Ciclobendazole

Short description: Chemical compound

Ciclobendazole

Clinical data
ATC code|

* P02CA04 (WHO)

Identifiers

IUPAC name

* Methyl N-[6-(cyclopropanecarbonyl)-1H-benzimidazol-2-yl]carbamate

CAS Number|

* 31431-43-3 Y

PubChem CID|

* 35803

ChemSpider|

* 32933 N

UNII|

* JF3KQ40J31

KEGG|

* D03623 Y

Chemical and physical data
Formula| C13H13N3O3
Molar mass| 259.265 g·mol−1
3D model (JSmol)|

* Interactive image

SMILES

* COC(=O)Nc3nc2ccc(C(=O)C1CC1)cc2[nH]3

InChI

* InChI=1S/C13H13N3O3/c1-19-13(18)16-12-14-9-5-4-8(6-10(9)15-12)11(17)7-2-3-7/h4-7H,2-3H2,1H3,(H2,14,15,16,18) N

* Key:OXLKOMYHDYVIDM-UHFFFAOYSA-N N

NY (what is this?) (verify)

Ciclobendazole is an anthelmintic, that is a pharmaceutical drug against parasitic worms. It underwent a clinical trial in the 1970s, where it was found to be as effective as mebendazole in the treatment of hookworm infection and ascariasis, but significantly less effective in the treatment of trichuriasis.[1]

It is not known to be marketed anywhere in the world.[2]

## References

1. ↑ "Comparative trial on the therapeutic effectiveness of the new anthelmintic drug: ciclobendazole". Tropenmedizin und Parasitologie 29 (4): 423–6. December 1978. PMID 369076.
2. ↑ "Ciclobendazole search results". Drugs.com. https://www.drugs.com/search.php?searchterm=ciclobendazole. Retrieved 2021-03-31.

* v
* t
* e

Antiparasitics – Anthelmintics (P02) and Endectocides (QP54)

Antiplatyhelmintic agents|

| Antitrematodals
(schistosomicides)|

| Binds tubulin|

* benzimidazole
* Triclabendazole#

|

AI|

* phosphonic acid
* Metrifonate‡

Other/unknown|

* quinoline
* Praziquantel#
* Oxamniquine#
* phenol
* Bithionol
* thiazole
* Niridazole
* arylsulfonate
* Stibophen

Anticestodals
(taeniacides)|

| Binds tubulin|

* benzimidazole
* Albendazole#

|

Other/unknown|

* quinoline
* Praziquantel#
* salicylanilide
* Niclosamide#
* aminoacridine
* Quinacrine
* butyrophenone
* Desaspidin
* chlorophenol
* Dichlorophen

Antinematodal agents
(including
macrofilaricides)|

| Binds tubulin|

* benzimidazole
* Mebendazole#
* Albendazole#
* Tiabendazole
* Fenbendazole
* Ciclobendazole
* Flubendazole

|

Glutamate-gated chloride channel, GABA receptor|

* avermectins
* Abamectin
* Doramectin
* Emamectin
* Ivermectin#
* Selamectin
* milbemycins
* Moxidectin
* Milbemycin oxime

NMDA|

* tetrahydropyrimidine
* Pyrantel#
* pyrantel pamoate
* Oxantel
* Morantel
* Carbantel
* Febantel (aka felsantel)

Other/unknown|

* piperazine
* Piperazine
* Diethylcarbamazine#
* thiazole
* Levamisole#
* quinolinium
* Pyrvinium
* benzylammonium
* Bephenium
* naphthalenesulfonate
* Suramin#
* Tribendimidine

* #WHO-EM
* ‡Withdrawn from market
* Clinical trials:
* †Phase III
* §Never to phase III

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