4-(4-Methylphenyl)-4-oxobutanoic acid

Names
Preferred IUPAC name

4-(4-Methylphenyl)-4-oxobutanoic acid

Other names

3-(4-Methylbenzoyl)propionic acid
3-(p-Toluoyl)propionic acid
4-(4-Methylphenyl)-4-oxobutyric acid

Identifiers

CAS Number

* 4619-20-9 Y

3D model (JSmol)

* Interactive image

ChemSpider |

* 213498 Y

EC Number |

* 610-285-9

PubChem CID

* 244162

UNII |

* ZYB7JU7CMX

InChI

* InChI=1S/C11H12O3/c1-8-2-4-9(5-3-8)10(12)6-7-11(13)14/h2-5H,6-7H2,1H3,(H,13,14) Y

Key: OEEUWZITKKSXAZ-UHFFFAOYSA-N Y

* InChI=1/C11H12O3/c1-8-2-4-9(5-3-8)10(12)6-7-11(13)14/h2-5H,6-7H2,1H3,(H,13,14)

Key: OEEUWZITKKSXAZ-UHFFFAOYAH

SMILES

* O=C(c1ccc(cc1)C)CCC(=O)O

Properties

Chemical formula

| C11H12O3
Molar mass | 192.214 g·mol−1
Appearance  | White powder
Melting point |  129 °C (264 °F; 402 K)

Solubility in water

| Insoluble
Hazards[1]
Main hazards | Flammable
GHS pictograms |
GHS Signal word | Warning

GHS hazard statements

| H315, H319, H335

GHS precautionary statements

| P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P332+313, P337+313, P362, P403+233, P405, P501

Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

N verify (what is YN ?)
Infobox references

4-(4-Methylphenyl)-4-oxobutanoic acid is an organic carboxylic acid. The preparation of it is used for undergraduate teaching of organic chemistry synthesis.

## Preparation

4-(4-Methylphenyl)-4-oxobutanoic acid can be prepared by a Friedel–Crafts reaction between toluene and succinic anhydride catalyzed by a Lewis acid such as aluminium chloride.[2]

## References

1. ↑ "3-(4-Methylbenzoyl)propionic acid" (in en). https://pubchem.ncbi.nlm.nih.gov/compound/244162#section=Safety-and-Hazards.
2. ↑ Preparation of 4-(p-methylphenyl)-4-oxobutanoic acid, Li Cuijuan, Lv Mingquan, Han Shuying, Xu Tanfeng (College of Chemistry and Molecule Engineering, Peking University), College Chemistry, Vol 20. Period 2.

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*[CID]: Compound ID
*[H315]: Causes skin irritation
*[H319]: Causes serious eye irritation
*[H335]: May cause respiratory irritation
*[P261]: Avoid breathing dust/fume/gas/mist/vapours/spray
*[P264]: Wash … thoroughly after handling
*[P271]: Use only outdoors or in a well-ventilated area
*[P280]: Wear protective gloves/protective clothing/eye protection/face protection
*[P302+352]: IF ON SKIN: Wash with soap and water
*[P304+340]: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
*[P305+351+338]: IF IN EYES: Rinse continuously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing
*[P312]: Call a POISON CENTER or doctor/physician if you feel unwell
*[P332+313]: If skin irritation occurs: Get medical advice/attention
*[P337+313]: Get medical advice/attention
*[P362]: Take off contaminated clothing and wash before reuse
*[P403+233]: Store in a well ventilated place. Keep container tightly closed
*[P405]: Store locked up
*[P501]: Dispose of contents/container to …