JXL082

JXL082, or JXL-082, is a drug acting as a mitochondrial pyruvate carrier (MPC) inhibitor which was synthesized towards the aim of developing a treatment for hair loss.[1][2] It is related to other drugs in the same series such as PP405, JXL069, and UK-5099 (JXL001).[1][2] The drug is known to have been sold online in a grey market fashion for treatment of hair loss.[2] It has been mistakenly believed to be PP405, but PP405 is said not to be JXL082.[2] JXL082 was first described in the scientific literature by 2019.[3][1]

## See also

* List of investigational hair loss drugs
* JXL069
* PP405
* UK-5099 (JXL001)

## References

1. ↑ 1.0 1.1 1.2 "Development of Novel Mitochondrial Pyruvate Carrier Inhibitors to Treat Hair Loss". Journal of Medicinal Chemistry 64 (4): 2046–2063. February 2021. doi:10.1021/acs.jmedchem.0c01570. PMID 33534563.
2. ↑ 2.0 2.1 2.2 2.3 "The Great Unbalding Draws Nearer". 12 August 2025. https://nymag.com/intelligencer/article/pp405-baldness-cure-hair-loss-treatment-follicles-science-tressless.html.
3. ↑ Lowry WE, Jung ME, Christofk H, Liu X, "Compositions and methods for modulating hair growth", WO patent 2019006359A1, published 3 January 2019, assigned to University of California Berkeleyand University of California San Diego UCSD

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