Tricarboxylic acid

Short description: Organic carboxylic acid

A tricarboxylic acid is an organic carboxylic acid whose chemical structure contains three carboxyl functional groups (-COOH). The best-known example of a tricarboxylic acid is citric acid.

## Contents

* 1 Uses
* 1.1 Citric acid cycle
* 2 Examples
* 3 See also
* 4 Literature

## Uses

### Citric acid cycle

Main article: Biology:Citric acid cycle

Citric acid, a type of tricarboxylic acid, is used in the citric acid cycle – also known as tricarboxylic acid (TCA) cycle or Krebs cycle – which is fundamental to all aerobic organisms.

## Examples

Common name | IUPAC name | Molecular formula | Structural formula

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|
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Citric acid | 2-hydroxypropane-1,2,3-tricarboxylic acid | C6H8O7 |
Isocitric acid | 1-hydroxypropane-1,2,3-tricarboxylic acid | C6H8O7 |
Aconitic acid | Prop-1-ene-1,2,3-tricarboxylic acid | C6H6O6 |

(cis-form & trans-form)

Propane-1,2,3-tricarboxylic acid | Propane-1,2,3-tricarboxylic acid | C3H5(COOH)3 |
Agaric acid | 2-Hydroxynonadecane-1,2,3-tricarboxylic acid  | C22H40O7 |
Trimesic acid | benzene-1,3,5-tricarboxylic acid | C9H6O6 |

## See also

* Citric acid cycle (tricarboxylic acid cycle)
* Dicarboxylic acid
* Mellitic acid

## Literature

* Ryan J. Mailloux, Robin Bériault, Joseph Lemire, Ranji Singh, Daniel R. Chénier, Robert D. Hamel, Vasu D. Appanna (2007). "The Tricarboxylic Acid Cycle, an Ancient Metabolic Network with a Novel Twist.". PLOS ONE 2 (8): e690. doi:10.1371/journal.pone.0000690. PMID 17668068. Bibcode: 2007PLoSO...2..690M.

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