Bovine spongiform encephalopathy causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief:  Adnan Ezici, M.D[2]

## Overview

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Bovine spongiform encephalopathy (BSE) may be caused by different strains including the classic BSE strain (which is responsible for the outbreak in the United Kingdom) and two atypical strains (H and L strains).

## Causes

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Bovine spongiform encephalopathy (BSE) may be caused by different strains including the classic BSE strain (which is responsible for the outbreak in the United Kingdom) and two atypical strains (H and L strains).[1]

* Classic BSE strain has been causally linked to variant Creutzfeldt-Jakob disease (vCJD) in humans.

* Atypical BSE strains (H-type and L-type BSE) usually occur spontaneously (although might be transmitted through feed or the environment).

## References

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1. ↑ Casalone C, Hope J (2018). "Atypical and classic bovine spongiform encephalopathy". Handb Clin Neurol. 153: 121–134. doi:10.1016/B978-0-444-63945-5.00007-6. PMID 29887132.

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