Radiation Therapy Oncology Group

"The Radiation Therapy Oncology Group (RTOG) was initially organized in 1968 under the direction of Simon Kramer as a national cooperative group for the purpose of conducting radiation therapy research and clinical investigations in order to treat cancers, including endometrial and cervical cancer.[1] Funding from the National Cancer Institute (NCI) began in 1971.

Its first study was in 1968, an adjuvant methotrexate study for head and neck cancer. The methotrexate study employed combinations of radiation, methotrexate and surgery in the treatment of advanced head and neck cancer. 700 patients were used to this study clinical investigations in the area of head and neck cancer.[2] In 2009, it was reported RTOG accrued a total of about 60,000 patients for studies.[2] An academically controversial study RTOG published demonstrated good results for treating low-grade glioma, although as of 2015[update] this treatment was generally incompatible with chemotherapy options for treatment such as temozolomide.[3]

RTOG headquarters are located at the offices of the American College of Radiology in Philadelphia, Pennsylvania.[2]

## References

1. ↑ Small, William; Bosch, Walter R.; Harkenrider, Mathew M.; Strauss, Jonathan B.; Abu-Rustum, Nadeem; Albuquerque, Kevin V.; Beriwal, Sushil; Creutzberg, Carien L. et al. (2021-02-01). "NRG Oncology/RTOG Consensus Guidelines for Delineation of Clinical Target Volume for Intensity Modulated Pelvic Radiation Therapy in Postoperative Treatment of Endometrial and Cervical Cancer: An Update". International Journal of Radiation Oncology, Biology, Physics 109 (2): 413–424. doi:10.1016/j.ijrobp.2020.08.061. ISSN 1879-355X. PMID 32905846.
2. ↑ 2.0 2.1 2.2 RTOG - History
3. ↑ Laack, Nadia N.; Sarkaria, Jann N.; Buckner, Jan C. (July 2015). "Radiation Therapy Oncology Group 9802: Controversy or Consensus in the Treatment of Newly Diagnosed Low-Grade Glioma?". Seminars in Radiation Oncology 25 (3): 197–202. doi:10.1016/j.semradonc.2015.02.004. ISSN 1532-9461. PMID 26050590.

## External links

* Radiation Therapy Oncology Group

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