Almagate

Short description: Chemical compound

AlmagateClinical data

AHFS/Drugs.com| International Drug Names
Routes of
administration| Oral
ATC code|

* A02AD03 (WHO)

Identifiers
CAS Number|

* 66827-12-1

PubChem CID|

* 71749

ChemSpider|

* 64792 Y

UNII|

* 568Z59H7ZJ

KEGG|

* D02821 Y

Chemical and physical data
Formula| Al2Mg6(OH)14(CO3)2 · 4 H2O
Molar mass| 314.99 g/mol
3D model (JSmol)|

* Interactive image

SMILES

* [Al+3].[Mg+2].[Mg+2].[Mg+2].[OH-].[OH-].[OH-].[O-]C([O-])=O.[OH-].[OH-].[OH-].[OH-].O.O

InChI

* InChI=1S/CH2O3.Al.3Mg.9H2O/c2-1(3)4;;;;;;;;;;;;;/h(H2,2,3,4);;;;;9*1H2/q;+3;3*+2;;;;;;;;;/p-9 Y

* Key:MTEOMEWVDVPTNN-UHFFFAOYSA-E Y

(verify)

Almagate (trade name Almax) is an aluminium\- and magnesium-containing antacid. It was first described in 1984.[1][2]

## Adverse effects

Almagate is well tolerated. In a clinical trial, the most common adverse effects were diarrhea and nausea.[3]

## References

1. ↑ "Characterization of a new crystalline synthetic gastric antacid, almagate" (Free full text). Arzneimittel-Forschung 34 (10A): 1346–9. 1984. PMID 6548918. http://toxnet.nlm.nih.gov/cgi-bin/sis/search/r?dbs+hsdb:@term+@rn+21645-51-2.
2. ↑ "Evaluation of a new antacid, almagate" (Free full text). Arzneimittel-Forschung 34 (10A): 1350–4. 1984. PMID 6439224. http://toxnet.nlm.nih.gov/cgi-bin/sis/search/r?dbs+hsdb:@term+@rn+21645-51-2.
3. ↑ "Treatment of gastric pyrosis with almagate in patients with and without endoscopically demonstrable duodenal ulcer. A multicentre clinical trial" (Free full text). Arzneimittel-Forschung 34 (10A): 1380–3. 1984. PMID 6548926. http://toxnet.nlm.nih.gov/cgi-bin/sis/search/r?dbs+hsdb:@term+@rn+21645-51-2.

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Drugs for acid related disorders: Antacids (A02A)

Magnesium (increases motility)|

* Magnesium carbonate
* Magnesium oxide
* Magnesium peroxide
* Magnesium hydroxide
* Magnesium silicate

Aluminium (decreases motility)|

* Aceglutamide aluminum
* Algeldrate
* Aluminium phosphate
* Aluminium acetoacetate
* Aloglutamol
* Aluminium glycinate
* Carbaldrate

Calcium|

* Calcium carbonate
* Calcium silicate

Sodium|

* Sodium bicarbonate

Combinations and complexes
of aluminium, calcium and magnesium|

* Almagate
* Almasilate
* Hydrotalcite
* Magaldrate

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