Seychelles Child Development Study

The Seychelles Child Development Study is a project created in 1986 by the Ministries of Health and Education in Seychelles, in cooperation with the University of Rochester and the University of Ulster. Its goal is to monitor the effects of mercury exposure (primarily low-level exposure from fish consumption) on infants and young children, especially with regard to neurodevelopmental disorders.[1] In the study, hair mercury levels are used as the index of exposure.[2] A number of scientific studies have been produced as a result of this project, which have generally concluded that there is no evidence that methylmercury consumption results in an increased risk of neurodevelopmental disorders,[3][4][5][6][7][8][9] though one article did note that "the association with activity suggests the need for further study of this cohort."[2] In 2011, a joint FAO/World Health Organization committee published a report, which, based on the SCDS, concluded that the health benefits associated with the omega-3 fatty acids in fish outweighed the potential adverse neurological effects of mercury intake from fish.[10]

## References

1. ↑ "Seychelles Child Development Study". University of Rochester. http://www.urmc.rochester.edu/pediatrics/research/Seychelles-Child-Development-Study.aspx.
2. ↑ 2.0 2.1 Myers, G. J.; Davidson, P. W.; Cox, C.; Shamlaye, C. F.; Choisy, O.; Cernichiari, E.; Choi, A.; Sloane-Reeves, J. et al. (1997). "The seychelles child development study: Results and new directions through twenty-nine months". Water, Air, & Soil Pollution 97 (1–2): 53–61. doi:10.1007/BF02409644. Bibcode: 1997WASP...97...53M.
3. ↑ Myers, G. J.; Davidson, P. W.; Cox, C.; Shamlaye, C. F.; Palumbo, D.; Cernichiari, E.; Sloane-Reeves, J.; Wilding, G. E. et al. (2003). "Prenatal methylmercury exposure from ocean fish consumption in the Seychelles child development study". The Lancet 361 (9370): 1686–1692. doi:10.1016/S0140-6736(03)13371-5. PMID 12767734.
4. ↑ Myers, G. J.; Davidson, P. W.; Shamlaye, C. F.; Axtell, C. D.; Cernichiari, E.; Choisy, O.; Choi, A.; Cox, C. et al. (1997). "Effects of prenatal methylmercury exposure from a high fish diet on developmental milestones in the Seychelles Child Development Study". Neurotoxicology 18 (3): 819–829. PMID 9339828.
5. ↑ Crump, K. S.; Van Landingham, C.; Shamlaye, C.; Cox, C.; Davidson, P. W.; Myers, G. J.; Clarkson, T. W. (2000). "Benchmark concentrations for methylmercury obtained from the Seychelles Child Development Study". Environmental Health Perspectives 108 (3): 257–263. doi:10.1289/ehp.00108257. PMID 10706533.
6. ↑ Van Wijngaarden, E. (2013). "Prenatal methyl mercury exposure in relation to neurodevelopment and behavior at 19 years of age in the Seychelles Child Development Study". Neurotoxicology and Teratology 39: 19–25. doi:10.1016/j.ntt.2013.06.003. PMID 23770126.
7. ↑ Davidson, P. W.; Leste, A.; Benstrong, E.; Burns, C. M.; Valentin, J.; Sloane-Reeves, J.; Huang, L. S.; Miller, W. A. et al. (2010). "Fish consumption, mercury exposure, and their associations with scholastic achievement in the Seychelles Child Development Study☆". NeuroToxicology 31 (5): 439–447. doi:10.1016/j.neuro.2010.05.010. PMID 20576509.
8. ↑ Van Wijngaarden, E.; Davidson, P. W.; Smith, T. H.; Evans, K.; Yost, K.; Love, T.; Thurston, S. W.; Watson, G. E. et al. (2013). "Autism Spectrum Disorder Phenotypes and Prenatal Exposure to Methylmercury". Epidemiology 24 (5): 651–659. doi:10.1097/EDE.0b013e31829d2651. PMID 23873071.
9. ↑ Willingham, Emily (24 July 2013). "Mercury and autism not linked, again". Forbes.com. https://www.forbes.com/sites/emilywillingham/2013/07/24/mercury-and-autism-not-linked-again/.
10. ↑ "Seychelles". University of Ulster. http://www.ulster.ac.uk/annualreview/2011/international/places/seychelles.php.

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