Bariatric surgery

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In surgery, Bariatric surgery is defined as "surgical procedures aimed at affecting metabolism and producing major weight reduction in patients with morbid obesity."[1]

## Contents

* 1 Complications
* 1.1 Polyneuropathy
* 2 See also
* 3 External links
* 4 References

## Complications[edit | edit source]

Neurologic complications have been reviewed[2].

### Polyneuropathy[edit | edit source]

Thiamine deficiency after bariatric surgery has been reported to display demyelination by nerve conduction study[3] although per Shible, citing the two Koike reports, this may be late stage finding[4] and due to severe protein calorie malnutrition[5].

After bariatric surgery, 6% of patients developed polyneuropathy (none showed demyelination although inflammation was present) [6]. One form of neuropathy is beriberi from thiamine deficiency[7]. However, both axonal and demyelination have been reported[8]. See Beriberi other diagnostic studies.

However, demyelination after bariatric surgery may be associated with:

* Copper deficiency[9]. This patient also received treatment for immune globulin for possible Guillain-Barre Syndrome.
* Guillain-Barre Syndrome including a case with axonal loss and positive anti-GM1, anti-MAG, anti-GD1a antibodies[10] and a case and with demeyllination with anti-GM1 IgG and anti-GD1a antibodies[11].

## See also[edit | edit source]

## External links[edit | edit source]

## References[edit | edit source]

1. ↑ Anonymous (2025), Bariatric surgery (English). Medical Subject Headings. U.S. National Library of Medicine.
2. ↑ Landais A (2014). "Neurological complications of bariatric surgery". Obes Surg. 24 (10): 1800–7. doi:10.1007/s11695-014-1376-x. PMID 25060718.
3. ↑ Koike H, Misu K, Hattori N, Ito S, Ichimura M, Ito H; et al. (2001). "Postgastrectomy polyneuropathy with thiamine deficiency". J Neurol Neurosurg Psychiatry. 71 (3): 357–62. doi:10.1136/jnnp.71.3.357. PMC 1737557. PMID 11511711.CS1 maint: Multiple names: authors list (link)  "Unmyelinated fibre density was also decreased (998 to 16 956 fibres/mm2). In teased fibre studies, the frequency of fibres with axonal degeneration ranged from 1% to 96%, while segmental demyelination and remyelination were rare"
4. ↑ Shible AA, Ramadurai D, Gergen D, Reynolds PM (2019). "Dry Beriberi Due to Thiamine Deficiency Associated with Peripheral Neuropathy and Wernicke's Encephalopathy Mimicking Guillain-Barré syndrome: A Case Report and Review of the Literature". Am J Case Rep. 20: 330–334. doi:10.12659/AJCR.914051. PMC 6429982. PMID 30862772.CS1 maint: Multiple names: authors list (link)  "Neuronal biopsies from affected tissues from patients with dry beriberi have been reported to show predominantly axonal degeneration and progression to demyelination in end-stage disease"
5. ↑ Chopra JS, Dhand UK, Mehta S, Bakshi V, Rana S, Mehta J (1986). "Effect of proteincalorie malnutrition on peripheral nerves. A clinical, electrophysiological and histopathological study". Brain. 109 ( Pt 2): 307–23. doi:10.1093/brain/109.2.307. PMID 3082465.CS1 maint: Multiple names: authors list (link)
6. ↑ Thaisetthawatkul P, Collazo-Clavell ML, Sarr MG, Norell JE, Dyck PJ (2004). "A controlled study of peripheral neuropathy after bariatric surgery". Neurology. 63 (8): 1462–70. doi:10.1212/01.wnl.0000142038.43946.06. PMID 15505166.CS1 maint: Multiple names: authors list (link)
7. ↑ Stroh C, Meyer F, Manger T (2014). "Beriberi, a severe complication after metabolic surgery - review of the literature". Obes Facts. 7 (4): 246–52. doi:10.1159/000366012. PMC 5644786. PMID 25095897.CS1 maint: Multiple names: authors list (link)
8. ↑ Philippi N, Vinzio S, Collongues N, Vix M, Boehm N, Tranchant C; et al. (2011). "[Peripheral neuropathies after bariatric surgery]". Rev Neurol (Paris). 167 (8–9): 607–14. doi:10.1016/j.neurol.2011.01.011. PMID 21514611.CS1 maint: Multiple names: authors list (link)
9. ↑ Amin A, Khoury NC, Lacayo M, Kostanyan S (2022). "Copper Deficiency-Induced Neuropathy After Bariatric Surgery Disguised as Demyelinating Disease: A Case Report". Cureus. 14 (2): e22705. doi:10.7759/cureus.22705. PMC 8967068 Check `|pmc=` value (help). PMID 35386142 Check `|pmid=` value (help).CS1 maint: Multiple names: authors list (link)
10. ↑ Landais AF (2014). "Rare neurologic complication of bariatric surgery: acute motor axonal neuropathy (AMAN), a severe motor axonal form of the Guillain Barré syndrome". Surg Obes Relat Dis. 10 (6): e85–7. doi:10.1016/j.soard.2014.02.019. PMID 24913591.
11. ↑ Ishaque N, Khealani BA, Shariff AH, Wasay M (2015). "Guillain-Barré syndrome (demyelinating) six weeks after bariatric surgery: A case report and literature review". Obes Res Clin Pract. 9 (4): 416–9. doi:10.1016/j.orcp.2015.02.001. PMID 25765350.CS1 maint: Multiple names: authors list (link) . The report stated "fully compliant with the recommended diet plan and vitamin supplements" although these levels were not reported for confirmation.