EDANS

Names
Preferred IUPAC name

5-[(2-Aminoethyl)amino]naphthalene-1-sulfonic acid

Other names

EDANS

Identifiers

CAS Number

* 50402-56-7 Y

3D model (JSmol)

* Interactive image

ChemSpider |

* 83355 N

PubChem CID

* 92329

UNII |

* 3JBY896YZF Y

InChI

* InChI=1S/C12H14N2O3S/c13-7-8-14-11-5-1-4-10-9(11)3-2-6-12(10)18(15,16)17/h1-6,14H,7-8,13H2,(H,15,16,17) N

Key: SJQRQOKXQKVJGJ-UHFFFAOYSA-N N

* InChI=1/C12H14N2O3S/c13-7-8-14-11-5-1-4-10-9(11)3-2-6-12(10)18(15,16)17/h1-6,14H,7-8,13H2,(H,15,16,17)

Key: SJQRQOKXQKVJGJ-UHFFFAOYAN

SMILES

* c1cc2c(cccc2S(=O)(=O)O)c(c1)NCCN

Properties

Chemical formula

| C12H14N2O3S
Molar mass | 266.32

Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

N verify (what is YN ?)
Infobox references

EDANS (5-((2-Aminoethyl)amino)naphthalene-1-sulfonic acid) is a donor for FRET-based nucleic acid probes and protease substrates. EDANS is often paired with DABCYL or DABSYL. The combination can be used in enzyme assays. When the two compounds are in close proximity, most of the energy emitted from EDANS will be quenched by DABCYL. However, if the compounds are separated (for example, by substrate cleavage) EDANS will fluoresce, giving an indication of enzyme presence.[1]

## See also

* Dark quencher

## References

1. ↑ Guo, Jiubiao (30 November 2014). "Spectral properties of EDANS-Dabcyl pair [45 and the flowchart of the experimental design."]. PLOS ONE 9 (12). doi:10.1371/journal.pone.0114124.g001. https://figshare.com/articles/_Spectral_properties_of_EDANS_Dabcyl_pair_45_and_the_flowchart_of_the_experimental_design_/1255607.

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*[CID]: Compound ID