CERK

Ceramide kinase

Identifiers
Symbols|  CERK ; DKFZp434E0211; FLJ21430; FLJ23239; KIAA1646; LK4; MGC131878; dA59H18.2; dA59H18.3; hCERK
External IDs|  Template:OMIM5 Template:MGI HomoloGene: 11247
| Gene ontology

Molecular function | Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
Cellular component | Template:GNF GO
Biological process | Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species|  Human|  Mouse
Entrez|  n/a|  n/a
Ensembl|  n/a|  n/a
UniProt|  n/a|  n/a
RefSeq (mRNA)|  n/a|  n/a
RefSeq (protein)|  n/a|  n/a
Location (UCSC)|  n/a|  n/a
PubMed search|  n/a|  n/a

Ceramide kinase, also known as CERK, is a human gene.[1]

## References

[edit | edit source]

1. ↑ "Entrez Gene: CERK ceramide kinase".

## Further reading

[edit | edit source]

* Hinkovska-Galcheva VT, Boxer LA, Mansfield PJ; et al. (1999). "The formation of ceramide-1-phosphate during neutrophil phagocytosis and its role in liposome fusion". J. Biol. Chem. 273 (50): 33203–9. PMID 9837889.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
* Dunham I, Shimizu N, Roe BA; et al. (1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
* Pitson SM, D'andrea RJ, Vandeleur L; et al. (2001). "Human sphingosine kinase: purification, molecular cloning and characterization of the native and recombinant enzymes". Biochem. J. 350 Pt 2: 429–41. PMID 10947957.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
* Hirosawa M, Nagase T, Murahashi Y; et al. (2001). "Identification of novel transcribed sequences on human chromosome 22 by expressed sequence tag mapping". DNA Res. 8 (1): 1–9. PMID 11258795.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
* Sugiura M, Kono K, Liu H; et al. (2002). "Ceramide kinase, a novel lipid kinase. Molecular cloning and functional characterization". J. Biol. Chem. 277 (26): 23294–300. doi:10.1074/jbc.M201535200. PMID 11956206.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
* Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
* Pettus BJ, Bielawska A, Spiegel S; et al. (2003). "Ceramide kinase mediates cytokine- and calcium ionophore-induced arachidonic acid release". J. Biol. Chem. 278 (40): 38206–13. doi:10.1074/jbc.M304816200. PMID 12855693.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
* Mitsutake S, Kim TJ, Inagaki Y; et al. (2004). "Ceramide kinase is a mediator of calcium-dependent degranulation in mast cells". J. Biol. Chem. 279 (17): 17570–7. doi:10.1074/jbc.M312885200. PMID 14769792.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
* Collins JE, Wright CL, Edwards CA; et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMID 15461802.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
* Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
* Hinkovska-Galcheva V, Boxer LA, Kindzelskii A; et al. (2005). "Ceramide 1-phosphate, a mediator of phagocytosis". J. Biol. Chem. 280 (28): 26612–21. doi:10.1074/jbc.M501359200. PMID 15899891.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
* Kim TJ, Mitsutake S, Kato M, Igarashi Y (2005). "The leucine 10 residue in the pleckstrin homology domain of ceramide kinase is crucial for its catalytic activity". FEBS Lett. 579 (20): 4383–8. doi:10.1016/j.febslet.2005.06.079. PMID 16081073.CS1 maint: Multiple names: authors list (link)
* Wijesinghe DS, Massiello A, Subramanian P; et al. (2006). "Substrate specificity of human ceramide kinase". J. Lipid Res. 46 (12): 2706–16. doi:10.1194/jlr.M500313-JLR200. PMID 16170208.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
* Van Overloop H, Gijsbers S, Van Veldhoven PP (2006). "Further characterization of mammalian ceramide kinase: substrate delivery and (stereo)specificity, tissue distribution, and subcellular localization studies". J. Lipid Res. 47 (2): 268–83. doi:10.1194/jlr.M500321-JLR200. PMID 16269826.CS1 maint: Multiple names: authors list (link)
* Kim TJ, Mitsutake S, Igarashi Y (2006). "The interaction between the pleckstrin homology domain of ceramide kinase and phosphatidylinositol 4,5-bisphosphate regulates the plasma membrane targeting and ceramide 1-phosphate levels". Biochem. Biophys. Res. Commun. 342 (2): 611–7. doi:10.1016/j.bbrc.2006.01.170. PMID 16488390.CS1 maint: Multiple names: authors list (link)
* Mitra P, Maceyka M, Payne SG; et al. (2007). "Ceramide kinase regulates growth and survival of A549 human lung adenocarcinoma cells". FEBS Lett. 581 (4): 735–40. doi:10.1016/j.febslet.2007.01.041. PMID 17274985.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
* Lamour NF, Stahelin RV, Wijesinghe DS; et al. (2007). "Ceramide kinase uses ceramide provided by ceramide transport protein: localization to organelles of eicosanoid synthesis". J. Lipid Res. 48 (6): 1293–304. doi:10.1194/jlr.M700083-JLR200. PMID 17392267.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

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