Phase Genomics

Short description: American genomic sequencing company

Phase Genomics

Type| Startup company
Industry| Biotechnology
Founded| 2015
Founders| Ivan Liachko, Shawn Sullivan
Headquarters|

Seattle, Washington, US

Key people

| Ivan Liachko (CEO, president), Shawn Sullivan (CTO)
Website| {{{1}}}

Phase Genomics is an American biotechnology company based in Seattle, Washington. The company develops proximity ligation kits and Hi-C sequencing technology used to analyze chromosomes. Phase Genomics sells proximity ligation kits, scientific services, and computational analyses.

## Contents

* 1 History
* 2 Research
* 3 References
* 4 External links

## History

The company was founded by Ivan Liachko and Shawn Sullivan in 2015. It was originally housed in the CoMotion biotech incubator at University of Washington before relocating to a separate facility. It develops proximity ligation kits and Hi-C sequencing technology used to analyze chromosomes. The company sells proximity ligation kits, scientific services, and computational analyses.[1]

## Research

Phase Genomics developed a library preparation kit for the Hi-C sequencing method previously developed by researchers Job Dekker and Eric Lander. The kits are used to study the architecture of genomes.[2] In 2018, Phase Genomics received a $1.5 million SBIR grant from the National Institute of Allergy and Infectious Diseases (NIAID) to research antimicrobial resistance using Hi-C technology. In January 2020, it was awarded an additional $1.5 million from NIAID for phase 2 SBIR funding.[3] In 2019, Phase Genomics received $200,000 from the Bill & Melinda Gates Foundation to improve computational methods of extracting genomic data in microbiome samples.[3][4] Later in 2019, the company was awarded $325,000 from the U.S. Department of Energy to research algae biofuels using proximity litigation technology for metagenome assembly.[4] In 2020, Phase Genomics received 2 grants totaling $3.9 million from the National Human Genome Research Institute and the Eunice Kennedy Shriver National Institute of Child Health and Human Development. The 3-year grants fund research on chromosomal abnormalities causing cancer, infertility, and reproductive issues.[1]

In June 2021, the company released a platform for discovering new viruses in microbiome samples.[5][6]

## References

1. ↑ 1.0 1.1 Stiffler, Lisa (2020-09-30). "Phase Genomics lands $3.9M in grants to improve testing for chromosomal abnormalities" (in en-US). https://www.geekwire.com/2020/phase-genomics-lands-3-9m-grants-improve-testing-chromosomal-abnormalities/.
2. ↑ LeMieux, Julianna (2018-11-15). "Precision Medicine Looks beyond DNA Sequences" (in en). Genetic Engineering & Biotechnology News 38 (20): 1, 22, 24–25. doi:10.1089/gen.38.20.02. ISSN 1935-472X.
3. ↑ 3.0 3.1 "Phase Genomics Wins $1.5M for Proximity Ligation-Based AMR Tracking" (in en-us). January 7, 2020. https://www.genomeweb.com/sequencing/phase-genomics-wins-15m-proximity-ligation-based-amr-tracking.
4. ↑ 4.0 4.1 Kotrba, Ron (October 22, 2019). "Phase Genomics awarded DOE grant for algae biofuel research" (in en). http://www.biodieselmagazine.com/articles/2516818/phase-genomics-awarded-doe-grant-for-algae-biofuel-research.
5. ↑ Gounot, Jean-Sebastien; Chia, Minghao; Bertrand, Denis; Saw, Woei-Yuh; Ravikrishnan, Aarthi; Low, Adrian; Ding, Yichen; Ng, Amanda Hui Qi et al. (2022-10-13). "Genome-centric analysis of short and long read metagenomes reveals uncharacterized microbiome diversity in Southeast Asians" (in en). Nature Communications 13 (1): 6044. doi:10.1038/s41467-022-33782-z. ISSN 2041-1723. PMID 36229545. Bibcode: 2022NatCo..13.6044G.
6. ↑ "Phase Genomics Releases Platform for Discovering New Viruses in Microbiome Samples" (in en). 2021-06-15. https://www.businesswire.com/news/home/20210615005917/en/Phase-Genomics-Releases-Platform-for-Discovering-New-Viruses-in-Microbiome-Samples.

## External links

0.00

(0 votes)

Original source: https://en.wikipedia.org/wiki/Phase Genomics. Read more

|

Retrieved from "https://handwiki.org/wiki/index.php?title=Company:Phase_Genomics&oldid=540375"