Transplant glomerulopathy

Micrograph showing a glomerulus with changes characteristic of a transplant glomerulopathy. PAS stain.
Specialty| Pathology

Transplant glomerulopathy (TG) is a disease of the glomeruli in transplanted kidneys. It is a type of renal injury often associated with chronic antibody-mediated rejection. However, transplant glomerulopathy is not specific for chronic antibody-mediated rejection; it may be the result of a number of disease processes affecting the glomerular endothelium.[1]

## Contents

* 1 Pathology
* 2 See also
* 3 References

## Pathology

It is characterized by glomerular basement membrane thickening (referred to as tram-tracking of the basement membrane), increased mesangial matrix and segmental and global glomerulosclerosis.[citation needed]

The differential diagnosis of tram-tracking includes membranoproliferative glomerulonephritis (especially hepatitis C), and thrombotic microangiopathies.[1]

* Intermed. mag.

* High mag.

## See also

* Kidney transplant
* Chronic rejection

## References

1. ↑ 1.0 1.1 Haas, M. (Oct 2011). "Transplant glomerulopathy: it's not always about chronic rejection.". Kidney Int 80 (8): 801–3. doi:10.1038/ki.2011.192. PMID 21960169.

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