Carcinoma of the penis primary prevention

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Editor(s)-in-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-632-7753; Joel Gelman, M.D. [2], Director of the Center for Reconstructive Urology and Associate Clinical Professor in the Department of Urology at the University of California,Irvine

## Overview

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Effective measures for the primary prevention of carcinoma of the penis include circumcision, good personal hygiene, and safer sexual practices. Gardasil vaccine is recommended for men to prevent HPV infection.

## Primary Prevention

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Effective measures for the primary prevention of penile cancer include:[1]

* Circumcision
* Good personal hygiene
* Safer sexual practices such as:

* Abstinence
* Limiting the number of sexual partners
* Use of condoms to prevent HPV infection

* Vaccine

* A quadri-valent vaccine to prevent HPV infection, Gardasil, has been developed, successfully tested and approved for women by the US Food and Drug Administration.[2]Approval for men is expected in 2008. It is licensed and in production, and could substantially reduce the incidence of HPV infection in men, the incidence of genital warts and ano-genital cancers including penile cancer, and mortality.[3]

## References

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1. ↑ Cancer - penis. MedlinePlus 2015. https://www.nlm.nih.gov/medlineplus/ency/article/001276.htm
2. ↑ Crum C, Jones C, Kirkpatrick P (2006). "Quadrivalent human papillomavirus recombinant vaccine". Nat Rev Drug Discov. 5 (8): 629–30. doi:10.1038/nrd2117. PMID 16918020.CS1 maint: Multiple names: authors list (link)
3. ↑ Lehtinen M, Paavonen J (2004). "Vaccination against human papillomaviruses shows great promise". Lancet. 364 (9447): 1731–2. doi:10.1016/S0140-6736(04)17410-2. PMID 15541429.

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