Cholangiocarcinoma risk factors

Cholangiocarcinoma Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Cholangiocarcinoma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Cholangiocarcinoma risk factors On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Cholangiocarcinoma risk factors

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Cholangiocarcinoma risk factors

CDC on Cholangiocarcinoma risk factors

Cholangiocarcinoma risk factors in the news

Blogs on Cholangiocarcinoma risk factors

Directions to Hospitals Treating Cholangiocarcinoma

Risk calculators and risk factors for Cholangiocarcinoma risk factors

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:  Farima Kahe M.D. [2], Suveenkrishna Pothuru, M.B,B.S. [3]

## Overview

[edit | edit source]

Common risk factors in the development of cholangiocarcinoma include primary sclerosing cholangitis, fibropolycystic liver disease such as choledochal cysts, hepatolithiasis and recurrent pyogenic cholangitis.

## Risk Factors

[edit | edit source]

* Common risk factors in the development of cholangiocarcinoma include primary sclerosing cholangitis, fibropolycystic liver disease such as choledochal cysts, hepatolithiasis and recurrent pyogenic cholangitis.

### Common Risk Factors

[edit | edit source]

* Common risk factors in the development of cholangiocarcinoma include:[1][2][3][4][5]
* Primary sclerosing cholangitis
* Cirrhosis
* Viral infections
* HIV
* EBV
* Hepatitis viruses
* Hepatitis B
* Hepatitis C
* Liver fluke infections
* Hepatolithiasis
* Choledochal cysts
* Infusion of certain chemical agents such as naphthenic acids
* Recurrent pyogenic cholangitis
* Opisthorchis viverrini
* Clonorchis sinensis
* Caroli's disease
* Inherited disorders
* Lynch syndrome
* Biliary papillomatosis

### Less Common Risk Factors

[edit | edit source]

* Less common risk factors in the development of cholangiocarcinoma include:[6]
* Thorotrast
* Diabetes
* Obesity
* Alcohol consumption
* Smoking

## References

[edit | edit source]

1. ↑ Al-Bahrani R, Abuetabh Y, Zeitouni N, Sergi C (2013). "Cholangiocarcinoma: risk factors, environmental influences and oncogenesis". Ann. Clin. Lab. Sci. 43 (2): 195–210. PMID 23694797.
2. ↑ Tyson GL, El-Serag HB (2011). "Risk factors for cholangiocarcinoma". Hepatology. 54 (1): 173–84. doi:10.1002/hep.24351. PMC 3125451. PMID 21488076.
3. ↑ Ben-Menachem T (2007). "Risk factors for cholangiocarcinoma". Eur J Gastroenterol Hepatol. 19 (8): 615–7. doi:10.1097/MEG.0b013e328224b935. PMID 17625428.
4. ↑ Gatto M, Alvaro D (2010). "Cholangiocarcinoma: risk factors and clinical presentation". Eur Rev Med Pharmacol Sci. 14 (4): 363–7. PMID 20496549.
5. ↑ Acalovschi M (2004). "Cholangiocarcinoma: risk factors, diagnosis and management". Rom J Intern Med. 42 (1): 41–58. PMID 15529594.
6. ↑ Razumilava N, Gores GJ (2013). "Classification, diagnosis, and management of cholangiocarcinoma". Clin. Gastroenterol. Hepatol. 11 (1): 13–21.e1, quiz e3–4. doi:10.1016/j.cgh.2012.09.009. PMC 3596004. PMID 22982100.

Template:WH Template:WS