Brugada syndrome electrophysiologic studies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:  Sogand Goudarzi, MD [2]

## Overview

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Electrophysiologic study may be helpful in the diagnosis of Brugada syndrome. Some groups have advocated that programmed electrical stimulation (PES) be performed to induce ventricular fibrillation for risk assessment in Brugada patients other groups have not reproduced the predictive value of these tests, so the value of programmed electrical stimulation (PES) and inducibility remains controversial.

## Other Diagnostic Studies

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* Electrophysiologic study may be helpful in the diagnosis of Brugada syndrome.[1]
* Patients who are inducible at the time electrophysiologic study have an eightfold increased risk of aborted sudden cardiac death compared with those patients who are not inducible.[2]
* Some groups have advocated that programmed electrical stimulation (PES) be performed to induce ventricular fibrillation for risk assessment in Brugada patientso ther groups have not reproduced the predictive value of these tests, so the value of programmed electrical stimulation (PES) and inducibility remains controversia.[3][4][5][6][7]

## References

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1. ↑ Letsas KP, Georgopoulos S, Vlachos K, Karamichalakis N, Liatakis I, Korantzopoulos P, Liu T, Efremidis M, Sideris A (2016). "Brugada Syndrome:Risk Stratification And Management". J Atr Fibrillation. 9 (2): 1413. doi:10.4022/jafib.1413. PMC 5129684. PMID 27909531.
2. ↑ Suryanarayana, Prakash; Garza, Hyon-he K.; Klewer, Jacob; Hutchinson, Mathew D. (2018). "Electrophysiologic Considerations After Sudden Cardiac Arrest". Current Cardiology Reviews. 14 (2): 102–108. doi:10.2174/1573403X14666180507164443. ISSN 1573-403X.
3. ↑ Brugada J, Brugada R, Antzelevitch C, Towbin J, Nademanee K, Brugada P (2002). "Long-term follow-up of individuals with the electrocardiographic pattern of right bundle-branch block and ST-segment elevation in precordial leads V1 to V3". Circulation. 105 (1): 73–8. PMID 11772879. Retrieved 2012-10-13. Unknown parameter `|month=` ignored (help)CS1 maint: Multiple names: authors list (link)
4. ↑ Brugada P, Brugada R, Mont L, Rivero M, Geelen P, Brugada J (2003). "Natural history of Brugada syndrome: the prognostic value of programmed electrical stimulation of the heart". Journal of Cardiovascular Electrophysiology. 14 (5): 455–7. PMID 12776858. Retrieved 2012-10-13. Unknown parameter `|month=` ignored (help)CS1 maint: Multiple names: authors list (link)
5. ↑ Priori SG, Napolitano C, Gasparini M, Pappone C, Della Bella P, Giordano U, Bloise R, Giustetto C, De Nardis R, Grillo M, Ronchetti E, Faggiano G, Nastoli J (2002). "Natural history of Brugada syndrome: insights for risk stratification and management". Circulation. 105 (11): 1342–7. PMID 11901046. Retrieved 2012-10-13. Unknown parameter `|month=` ignored (help)CS1 maint: Multiple names: authors list (link)
6. ↑ Eckardt L, Probst V, Smits JP, Bahr ES, Wolpert C, Schimpf R, Wichter T, Boisseau P, Heinecke A, Breithardt G, Borggrefe M, LeMarec H, Böcker D, Wilde AA (2005). "Long-term prognosis of individuals with right precordial ST-segment-elevation Brugada syndrome". Circulation. 111 (3): 257–63. doi:10.1161/01.CIR.0000153267.21278.8D. PMID 15642768. Retrieved 2012-10-13. Unknown parameter `|month=` ignored (help)CS1 maint: Multiple names: authors list (link)
7. ↑ Makimoto, Hisaki; Kamakura, Shiro; Aihara, Naohiko; Noda, Takashi; Nakajima, Ikutaro; Yokoyama, Teruki; Doi, Atsushi; Kawata, Hiro; Yamada, Yuko; Okamura, Hideo; Satomi, Kazuhiro; Aiba, Takeshi; Shimizu, Wataru (2012). "Clinical impact of the number of extrastimuli in programmed electrical stimulation in patients with Brugada type 1 electrocardiogram". Heart Rhythm. 9 (2): 242–248. doi:10.1016/j.hrthm.2011.09.053. ISSN 1547-5271.

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