Isopropyl myristate

Isopropyl myristate[1]

Names
Preferred IUPAC name

Propan-2-yl tetradecanoate

Other names

Tetradecanoic acid, 1-methylethyl ester
Myristic acid isopropyl ester

Identifiers

CAS Number

* 110-27-0 Y

3D model (JSmol)

* Interactive image

ChEMBL |

* ChEMBL207602

ChemSpider |

* 7751 Y

EC Number |

* 203-751-4

KEGG |

* D02296 Y

MeSH | C008205

PubChem CID

* 8042

RTECS number |

* XB8600000

UNII |

* 0RE8K4LNJS Y

InChI

* InChI=1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3 N

Key: AXISYYRBXTVTFY-UHFFFAOYSA-N N

* InChI=1/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3

Key: AXISYYRBXTVTFY-UHFFFAOYAN

SMILES

* CCCCCCCCCCCCCC(=O)OC(C)C

Properties

Chemical formula

| C17H34O2
Molar mass | 270.457 g·mol−1
Density | 0.85 g/cm3
Boiling point |  167 °C (333 °F; 440 K) at 9 mmHg
Hazards
NFPA 704 (fire diamond)  |

Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

N verify (what is YN ?)
Infobox references

Tracking categories (test):

* SizeSet

Isopropyl myristate (IPM) is the ester of isopropyl alcohol and myristic acid.

## Uses

Isopropyl myristate is a polar emollient and is used in cosmetic and topical pharmaceutical preparations where skin absorption is desired. It is also used as a treatment for head lice.[2] It is also in flea and tick killing products for pets.

It is used to remove bacteria from the oral cavity as the non-aqueous component of the two-phase mouthwash product "Dentyl pH".

Isopropyl myristate is also used as a solvent in perfume materials, and in the removal process of prosthetic make-up.

Hydrolysis of the ester from isopropyl myristate can liberate the acid and the alcohol. The acid is theorized to be responsible for decreasing of the pH value of formulations.[3][4]

## References

1. ↑ MSDS for isopropyl myristate
2. ↑ Anti-Lice Treatments
3. ↑ Wen, Z.; Fang, L. and He, Z. (2009). Effect of chemical enhancers on percutaneous absorption of daphnetin in isopropyl myristate vehicle across rat skin in vitro. Drug Deliv, 16: 214-223
4. ↑ Engelbrecht, T.; Demé, B.; Dobner, B. and Neubert, R. (2012). Study of the influence of the penetration enhancer isopropyl myristate on the nanostructure of stratum corneum lipid model membranes using neutron diffraction and deuterium labelling. Skin Pharmacol Physiol, 25:200-7

## External links

* Isopropyl myristate in the Consumer Product Information Database

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*[CID]: Compound ID