Jedi1

Names
Preferred IUPAC name

2-methyl-5-phenylfuran-3-carboxylic acid

Identifiers

CAS Number

* 108124-17-0 Y

3D model (JSmol)

* Interactive image

PubChem CID

* 736516

InChI

* InChI=1S/C12H10O3/c1-8-10(12(13)14)7-11(15-8)9-5-3-2-4-6-9/h2-7H,1H3,(H,13,14)

Key: VLMNACSEESRUAK-UHFFFAOYSA-N

SMILES

* CC1=C(C=C(O1)C2=CC=CC=C2)C(=O)O

Properties

Chemical formula

| C12H10O3
Molar mass | 202.209 g·mol−1

Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Infobox references

Jedi1 (IUPAC name: 2-methyl-5-phenylfuran-3-carboxylic acid) is a chemical compound which acts as an agonist for the mechanosensitive ion channel PIEZO1, and is used in research into the function of touch perception.[1][2]

## See also

* Yoda1 and Jedi2

## References

1. ↑ "A lever-like transduction pathway for long-distance chemical- and mechano-gating of the mechanosensitive Piezo1 channel". Nature Communications 9 (1): 1300. April 2018. doi:10.1038/s41467-018-03570-9. PMID 29610524. Bibcode: 2018NatCo...9.1300W.
2. ↑ "Structure, kinetic properties and biological function of mechanosensitive Piezo channels". Cell & Bioscience 11 (1): 13. January 2021. doi:10.1186/s13578-020-00522-z. PMID 33422128.

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*[CID]: Compound ID