [18F] Flutemetamol
* [18F] Fluorodopa
* [18F] Desmethoxyfallypride
* [18F] Mefway
* [18F] MPPF
* [18F] Nifene
* [11C] Pittsburgh compound B
* [11C] Raclopride
* [18F] Setoperone
* [18F] or [11C] N-Methylspiperone
* [11C] Verapamil

NIMH maintains a list of CNS radiotracers that may be useful for additional information.[1]

### Neuroepigenetics

* [11C] Martinostat[2]

## Oncology

* [18F] Fludeoxyglucose (18F) (FDG)-glucose analogue
* [11C] Acetate
* [11C] Methionine
* [11C] choline[3]
* [18F] EF5
* [18F] Fluciclovine[4]
* [18F] Fluorocholine
* [18F] FET
* [18F] FMISO
* [18F] Fluorothymidine F-18
* [64Cu] Cu-ETS2
* [64Cu] Copper-64 DOTA-TATE
* [68Ga] DOTA-pseudopeptides
* [68Ga] DOTA-TATE
* [68Ga] PSMA
* [68Ga] CXCR4; solid and hematologic cancers

## Infectious diseases

* [18F] Fluorodeoxysorbitol (FDS)

## Further reading

CNS Radiotracers that have been advanced for use in Human Studies

## References

1. ↑ "CNS Radiotracer Table". http://www.nimh.nih.gov/research-priorities/therapeutics/cns-radiotracer-table.shtml.
2. ↑ "Insights into neuroepigenetics through human histone deacetylase PET imaging". Science Translational Medicine 8 (351): 351ra106. 10 August 2016. doi:10.1126/scitranslmed.aaf7551. PMID 27510902. "In neurological disorders, HDACs change expression in regions throughout the brain, but their dynamic contribution to human disease development over time is unknown. Wey et al. therefore developed and applied an HDAC imaging probe, called Martinostat, to visualize HDAC expression in the living brain. Martinostat was previously tested in rodents and nonhuman primates, and here, it is used for the first time in humans".
* "Epigenetic Activity Imaged in Human Brain for First Time". Genetic Engineering & Biotechnology News. 11 August 2016. http://www.genengnews.com/gen-news-highlights/epigenetic-activity-imaged-in-human-brain-for-first-time/81253079/.
3. ↑ "Mayo Clinic Gets FDA Approval for New Imaging Agent for Recurrent Prostate Cancer". Mayo Clinic. November 8, 2012. http://www.mayoclinic.org/news2012-rst/7157.html.
4. ↑ FDA approves new diagnostic imaging agent to detect recurrent prostate cancer [1]

* v
* t
* e

Diagnostic radiopharmaceuticals (ATC: V09)

Central nervous system|

* 99mTc (Exametazime)
* 123I (Ioflupane
* Iofetamine
* Iomazenil)
* 18F (Florbetapir, Flutemetamol)

Skeletal system|

* 99mTc (Medronic acid)

Renal|

* 123I (Sodium iodohippurate)
* 64Cu (Cu-ETS2)

Gastrointestinal/Hepatic|

* 75Se (SeHCAT)

Respiratory system|

* 133Xe
* 81mKr
* 99mTc (99mTc-MAA)

Cardiovascular system|

* 99mTc (Sestamibi
* Tetrofosmin)
* 111In (Imciromab)
* 82Rb (Rubidium chloride)

Inflammation/infection|

* 99mTc (Exametazime
* Sulesomab
* Tilmanocept)
* 111In
* 67Ga

Tumor|

* 99mTc (Arcitumomab
* Votumumab
* Hynic-octreotide)
* 111In (Capromab pendetide
* Satumomab pendetide)
* 125I (Minretumomab)
* 123I / 131I (Iobenguane)
* 18F (Fluciclovine
* Fludeoxyglucose
* Fluoroethyltyrosine
* Sodium fluoride)

Adrenal cortex|

* 123I
* 125I / 131I (Iodocholesterol)

Radionuclides
(including tracers)|

| positron (PET list)|

* 11C ([11C]ME@HAPTHI
* 25B-NBOMe (Cimbi-36)
* Acetate
* Choline
* Carfentanil
* DASB
* DTBZ
* Flumazenil
* Methionine
* N-Methylspiperone
* Pittsburgh compound B
* Raclopride
* Verapamil)
* 13N (Ammonia)
* 15O (Water)
* 18F (Altanserin
* Desmethoxyfallypride
* FMISO
* Fallypride
* Florbetaben
* Florbetapir
* Flubatine
* Fluciclovine
* Fludeoxyglucose (18F) (FDG)-glucose analogue
* Flumazenil
* Fluorocholine
* Fluorodeoxysorbitol (FDS)
* Fluorodopa
* Fluorothymidine F-18
* Fluspidine
* Flutemetamol
* MPPF
* Mefway
* Nifene
* N-Methylspiperone
* FET
* Setoperone)
* 64Cu
* 68Ga
* 82Rb (Rubidium chloride)

|

gamma ray/photon (SPECT/scintigraphy)|

* 51Cr
* 57Co
* 67Ga
* 75Se
* 81mKr
* 99mTc
* 111In
* 123I
* 125I
* 131I
* 133Xe
* 153Sm
* 201Tl

0.00

(0 votes)

Original source: https://en.wikipedia.org/wiki/List of PET radiotracers. Read more

|

Retrieved from "https://handwiki.org/wiki/index.php?title=Biology:List_of_PET_radiotracers&oldid=3595287"
*[v]: View this template
*[t]: Discuss this template
*[e]: Edit this template