Amsterdam criteria

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The Amsterdam criteria identify families likely to have Hereditary nonpolyposis colorectal cancer (HNPCC).

At least 3 relatives with a HNPCC-associated cancer: colorectal cancer, or cancer of the endometrium, small intestine, ureter or renal pelvis.

* One patient should be a first degree relative of the other two

* At least two successive generations should be affected

* At least one tumour should be diagnosed <50 years of age

* Familial adenomatous polyposis should be excluded in the colorectal cancer case (if any)

* Tumours should be verified by histopathologic examination

## References

[edit | edit source]

* http://www.jeffersonhospital.org/cancer/article3099.html

* http://www.medscape.com/viewarticle/466572_4

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