Bladder cancer treatment

Bladder cancer Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Bladder cancer from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Staging

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X Ray

MRI

Electrocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Biopsy

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Bladder cancer treatment On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Bladder cancer treatment

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Bladder cancer treatment

CDC on Bladder cancer treatment

Bladder cancer treatment in the news

Blogs on Bladder cancer treatment

Directions to Hospitals Treating Bladder cancer

Risk calculators and risk factors for Bladder cancer treatment

Steven C. Campbell, M.D., Ph.D.

## Treatment

[edit | edit source]

The treatment of bladder cancer depends on how deep the tumor invades into the bladder wall. Superficial tumors (those not entering the muscle layer) can be "shaved off" using an electrocautery device attached to a cystoscope. Immunotherapy in the form ofBCG instillation is also used to treat and prevent the recurrence of superficial tumors.[1] BCG immunotherapy is effective in up to 2/3 of the cases at this stage. Instillations of chemotherapy into the bladder can also be used to treat superficial disease.

Untreated, superficial tumors may gradually begin to infiltrate the muscular wall of the bladder. Tumors that infiltrate the bladder require more radical surgery where part or all of the bladder is removed (a cystectomy) and the urinary stream is diverted. In some cases, skilled surgeons can create a substitute bladder (a neobladder) from a segment of intestinal tissue, but this largely depends upon patient preference, age of patient, renal function, and the site of the disease.

A combination of radiation and chemotherapy can also be used to treat invasive disease. It has not yet been determined how the effectiveness of this form of treatment compares to that of radical ablative surgery.

There is weak observational evidence from one very small study (84) to suggest that the concurrent use of statins is associated with failure of BCG immunotherapy.[2]

## References

[edit | edit source]

1. ↑ "BCG immunotherapy of bladder cancer: 20 years on". 353 (9165). 1999: 1689&ndash, 94.
2. ↑ "Use of statins and outcome of BCG treatment for bladder cancer". 355 (25). 2006: 2705&ndash, 7.

Template:Tumors

bs:Rak mokraćnog mjehura da:Blærecancer de:Blasenkrebs hr:Rak mokraćnog mjehura no:Urinveiskreft fi:Virtsarakon syöpä sv:Urinvägscancer

Template:WH Template:WS