Acrokeratoelastoidosis of Costa

Classification and external resources
OMIM | 101850
DiseasesDB | 29804
eMedicine | article/1113926

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief:  Kiran Singh, M.D. [2]

## Overview

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Acrokeratoelastoidosis of Costa (also known as "Keratoelastoidosis marginalis"[1]) is a familial condition characterized by multiple keratotic papules on the dorsum of the hands and feet, palms, soles, in which electron microscopy shows rarified, abnormal elastic tissue.[2]:993[3]:214

It was characterized in 1953.[4]

## Diagnosis

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### Physical Examination

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#### Skin

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##### Feet

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* Acrokeratoelastoidosis. Adapted from Dermatology Atlas.[5]

* Acrokeratoelastoidosis. Adapted from Dermatology Atlas.[5]

* Acrokeratoelastoidosis. Adapted from Dermatology Atlas.[5]

* Acrokeratoelastoidosis. Adapted from Dermatology Atlas.[5]

* Acrokeratoelastoidosis. Adapted from Dermatology Atlas.[5]

Treatments such as liquid nitrogen, salicylic acid, tretinoin, and prednisone have been tried, though with limited success.[6]

## See also

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* Skin lesion
* List of cutaneous conditions

## References

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1. ↑ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0.CS1 maint: Multiple names: authors list (link)
2. ↑ Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.
3. ↑ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
4. ↑ Costa OG (1953). "Akrokerato-elastoidosis; a hitherto undescribed skin disease". Dermatologica. 107 (3): 164–8. doi:10.1159/000256794. PMID 13116681.
5. ↑ 5.0 5.1 5.2 5.3 5.4 "Dermatology Atlas".
6. ↑ Zhai Z, Yang X, Hao F (2006). "Acrokeratoelastoidosis". Eur J Dermatol. 16 (2): 201–2. PMID 16613753.CS1 maint: Multiple names: authors list (link)