MOPS

Names
Preferred IUPAC name

3-(Morpholin-4-yl)propane-1-sulfonic acid

Other names

3-(N-Morpholino)propanesulfonic acid,
3-Morpholinopropanesulfonic acid,
3-N-Morpholino propansulfonic acid,
4-Morpholinepropanesulfonic acid

Identifiers

CAS Number

* 1132-61-2 Y

3D model (JSmol)

* Interactive image

ChemSpider |

* 63972 N

PubChem CID

* 70807
* 2723950

UNII |

* 273BP63NV3 Y

InChI

* InChI=1S/C7H15NO4S/c9-13(10,11)7-1-2-8-3-5-12-6-4-8/h1-7H2,(H,9,10,11) N

Key: DVLFYONBTKHTER-UHFFFAOYSA-N N

* InChI=1/C7H15NO4S/c9-13(10,11)7-1-2-8-3-5-12-6-4-8/h1-7H2,(H,9,10,11)

Key: DVLFYONBTKHTER-UHFFFAOYAN

SMILES

* C1COCCN1CCCS(=O)(=O)O

Properties

Chemical formula

| C7H15NO4S
Molar mass | 209.26 g·mol−1
Hazards
Safety data sheet | MSDS
GHS pictograms |
GHS Signal word | Warning

GHS hazard statements

| H315, H319, H335

GHS precautionary statements

| P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362, P403+233, P405, P501

Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

N verify (what is YN ?)
Infobox references

MOPS (3-(N-morpholino)propanesulfonic acid) is a buffer introduced in the 1960s, one of the twenty Good's buffers. It is a structural analog to MES,[1] and like MES, its structure contains a morpholine ring. HEPES is a similar pH buffering compound that contains a piperazine ring. With a pKa of 7.20, MOPS is an excellent buffer for many biological systems at near-neutral pH.

## Contents

* 1 Applications
* 2 See also
* 3 References
* 4 External links

## Applications

MOPS is frequently used as a buffering agent in biology and biochemistry. It has been tested and recommended for polyacrylamide gel electrophoresis.[2] Usage above 20 mM in mammalian cell culture work is not recommended.[3] MOPS buffer solutions become discolored (yellow) over time, but reportedly slight discoloration does not significantly affect the buffering characteristics.[4]

## See also

* CAPS
* HEPPS
* Tris
* Common buffer compounds used in biology

## References

1. ↑ Good, Norman E.; Winget, G. Douglas; Winter, Wilhelmina; Connolly, Thomas N.; Izawa, Seikichi; Singh, Raizada M. M. (1966). "Hydrogen Ion Buffers for Biological Research". Biochemistry 5 (2): 467–77. doi:10.1021/bi00866a011. PMID 5942950.
2. ↑ Thomas, J; Hodes, ME (1981). "A new discontinuous buffer system for the electrophoresis of cationic proteins at near-neutral pH". Analytical Biochemistry 118 (1): 194–6. doi:10.1016/0003-2697(81)90178-0. PMID 6278979.
3. ↑ Eagle, H. (1971). "Buffer Combinations for Mammalian Cell Culture". Science 174 (4008): 500–3. doi:10.1126/science.174.4008.500. PMID 5110427. Bibcode: 1971Sci...174..500E.
4. ↑ "Error: no `|title=` specified when using {{Cite web}}". https://bostonbioproducts.com/products/mops-buffer-1-m-ph-74-bbm-74.Error:+no+`|title=`+specified when+using+{{[[Template:Cite+web|Cite+web]]}}&rft.atitle=&rft_id=https://bostonbioproducts.com/products/mops-buffer-1-m-ph-74-bbm-74&rfr_id=info:sid/en.wikibooks.org:Chemistry:MOPS">

## External links

* Sigma Aldrich Buffer Calculator \- Useful tool to calculate weight, volume, or concentration from molecular weight.
* Recipe for MOPS buffer on OpenWetWare

0.00

(0 votes)

Original source: https://en.wikipedia.org/wiki/MOPS. Read more

|

Retrieved from "https://handwiki.org/wiki/index.php?title=Chemistry:MOPS&oldid=823694"
*[CID]: Compound ID
*[H315]: Causes skin irritation
*[H319]: Causes serious eye irritation
*[H335]: May cause respiratory irritation
*[P261]: Avoid breathing dust/fume/gas/mist/vapours/spray
*[P264]: Wash … thoroughly after handling
*[P271]: Use only outdoors or in a well-ventilated area
*[P280]: Wear protective gloves/protective clothing/eye protection/face protection
*[P302+352]: IF ON SKIN: Wash with soap and water
*[P304+340]: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
*[P305+351+338]: IF IN EYES: Rinse continuously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing
*[P312]: Call a POISON CENTER or doctor/physician if you feel unwell
*[P321]: Specific treatment (see … on this label)
*[P332+313]: If skin irritation occurs: Get medical advice/attention
*[P337+313]: Get medical advice/attention
*[P362]: Take off contaminated clothing and wash before reuse
*[P403+233]: Store in a well ventilated place. Keep container tightly closed
*[P405]: Store locked up
*[P501]: Dispose of contents/container to …