Harmol

Names
IUPAC name

1-Methyl-2,9-dihydropyrido[3,4-b]indol-7-one

Identifiers

CAS Number

* 487-03-6 Y

3D model (JSmol)

* Interactive image

ChEBI |

* CHEBI:192558

ChemSpider |

* 10296888

PubChem CID

* 68094

UNII |

* 7PQ075MCA6 Y

SMILES

* CC1=C2C(=C3C=CC(=O)C=C3N2)C=CN1

Properties

Chemical formula

| C12H10N2O
Molar mass | 198.225 g·mol−1

Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Infobox references

Tracking categories (test):

* SizeSet

Harmol is a chemical compound classified as a β-carboline.[1][2][3] It is readily formed in vivo in humans by O-demethylation of harmine.[4]

## See also

* Harmalol

## References

1. ↑ "Harmol induces autophagy and subsequent apoptosis in U251MG human glioma cells through the downregulation of survivin". Oncol Rep 29 (4): 1333–42. 2013. doi:10.3892/or.2013.2242. PMID 23338618.
2. ↑ "Transcriptional and posttranslational inhibition of dioxin-mediated induction of CYP1A1 by harmine and harmol". Toxicol Lett 208 (1): 51–61. 2012. doi:10.1016/j.toxlet.2011.09.030. PMID 22001777.
3. ↑ "The β-carboline alkaloid harmol induces cell death via autophagy but not apoptosis in human non-small cell lung cancer A549 cells.". Biol Pharm Bull 34 (8): 1264–72. 2011. doi:10.1248/bpb.34.1264. PMID 21804216.
4. ↑ "The alkaloids of Banisteriopsis caapi, the plant source of the Amazonian hallucinogen Ayahuasca, stimulate adult neurogenesis in vitro". Sci. Rep. 7 (1): 5309. 2017. doi:10.1038/s41598-017-05407-9. PMID 28706205. Bibcode: 2017NatSR...7.5309M.

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*[CID]: Compound ID